The growth and tumor suppressor NORE1A is a cytoskeletal protein that suppresses growth by inhibition of the ERK pathway

Journal of Biological Chemistry

Volumn 281, Issue 12, 2006, Pages 8143-8152

  Moshnikova, Anna ^a   Frye, Judson ^a   Shay, Jerry W ^b   Minna, John D ^c   Khokhlatchev, Andrei V ^a  

^a UNIVERSITY OF VIRGINIA HEALTH SYSTEM   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^c UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; BIOASSAY; CYTOLOGY; GROWTH KINETICS; MOLECULAR BIOLOGY; ONCOLOGY; TUMORS;

CENTROSOMES; CYTOSKELETAL PROTEIN; MICROTUBULES; ONCOGENES; TUMOR SUPPRESSOR NORE1A;

PROTEINS;

CYTOSKELETON PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; CYCLIN DEPENDENT KINASE INHIBITOR 1A; GREEN FLUORESCENT PROTEIN; MONOMERIC GUANINE NUCLEOTIDE BINDING PROTEIN; RAS PROTEIN; RASSF5 PROTEIN, HUMAN; TUBULIN;

ARTICLE; CELL CYCLE; CELL CYCLE ARREST; CENTROSOME; CONTROLLED STUDY; CYTOSKELETON; GENE MUTATION; GROWTH INHIBITION; HUMAN; HUMAN CELL; LUNG ADENOCARCINOMA; LUNG ALVEOLUS CELL; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR GENE; BRONCHUS; CELL LINE; CELL PROLIFERATION; CHEMISTRY; DOWN REGULATION; EPITHELIUM CELL; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; GENE EXPRESSION REGULATION; GENETIC TRANSFECTION; GENETICS; IMMUNOPRECIPITATION; METABOLISM; MICROTUBULE; MUTATION; PHYSIOLOGY; PLASMID; PROTEIN BINDING; PROTEIN TERTIARY STRUCTURE; RETROVIRUS; TUMOR CELL LINE; WESTERN BLOTTING;

BLOTTING, WESTERN; BRONCHI; CELL CYCLE; CELL LINE; CELL LINE, TRANSFORMED; CELL LINE, TUMOR; CELL PROLIFERATION; CENTROSOME; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYTOSKELETON; DOWN-REGULATION; EPITHELIAL CELLS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FLOW CYTOMETRY; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, TUMOR SUPPRESSOR; GREEN FLUORESCENT PROTEINS; HUMANS; IMMUNOPRECIPITATION; MAP KINASE SIGNALING SYSTEM; MICROSCOPY, FLUORESCENCE; MICROTUBULES; MITOGEN-ACTIVATED PROTEIN KINASES; MONOMERIC GTP-BINDING PROTEINS; MUTATION; PLASMIDS; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RAS PROTEINS; RETROVIRIDAE; SIGNAL TRANSDUCTION; TRANSFECTION; TUBULIN;

EID: 33646349470     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M511837200     Document Type: Article

References (40)

