Relative bioavailability of calcium from calcium formate, calcium citrate, and calcium carbonate

Journal of Pharmacology and Experimental Therapeutics

Volumn 313, Issue 3, 2005, Pages 1217-1222

  Hanzlik, Robert P ^a,c   Fowler, Stephen C ^a   Fisher, Daniel H ^b  

^a UNIVERSITY OF KANSAS   (United States)

^b AAI Development Services   (United States)

^c KU MDCM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; CALCIUM CARBONATE; CALCIUM FORMATE; CITRATE CALCIUM; FORMIC ACID DERIVATIVE; PARATHYROID HORMONE; UNCLASSIFIED DRUG;

ADULT; AREA UNDER THE CURVE; ARTICLE; CALCIUM BLOOD LEVEL; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DIET SUPPLEMENTATION; DRUG BIOAVAILABILITY; DRUG EFFECT; FEMALE; HUMAN; NORMAL HUMAN; PRIORITY JOURNAL;

ABSORPTION; ADULT; AREA UNDER CURVE; BIOLOGICAL AVAILABILITY; CALCIUM; CALCIUM CARBONATE; CALCIUM CITRATE; CROSS-OVER STUDIES; FEMALE; FORMATES; HUMANS; PARATHYROID HORMONE;

EID: 19444378922     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: 10.1124/jpet.104.081893     Document Type: Article

References (32)

1. Abrams SA (2003) Issues concerning calcium absorption and bone health, in Nutritional Aspects of Bone Health (New SA and Bonjour J-P eds) pp 157-173, The Royal Society of Chemistry, Cambridge.
2. Blanchard J and Aeschlimann J-M (1989) Calcium absorption in man: some dosing recommendations. J Pharmacokinet Biopharm 17:631-644.
3. Charles P (1992) Calcium absorption and calcium bioavailability. J Intern Med 231:161-168.
4. DeGrazia JA, Ivanovich P, Fellows H, and Rich C (1965) A double isotope method for measurement of intestinal absorption of calcium in man. J Lab Clin Med 66:822-829.
5. DeLuca HF (2003) inventor, Wisconsin Alumni Research Foundation, assignee. Calcium formate for use as a dietary supplement. U.S. patent 6,528,542. 2003 Mar 4.
6. el-Hajj Fuleihan G, Klerman EB, Brown EN, Choe Y, Brown EM, and Czeisler CA (1997) The parathyroid hormone circadian rhythm is truly endogenous-a general clinical research center study. J Clin Endocrinol Metab 82:281-286.
7. Guéguen L and Pointillart A (2000) The bioavailability of dietary calcium. J Am Coll Nutr 19:119S-136S.
8. Hanzlik RP, Fowler RP, and Eells JT (2005) Absorption and elimination of formate following oral administration of calcium formate in female human subjects. Drug Metab Dispos 33:282-286.
9. Heaney RP (2001) Factors influencing the measurement of bioavailability, taking calcium as a model. J Nutr 131:S1334-S1348.
10. Heaney RP (2003a) Quantifying human calcium absorption using pharmacokinetic methods. J Nutr 133:1224-1226.
11. Heaney RP (2003b) Sensitivity of parathyroid hormone response to calcium intake. Am J Clin Nutr 78:493-497.
12. Heaney RP, Berner B, and Louie-Helm J (2000) Dosing regimen for calcium supplementation. J Bone Miner Res 15:2291.
13. Heaney RP, Dowell MS, Bierman J, Hale CA, and Bendich A (2001) Absorbability and cost effectiveness in calcium supplementation. J Am Coll Nutr 20:239-246.
14. Heaney RP and Recker RR (1985) Estimation of true calcium absorption. Ann Intern Med 103:516-521.
15. Heaney RP, Smith KT, Recker RR, and Hinders SM (1989) Meal effects on calcium absorption. Am J Clin Nutr 49:372-376.
16. Heaney RP, Weaver CM, and Fitzsimmons ML (1990) Influence of calcium load on absorption fraction. J Bone Miner Res 5:1135-1138.
17. Heller HJ, Greer LG, Haynes SD, Pondexter JR, and Pak CY (2000) Pharmacokinetic and pharmacodynamic comparison of two calcium supplements in postmenopausal women. J Clin Pharmacol 40:1237-1244.
18. Heller HJ, Stewart A, Haynes S, and Pak CY (1999) Pharmacokinetics of calcium absorption from two commercial calcium supplements. J Clin Pharmacol 39:1151-1154.
19. Ireland P and Fordtran JS (1973) Effect of dietary calcium and age on jejunal calcium absorption in humans studied by intestinal perfusion. J Clin Investig 52:2672-2681.
20. Levenson DI and Bockman RS (1994) A review of calcium preparations. Nutr Rev 52:221-232.
21. Martini L and Wood RJ (2002) Relative bioavailability of calcium-rich dietary sources in the elderly. Am J Clin Nutr 76:1345-1350.
22. McKane WR, Khosla S, Egan KS, and Robins SP (1996) Role of calcium intake in modulating age-related increases in parathyroid function and bone resorption. J Clin Endocrinol Metab 81:1699-1703.
23. Nielsen HK, Laurberg P, Brixen K, and Mosekilde L (1991) Relations between diurnal variations in serum osteocalcin, cortison, parathyroid hormone and ionized calcium in normal individuals. Acta Endocrinol 124:391-398.
24. Porter C (2003) Vitamin and mineral supplements: part 1. The Rx Consultant 12:1-8.
25. Reginster JY, Denis D, Bartsch R, Deroisy R, Zegels B, and Franchimont P (1993) Acute biochemical variations induced by four different calcium salts in healthy male volunteers. Osteoporos Int 3:271-275.
26. Report (2001) NIH consensus development panel on osteoporosis prevention, diagnosis and therapy. J Am Med Assoc 285:785-795.
27. Roth P and Werner E (1985) Interrelations of radiocalcium absorption tests and their clinical relevance. Miner Electrolyte Metab 11:351-357.
28. Sakhaee K, Bhuket T, Adams-Huet B, and Sudhaker Rao D (1999) Meta-analysis of calcium bioavailability: a comparison of calcium citrate with calcium carbonate. Am J Ther 6:313-321.
29. Smith DL, Atkin C, and Westfender C (1985) Stable isotopes of calcium as tracers: methodology. Clin Chim Acta 146:97-101.
30. Vesely DL, Sothern RB, Scheving LE, Bremner FW, Third JL, McConnick JB, Dawson S, Kahn S, Augustine G, Ryan M, et al. (1996) Circadian relationships between circulating atrial natriuretic peptides and serum calcium and phosphate in healthy humans. Metabolism 45:1021-1028.
31. Weaver CM, Heaney RP, Martin BR, and Fitzsimmons ML (1991) Human calcium absorption from whole wheat products. J Nutr 121:1769-1775.
32. Wood RJ and Martini L (2003) Reply to R. P. Heaney. Am J Clin Nutr 78:493-494.