The calcineurin-NFAT pathway and muscle fiber-type gene expression

American Journal of Physiology - Cell Physiology

Volumn 279, Issue 4 48-4, 2000, Pages

  Swoap, Steven J ^a   Hunter, R Bridge ^b   Stevenson, Eric J ^b   Felton, Heather Mitchell ^b   Kansagra, Nilesh V ^a   Lang, Joshua M ^c   Esser, Karyn A ^c   Kandarian, Susan C ^b  

^a WILLIAMS COLLEGE   (United States)

^b BOSTON UNIVERSITY   (United States)

^c UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

Fast twitch muscle; Myosin heavy chain; Myosin light chain; Nuclear factor of activated T cells; SERCA1; Slow twitch muscle

Indexed keywords

CALCINEURIN; MYOSIN HEAVY CHAIN; MYOSIN LIGHT CHAIN; NUCLEAR FACTOR; OLIGONUCLEOTIDE; TRANSCRIPTION FACTOR;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FAST MUSCLE; GENE EXPRESSION REGULATION; GENE OVEREXPRESSION; MUSCLE CELL; MYOTUBE; NONHUMAN; NUCLEOTIDE SEQUENCE; PLASMID; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; RAT; SLOW MUSCLE; SOLEUS MUSCLE; TRANSCRIPTION INITIATION;

ANIMALIA; MAMMALIA;

EID: 0033679578     PISSN: 03636143     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpcell.2000.279.4.c915     Document Type: Article

References (42)

1. Activation and cellular localization of the cyclosporine A-sensitive transcription factor NF-AT in skeletal muscle cells
2. Nuclear localization of NF-ATc by a calcineurin-dependent, cyclosporin-sensitive intramolecular interaction
3. Cellular adaptations of skeletal muscles to cyclosporine
4. 2+- and stimulus duration-dependent switch for hippocampal gene expression
5. Extraction of nuclear proteins from striated muscle tissue
6. Muscle plasticity: Energy demand/ supply processes
7. Fiber-type-specific transcription of the troponin I slow gene is regulated by multiple elements
8. A calcineurin-dependent transcriptional pathway controls skeletal muscle fiber type
9. Delineation of a slow-twitch-myofiber-specific transcriptional element by using in vivo somatic gene transfer
10. Calcineurin is required for skeletal muscle hypertrophy
11. Characterization of antigen receptor response elements within the interleukin-2 enhancer
12. The CACC box and myocyte enhancer factor-2 sites within the myosin light chain 2 slow promoter cooperate in regulating nerve-specific transcription in skeletal muscle
13. Analysis of protein-DNA interactions
14. p53 transactivation of the HIV-1 long terminal repeat is blocked by PD 144795, a calcineurin-inhibitor with anti-HIV properties
15. Regulatory role of MEF2D in serum induction of the c-jun promoter
16. Cyclosporin A decreases rat skeletal muscle mitochondrial respiration in vitro
17. Correlations between MyoD, myogenin, SERCA1, SERCA2 and phospholamban transcripts during transformation of type-II to type-I skeletal muscle fibers
18. Myogenin induces a shift of enzyme activity from glycolytic to oxidatire metabolism in muscles of transgenic mice
19. MyoD protein is differentially accumulated in fast and slow skeletal muscle fibres and required for normal fibre type balance in rodents
20. Selective accumulation of MyoD and myogenin mRNAs in fast and slow adult skeletal muscle is controlled by innervation and hormones
21. PGAM-M expression is regulated pretranslationally in hindlimb muscles and under altered loading conditions
22. Quantification of MyoD, myogenin, MRF4 and Id-1 by reverse-transcriptase polymerase chain reaction in rat muscles: Effects of hypothyroidism and chronic low-frequency stimulation
23. Cyclosporin A-sensitive induction of the Epstein-Barr virus lytic switch is mediated via a novel pathway involving a MEF2 family member
24. Expression of NFAT-family proteins in normal human T cells
25. The role of NFATp in cyclosporin A-sensitive tumor necrosis factor-alpha gene transcription
26. Effects of cyclosporine A on skeletal muscle mitochondrial respiration and endurance time in rats
27. Normalization of muscle plasmid uptake by Southern blot: Application to SERCA1 promoter analysis
28. Increase of skeletal muscle relaxation speed by direct injection of parvalbumin cDNA
29. IGF-1 induces skeletal myocyte hypertrophy through calcineurin in association with GATA-2 and NF-ATc1
30. FK-506- and CsA-sensitive activation of the interleukin-2 promoter by calcineurin
31. Transcription factors of the NFAT family: Regulation and function
32. 2+-dependent calcineurin signalling pathway
33. In vivo analysis of the myosin heavy chain IIB promoter region
34. A possible regulatory role for conserved promoter motifs in an adult-specific muscle myosin gene from mouse
35. Stimulation of Elk1 transcriptional activity by mitogen-activated protein kinases is negatively regulated by protein phosphatase 2B (calcineurin)
36. Redundant expression but selective utilization of nuclear factor of activated T cells family members
37. Differential expression of muscle regulatory factor genes in normal and denervated adult rat hindlimb muscles
38. An E-box within the MHC IIB gene is bound by MyoD and is required for gene expression in fast muscle
39. Regulation of the Nur77 orphan steroid receptor in activation-induced apoptosis
40. 2+-ATPase isoforms in rat muscles
41. Cytochrome c promoter activity in soleus and white vastus lateralis muscles in rats
42. NF-AT activation requires suppression of Crm1-dependent export by calcineurin