Calcineurin is a potent regulator for skeletal muscle regeneration by association with NFATc1 and GATA-2

Acta Neuropathologica

Volumn 105, Issue 3, 2003, Pages 271-280

  Sakuma, Kunihiro ^a   Nishikawa, Junji ^a   Nakao, Ryuta ^a   Watanabe, Kimi ^b   Totsuka, Tsuyoshi ^b   Nakano, Hiroshi ^c   Sano, Mamoru ^a   Yasuhara, Masahiro ^a  

^a KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

^b INSTITUTE FOR DEVELOPMENTAL RESEARCH   (Japan)

^c NAKAMURA GAKUEN UNIVERSITY   (Japan)

Author keywords

Calcineurin; Muscle regeneration; MyoD; NFATc1; Satellite cell

Indexed keywords

BROXURIDINE; BUFFER; BUPIVACAINE; CALCINEURIN; CALCIUM; CYCLOSPORIN A; MUSCLE PROTEIN; MYOD PROTEIN; MYOGENIC FACTOR 5; MYOGENIN; PHOSPHATASE; PHOSPHATE; SODIUM CHLORIDE; TRANSCRIPTION FACTOR GATA 3; TRANSCRIPTION FACTOR NFAT; UNCLASSIFIED DRUG; DNA BINDING PROTEIN; GATA2 PROTEIN, MOUSE; GATA2 PROTEIN, RAT; LOCAL ANESTHETIC AGENT; NFATC1 PROTEIN, MOUSE; NUCLEAR PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR GATA 2;

ANIMAL TISSUE; ARTICLE; CALCIFICATION; CELL MEMBRANE; CELL PROLIFERATION; CONNECTIVE TISSUE; CONTROLLED STUDY; CYTOSOL; ENZYME REGULATION; EXTRACELLULAR SPACE; IMMATURITY; IMMUNOREACTIVITY; INFLAMMATION; MACROPHAGE; MALE; MOUSE; MUSCLE ATROPHY; MUSCLE FIBRIL; MUSCLE HYPERTROPHY; MUSCLE INJURY; MUSCLE REGENERATION; MYOBLAST; MYOTUBE; NONHUMAN; PRECIPITATION; PRIORITY JOURNAL; PROTEIN DEPHOSPHORYLATION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RAT; SATELLITE CELL; SIGNAL TRANSDUCTION; SKELETAL MUSCLE; TIBIALIS ANTERIOR MUSCLE; ANIMAL; DRUG EFFECT; IMMUNOHISTOCHEMISTRY; INTRAMUSCULAR DRUG ADMINISTRATION; INTRAPERITONEAL DRUG ADMINISTRATION; METABOLISM; PATHOLOGY; PHYSIOLOGY; REGENERATION; SERODIAGNOSIS; SKELETAL MUSCLE SATELLITE CELL; WESTERN BLOTTING;

ANESTHETICS, LOCAL; ANIMALS; BLOTTING, WESTERN; BUPIVACAINE; CALCINEURIN; DNA-BINDING PROTEINS; GATA2 TRANSCRIPTION FACTOR; IMMUNOHISTOCHEMISTRY; INJECTIONS, INTRAMUSCULAR; INJECTIONS, INTRAPERITONEAL; MALE; MICE; MUSCLE, SKELETAL; MYOD PROTEIN; NFATC TRANSCRIPTION FACTORS; NUCLEAR PROTEINS; PRECIPITIN TESTS; RATS; REGENERATION; SATELLITE CELLS, SKELETAL MUSCLE; TRANSCRIPTION FACTORS;

EID: 0038236734     PISSN: 00016322     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00401-002-0647-0     Document Type: Article

References (42)

