Inhibition of experimental gingivitis in beagle dogs with topical mercaptoalkylguanidines

Journal of Periodontology

Volumn 77, Issue 3, 2006, Pages 385-391

  Paquette, David W ^a   Rosenberg, Adam ^a   Lohinai, Zsolt ^b   Southan, Gary J ^c   Williams, Ray C ^a   Offenbacher, Steven ^a   Szabò, Csaba ^b,c  

^a UNIVERSITY OF NORTH CAROLINA   (United States)

^b SEMMELWEIS UNIVERSITY OF MEDICINE   (Hungary)

^c INOTEK CORPORATION   (United States)

Author keywords

Dogs; Gingivitis; Inducible nitric oxide synthase; Periodontal disease; Reactive nitrogen species

Indexed keywords

1 (2 MERCAPTOETHYL)GUANIDINE; GUANIDINOETHYLDISULFIDE; INDUCIBLE NITRIC OXIDE SYNTHASE; MERCAPTOALKYLGUANIDINE DERIVATIVE; NITRIC OXIDE SYNTHASE INHIBITOR; PLACEBO; PROSTAGLANDIN E2; REACTIVE NITROGEN SPECIES; SCAVENGER; UNCLASSIFIED DRUG; 2-MERCAPTOETHYLGUANIDINE; BIS(2 GUANIDINOETHYL) DISULFIDE; BIS(2-GUANIDINOETHYL)DISULFIDE; ENZYME INHIBITOR; GUANIDINE DERIVATIVE;

ANALYSIS OF VARIANCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BLEEDING TENDENCY; DIETARY INTAKE; DOG; DOSE RESPONSE; DRUG EFFICACY; DRUG SAFETY; FEMALE; GEL; GINGIVITIS; KRUSKAL WALLIS TEST; MAXIMUM TOLERATED DOSE; NONHUMAN; PERIODONTAL DISEASE; PREVENTIVE DENTISTRY; RANDOMIZATION; SCAVENGING SYSTEM; SCORING SYSTEM; TOOTH BRUSHING; TOOTH PLAQUE; WEIGHT REDUCTION; ANIMAL; DRUG ANTAGONISM; ENZYMOLOGY; NONPARAMETRIC TEST; PERIODONTICS; TOPICAL DRUG ADMINISTRATION;

ADMINISTRATION, TOPICAL; ANALYSIS OF VARIANCE; ANIMALS; DENTAL PLAQUE INDEX; DOGS; ENZYME INHIBITORS; FEMALE; FREE RADICAL SCAVENGERS; GELS; GINGIVITIS; GUANIDINES; NITRIC OXIDE SYNTHASE TYPE II; PERIODONTAL INDEX; RANDOM ALLOCATION; REACTIVE NITROGEN SPECIES; STATISTICS, NONPARAMETRIC;

EID: 33646347661     PISSN: 00223492     EISSN: None     Source Type: Journal    
DOI: 10.1902/jop.2006.050049     Document Type: Article

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