Increased sensitivity of glycogen synthesis to phosphorylase-a and impaired expression of the glycogen-targeting protein R6 in hepatocytes from insulin-resistant Zucker fa/fa rats

FEBS Journal

Volumn 273, Issue 9, 2006, Pages 1989-1999

  Arden, Catherine ^a   Green, Andrew R ^a   Hampson, Laura J ^a   Aiston, Susan ^a   Härndahl, Linda ^a   Greenberg, Cynthia C ^b   Brady, Matthew J ^b   Freeman, Susan ^c   Poucher, Simon M ^c   Agius, Loranne ^a  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

^b UNIVERSITY OF CHICAGO   (United States)

^c ASTRAZENECA   (United Kingdom)

Author keywords

Glycogen; Glycogen synthesis; Glycogen targeting proteins; Metabolic control analysis; Phosphorylase

Indexed keywords

GENE PRODUCT; GLUCOSE; GLYCOGEN; GLYCOGEN PHOSPHORYLASE; GLYCOGEN TARGETING PROTEIN R6; INSULIN; LEPTIN; LEPTIN RECEPTOR; PROTEIN GL; PROTEIN TARGETING TO GLYCOGEN PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; FEMALE; GLYCOGEN SYNTHESIS; INSULIN RESISTANCE; LIVER CELL; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RAT STRAIN;

ANIMALS; CARRIER PROTEINS; CELLS, CULTURED; DIABETES MELLITUS, TYPE 2; DISEASE MODELS, ANIMAL; FEMALE; GLYCOGEN; HEPATOCYTES; INSULIN; INSULIN RESISTANCE; LEPTIN; MALE; OBESITY; PHOSPHOPROTEIN PHOSPHATASE; PHOSPHORYLASE A; PROTEIN SUBUNITS; RATS; RATS, WISTAR; RATS, ZUCKER; RECEPTORS, CELL SURFACE;

ANIMALIA; RATTUS NORVEGICUS;

EID: 33646267691     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2006.05215.x     Document Type: Article

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