1. Bos, J. L. (1989) Cancer Res. 49, 4682-4689
2. Egan, S. E., and Weinberg, R. A. (1993) Nature 365, 781-783
3. Shields, J. M., Pruitt, K., McFall, A., Shaub, A., and Der, C. J. (2000) Trends Cell Biol. 10, 147-154
4. Marshall, C. J. (1996) Curr. Opin. Cell Biol. 8, 197-204
5. Vavvas, D., Li, X., Avruch, J., and Zhang, X. F. (1998) J. Biol. Chem. 273, 5439-5442
6. Tommasi, S., Dammann, R., Jin, S. G., Zhang, X. F., Avruch, J., and Pfeifer, G. P. (2002) Oncogene 21, 2713-2720
7. Dammann, R., Li, C., Yoon, J. H., Chin, P. L., Bates, S., and Pfeifer, G. P. (2000) Nat. Genet. 25, 315-319
8. Comincini, S., Castiglioni, B. M., Foti, G. M., Del Vecchio, I., and Ferretti, L. (2001) Mamm. Genome 12, 150-156
9. Hull, J., Rowlands, K., Lockhart, E., Sharland, M., Moore, C., Hanchard, N., and Kwiatkowski, D. P. (2004) Hum. Genet. 114, 272-279
10. Dammann, R., Schagdarsurengin, U., Strunnikova, M., Rastetter, M., Seidel, C., Liu, L., Tommasi, S., and Pfeifer, G. P. (2003) Histol. Histopathol. 18, 665-677
11. Burbee, D. G., Forgacs, E., Zochbauer-Muller, S., Shivakumar, L., Fong, K., Gao, B., Randle, D., Kondo, M., Virmani, A., Bader, S., Sekido, Y., Latif, F., Milchgrub, S., Toyooka, S., Gazdar, A. F., Lerman, M. I., Zabarovsky, E., White, M., and Minna, J. D. (2001) J. Natl. Cancer Inst. 93, 691-699
12. Agathanggelou, A., Cooper, W. N., and Latif, F. (2005) Cancer Res. 65, 3497-3508
13. Hesson, L., Bieche, I., Krex, D., Criniere, E., Hoang-Xuan, K., Maher, E. R., and Latif, F. (2004) Oncogene 23, 2408-2419
14. Chow, L. S., Lo, K. W., Kwong, J., Wong, A. Y., and Huang, D. P. (2004) Oncol. Rep. 12, 781-787
15. Eckfeld, K., Hesson, L., Vos, M. D., Bieche, I., Latif, F., and Clark, G. J. (2004) Cancer Res. 64, 8688-8693
16. Vos, M. D., Ellis, C. A., Elam, C., Ulku, A. S., Taylor, B. J., and Clark, G. J. (2003) J. Biol. Chem. 278, 28045-28051
17. Levy, P., Vidaud, D., Leroy, K., Laurendeau, I., Wechsler, J., Bolasco, G., Parfait, B., Wolkenstein, P., Vidaud, M., and Bieche, I. (2004) Mol. Cancer 3, 20
18. Hesson, L. B., Wilson, R., Morton, D., Adams, C., Walker, M., Maher, E. R., and Latif, F. (2005) Oncogene 24, 3987-3994
19. Hesson, L., Dallol, A., Minna, J. D., Maher, E. R., and Latif, F. (2003) Oncogene 22, 947-954
20. Irimia, M., Fraga, M. F., Sanchez-Cespedes, M., and Esteller, M. (2004) Oncogene 23, 8695-8699
21. Vos, M. D., Martinez, A., Ellis, C. A., Vallecorsa, T., and Clark, G. J. (2003) J. Biol. Chem. 278, 21938-21943
22. Chen, J., Lui, W. O., Vos, M. D., Clark, G. J., Takahashi, M., Schoumans, J., Khoo, S. K., Petillo, D., Lavery, T., Sugimura, J., Astuti, D., Zhang, C., Kagawa, S., Maher, E. R., Larsson, C., Alberts, A. S., Kanayama, H. O., and Teh, B. T. (2003) Cancer Cell 4, 405-413
23. Aoyama, Y., Avruch, J., and Zhang, X. F. (2004) Oncogene 23, 3426-3433
24. Ortiz-Vega, S., Khokhlatchev, A., Nedwidek, M., Zhang, X. F., Dammann, R., Pfeifer, G. P., and Avruch, J. (2002) Oncogene 21, 1381-1390
25. Khokhlatchev, A., Rabizadeh, S., Xavier, R., Nedwidek, M., Chen, T., Zhang, X. F., Seed, B., and Avruch, J. (2002) Curr. Biol. 12, 253-265
26. Sambrook, J., and Russell, D. W. (2001) Molecular Cloning:ALaboratory Manual, 3rd Ed., Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
27. Randow, F., and Seed, B. (2001) Nat. Cell Biol. 3, 891-896
28. Ramirez, R. D., Sheridan, S., Girard, L., Sato, M., Kim, Y., Pollack, J., Peyton, M., Zou, Y., Kurie, J. M., Dimaio, J. M., Milchgrub, S., Smith, A. L., Souza, R. F., Gilbey, L., Zhang, X., Gandia, K., Vaughan, M. B., Wright, W. E., Gazdar, A. F., Shay, J. W., and Minna, J. D. (2004) Cancer Res. 64, 9027-9034
29. Hsu, L. C., and White, R. L. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 12983-12988
30. Cifone, M. A. (1982) Cancer Metastasis Rev. 1, 335-347
31. Dallol, A., Agathanggelou, A., Fenton, S. L., Ahmed-Choudhury, J., Hesson, L., Vos, M. D., Clark, G. J., Downward, J., Maher, E. R., and Latif, F. (2004) Cancer Res. 64, 4112-4116
32. Rong, R., Jin, W., Zhang, J., Sheikh, M. S., and Huang, Y. (2004) Oncogene 23, 8216-8230
33. Raman, M., and Cobb, M. H. (2003) Curr. Biol. 13, R886-R888
34. Chen, Z., Gibson, T. B., Robinson, F., Silvestro, L., Pearson, G., Xu, B., Wright, A., Vanderbilt, C., and Cobb, M. H. (2001) Chem. Rev. 101, 2449-2476
35. Song, M. S., Song, S. J., Ayad, N. G., Chang, J. S., Lee, J. H., Hong, H. K., Lee, H., Choi, N., Kim, J., Kim, H., Kim, J. W., Choi, E. J., Kirschner, M. W., and Lim, D. S. (2004) Nat. Cell Biol. 6, 129-137
36. Valenzuela, D. M., and Groffen, J. (1986) Nucleic Acids Res. 14, 843-852
37. Pergolizzi, R. G., Kreis, W., Rottach, C., Susin, M., and Broome, J. D. (1993) Cancer Invest. 11, 25-32
38. Thissen, J. A., Gross, J. M., Subramanian, K., Meyer, T., and Casey, P. J. (1997) J. Biol. Chem. 272, 30362-30370
39. Liu, L., Tommasi, S., Lee, D. H., Dammann, R., and Pfeifer, G. P. (2003) Oncogene 22, 8125-8136
40. Vos, M. D., Martinez, A., Elam, C., Dallol, A., Taylor, B. J., Latif, F., and Clark, G. J. (2004) Cancer Res. 64, 4244-4250