1. Abbott KL, Friday BB, Thaloor D, Murphy TJ, Pavlath GK (1998) Activation and cellular localization of the cyclosporine A-sensitive transcription factor NF-AT in skeletal muscle cells. Mol Biol Cell 9:2905-2916
2. Beauchamp JR, Heslop L, Yu DSW, Tajbakhsh S, Kelly RG, Wernig A, Buckingham ME, Partridge TA, Zammit PS (2000) Expression of CD34 and Myf5 defines the majority of quiescent adult skeletal muscle satellite cells. J Cell Biol 151:1221-1233
3. Bischoff R (1994) The satellite cell and muscle regeneration. In: Engel AG, Armstrong F (eds) Myology. McGraw-Hill, New York, pp 97-118
4. Calvo S, Venepally P, Cheng J, Buonanno A (1999) Fiber-type-specific transcription of the troponin I slow gene is regulated by multiple elements. Mol Cell Biol 19:515-525
5. Chakravarthy MV, Abraha TW, Schwartz RJ, Fiorotto ML, Booth FW (2000) Insulin- like growth factor-I extends in vitro replicative life span of skeletal muscle satellite cells by enhancing G1/S cell cycle progression via the activation of phosphatidylinositol 3′-kinase/Akt signaling pathway. J Biol Chem 275:35942-35952
6. 2+ concentration during constant 10 Hz stimulation of mouse single fibers. Physiologist 39:A75
7. Chin ER, Olson EN, Richardson JA, Yang Q, Humphries C, Shelton JM, Wu H, Zhu W, Bassel-Duby R, Williams RS (1998) A calcineurin-dependent transcriptional pathway controls skeletal muscle fiber type. Genes Dev 12:2499-2509
8. Coleman ME, Demayo F, Yin KC, Lee HM, Geske R, Montgomery C, Schwartz RJ (1995) Myogenic vector expression of insulin-like growth factor I stimulates muscle cell differentiation and myofiber hypertrophy in transgenic mice. J Biol Chem 270:12109-12116
9. Conboy IM, Manoli D, Mhaiskar V, Jones PP (1999) Calcineurin and vacuolar-type H+-ATPase modulate macrophage effector functions. Proc Natl Acad Sci USA 96:6324-6329
10. deFazio A, Leary JA, Hedley DW, Tattersal MH (1987) Immunohistochemical detection of proliferating cells in vivo. J Histochem Cytochem 35:571-577
11. Delling U, Tureckova J, Lim HW, De Windt LJ, Rotwein P, Molkentin JD (2000) A calcineurin-NFATc3-dependent pathway regulates skeletal muscle differentiation and slow myosin heavy-chain expression. Mol Cell Biol 20:6600-6611
12. DeVol DL, Rotwein P, Levis Sadow J, Npvakofski J, Bechtel PJ (1990) Activation of insulin-like growth factor gene expression during work-induced skeletal muscle growth. Am J Physiol 259:E89-E95
13. Dunn SE, Burns JL, Michel RN (1999) Calcineurin is required for skeletal muscle hypertrophy. J Biol Chem 274:21908-21912
14. Dunn SE, Chin ER, Michel RN (2000) Matching of calcineurin activity to upstream effectors is critical for skeletal muscle fiber growth. J Cell Biol 151:663-672
15. Engert JC, Berglund EB, Rosenthal N (1996) Proliferation precedes differentiation in IGF-I-stimulated myogenesis. J Cell Biol 135:431-440
16. Friday BB, Pavlath GK (2001) A calcineurin-and NFAT-dependent pathway regulates Myf-5 gene expression in skeletal muscle reserve cells. J Cell Sci 114:303-310
17. Friday BB, Horsley V, Pavlath GK (2000) Calcineurin activity is required for the initiation of skeletal muscle differentiation. J Cell Biol 149:657-665
18. Hawke TJ, Garry DJ (2001) Myogenic satellite cells: physiology to molecular biology. J Appl Physiol 91:534-551
19. Horsley V, Friday BB, Matteson S, Kegley KM, Gephart J, Pavlath GK (2001) Regulation of the growth of multinucleated muscle cells by an NFATC2-dependent pathway. J Cell Biol 153:329-338
20. Jennische E, Matejka GL (1992) IGF-I binding and IGF-I expression in regenerating skeletal muscle. Acta Physiol Scand 146:79-86
21. Kaye D, Pimental D, Prasad S, Maki T, Berger HJ, McNeil PL, Smith TW, Kelly RA (1996) Role of transiently altered sarcolemmal membrane permeability and basic fibroblast growth factor release in the hypertrophic response of adult rat ventricular myocytes to increased mechanical activity in vitro. J Clin Invest 97:281-291
22. Kurek JB, Nouri S, Kannourakis G, Murphy M, Lawrence A (1996) Leukemia inhibitory factor and interleukin-6 are produced by diseased and regenerating skeletal muscle. Muscle Nerve 19:1291-1301
