Up-regulation of interleukin-4 production via NF-AT/AP-1 activation in T cells by biochanin A, a phytoestrogen and its metabolites

Toxicology and Applied Pharmacology

Volumn 212, Issue 3, 2006, Pages 188-199

  Park, Jin ^a   Chung, Su Wol ^b   Kim, Seung Hyun ^a   Kim, Tae Sung ^a  

^a Korea University   (South Korea)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

Allergy; AP 1; Biochanin A; Interleukin 4; NF AT; T cell

Indexed keywords

4 ETHYLPHENOL; BIOCHANIN A; CD4 ANTIGEN; DRUG METABOLITE; GENISTEIN; INTERLEUKIN 4; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; MITOGEN ACTIVATED PROTEIN KINASE P38 INHIBITOR; PHLOROGLUCINOLCARBOXYLIC ACID; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PHYTOESTROGEN; PROTEIN KINASE C; PROTEIN KINASE C INHIBITOR; TRANSCRIPTION FACTOR AP 1; TRANSCRIPTION FACTOR NFAT;

ALLERGY; ANIMAL CELL; ARTICLE; BINDING SITE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DNA BINDING; DOSE RESPONSE; DRUG EFFECT; ENZYME ACTIVITY; GENE ACTIVITY; GENE DELETION; GENETIC TRANSFECTION; IMMUNE RESPONSE; LYMPHOMA CELL; MOUSE; NONHUMAN; PROMOTER REGION; PROTEIN PHOSPHORYLATION; T LYMPHOCYTE; TRANSCRIPTION INITIATION; UPREGULATION;

CD4-POSITIVE T-LYMPHOCYTES; CELL LINE, TUMOR; DNA; DNA-BINDING PROTEINS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; GENISTEIN; HUMANS; INTERLEUKIN-4; LYMPHOCYTE ACTIVATION; LYMPHOMA; NFATC TRANSCRIPTION FACTORS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHENOLS; PHOSPHORYLATION; PHYTOESTROGENS; RNA, MESSENGER; TRANSCRIPTION FACTOR AP-1; TRANSFECTION; UP-REGULATION;

ANIMALIA;

EID: 33646159284     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2005.08.001     Document Type: Article

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