Targeted inhibition of Ca2+/calmodulin signaling exacerbates the dystrophic phenotype in mdx mouse muscle

Human Molecular Genetics

Volumn 15, Issue 9, 2006, Pages 1423-1435

  Chakkalakal, Joe V ^a   Michel, Stephanie A ^b   Chin, Eva R ^c   Michel, Robin N ^b   Jasmin, Bernard J ^a,d  

^a UNIVERSITY OF OTTAWA   (Canada)

^b Gina Cody School of Engineering and Computer Science   (Canada)

^c PFIZER INC   (United States)

^d OTTAWA HOSPITAL RESEARCH INSTITUTE   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CALCINEURIN; CALCIUM ION; CALMODULIN; CALMODULIN BINDING PROTEIN; MESSENGER RNA; MYOCYTE ENHANCER FACTOR 2; MYOSIN HEAVY CHAIN; NUCLEAR FACTOR; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; TROPONIN I; UTROPHIN; CALCIUM;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CROSS BREEDING; DISEASE COURSE; DISEASE EXACERBATION; DRUG TARGETING; DUCHENNE MUSCULAR DYSTROPHY; MOUSE; MOUSE STRAIN; MUSCULAR DYSTROPHY; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DEFICIENCY; PROTEIN EXPRESSION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; SLOW MUSCLE FIBER; SOLEUS MUSCLE; TRANSGENIC MOUSE; ANIMAL; CALCIUM SIGNALING; DRUG ANTAGONISM; FEMALE; GENETICS; MALE; METABOLISM; PATHOLOGY; PHYSIOLOGY; SKELETAL MUSCLE; X CHROMOSOME LINKED MUSCULAR DYSTROPHIC MOUSE;

ANIMALIA; MUS MUSCULUS;

ANIMALS; CALCIUM; CALCIUM SIGNALING; CALMODULIN; CALMODULIN-BINDING PROTEINS; DISEASE PROGRESSION; FEMALE; MALE; MICE; MICE, INBRED MDX; MICE, TRANSGENIC; MUSCLE FIBERS, SLOW-TWITCH; MUSCLE, SKELETAL; MUSCULAR DYSTROPHY, DUCHENNE;

EID: 33646176985     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddl065     Document Type: Article

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