23. McNeil PL, Steinhardt RA (1997) Loss, restoration, and maintenance of plasma membrane integrity. J Cell Biol 137:1-4
24. Megeney LA, Kablar B, Garrett K, Anderson JE, Rudnicki MA (1996) MyoD is required for myogenic stem cell function in adult skeletal muscle. Genes Dev 10:1173-1183
25. Mende U, Kagen A, Cohen A, Aramburu J, Schoen FJ, Neer EJ (1998) Transient cardiac expression of constitutively active Galphaq leads to hypertrophy and dilated cardiomyopathy by calcineurin-dependent and independent pathways. Proc Natl Acad Sci USA 95:13893-13898
26. Merly F, Lescaudron L, Rouaud T, Crossin F, Gardahaut MF (1999) Macrophages enhance muscle satellite cell proliferation and delay their differentiation. Muscle Nerve 22:724-732
27. Molkentin JD, Lu, J-R, Antos CL, Markham B, Richardson J, Robbins J, Grant SR, Olson EN (1998) A calcineurin-dependent transcriptional pathway for cardiac hypertrophy. Cell 93: 215-228
28. Musaró A, McCullagh KJA, Naya FJ, Olson EN, Rosenthal N (1999) IGF-I induces skeletal myocyte hypertrophy through calcineurin in association with GATA-2 and NF-ATc1. Nature 40:581-585
29. Musaró A, McCullagh K, Paul A, Houghton L, Dobrowolony G, Molinaro M, Barton ER, Sweeney HL, Rosenthal N (2001) Localized Igf-1 transgene expression sustains hypertrophy and regeneration in senescent skeletal muscle. Nat Genet 27:195-200
30. Naya FJ, Mercer B, Shelton J, Richadson JA, Williams RS, Olson EN (2000) Stimulation of slow skeletal muscle fiber gene expression by calcineurin in vivo. J Biol Chem 275:4545-4548
31. Pimorady-Esfahani A, Grounds MD, McMenamin PG (1997) Macrophages and dendritic cells in normal and regenerating murine skeletal muscle. Muscle Nerve 20:158-166
32. Sabourin LA, Girgis-Gabardo A, Seale P, Asakura A, Rudnicki MA (1999) Reduced differentiation potential of primary MyoD-/-cells derived from adult skeletal muscle. J Cell Biol 144:631-643
33. Sakuma K, Watanabe K, Totsuka T, Uramoto I, Sakamoto K, Sano M (1998) Differential adaptations of insulin-like growth factor, basic fibroblast growth factor and leukemia inhibitory factor in the plantaris muscle of rats by mechanical overloading: an immunohistochemical study. Acta Neuropathol 95: 123-130
34. Sakuma K, Watanabe K, Sano M, Sakamoto K, Uramoto I, Totsuka T (1999) The adaptive response of MyoD family protein in the overloaded, regenerating and denervated rat muscles. Biochim Biophys Acta 1428:284-292
35. Sakuma K, Watanabe K, Sano M, Sakamoto K, Uramoto I, Totsuka T (2000) The adaptive response of transforming growth factor-β2 and βRII in the overloaded, regenerating and denervated muscles of rats. Acta Neuropathol 99:177-185
36. Sakuma K, Watanabe K, Sano M, Uramoto I, Totsuka T (2000) Differential adaptation of growth and differentiation factor 8/myostatin, fibroblast growth factor 6 and leukemia inhibitory factor in overloaded, regenerating and denervated rat muscles. Biochim Biophys Acta 1497:77-88
37. Sakuma K, Watanabe K, Sano M, Uramoto I, Nakano H, Li Y-J, Kaneda S, Sorimachi Y, Yoshimoto K, Yasuhara M, Totsuka T (2001) A possible role for BDNF, NT-4 and TrkB in the spinal cord and muscle of rat subjected to mechanical overload, bupivacaine injection and axotomy. Brain Res 907:1-19
38. 2+-dependent calcineurin signalling pathway. Nature 40:576-581
39. Sussman MA, Lim HW, Gude N, Taigen T, Olson EN, Robbins J, Colbert MC, Gualberto A, Wieczorek DF, Molkentin JD (1998) Prevention of cardiac hypertrophy in mice by calcineurin inhibition. Science 281:1690-1693
40. Tamaki T, Akatsuka A, Tokunaga M, Ishige K, Uchiyama S, Shiraishi T (1997) Morphological and biochemical evidence of muscle hyperplasia following weight-lifting exercise in rats. Am J Physiol 273:C246-C256
41. Torgan CE, Daniels MP (2001) Regulation of myosin heavy chain expression during rat skeletal muscle development in vitro. Mol Biol Cell 12:1499-1508
42. Westerblad H, Allen DG (1991) Changes in myoplasmic calcium concentration during fatigue in single mouse muscle fibers. J Gen Physiol 98:615-635