Age-associated cellular relocation of Sod 1 as a self-defense is a futile mechanism to prevent vascular aging

Biochemical and Biophysical Research Communications

Volumn 344, Issue 3, 2006, Pages 972-980

  van der Loo, Bernd ^a   Bachschmid, Markus ^b   Skepper, Jeremy N ^c   Labugger, Ralf ^d   Schildknecht, Stefan ^b   Hahn, Raphael ^b   Müssig, Elisabeth ^b   Gygi, Daniel ^d   Lüscher, Thomas F ^a,d  

^a UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^b UNIVERSITY OF KONSTANZ   (Germany)

^c UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^d UNIVERSITY OF ZURICH   (Switzerland)

Author keywords

Aging; Mitochondria; Reactive oxygen species; SOD

Indexed keywords

PROTEIN; PROTEIN SOD 1; UNCLASSIFIED DRUG;

AGING; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CARDIOVASCULAR RISK; CELL ACTIVITY; CONTROLLED STUDY; CYTOSOL; DETOXIFICATION; GENE TARGETING; MALE; MITOCHONDRION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; RISK FACTOR; VASCULARIZATION;

AGING; ANIMALS; AORTA; CYTOPROTECTION; MALE; OXIDATIVE STRESS; RATS; SUBCELLULAR FRACTIONS; SUPEROXIDE DISMUTASE; TISSUE DISTRIBUTION;

ANIMALIA;

EID: 33646146937     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2006.03.224     Document Type: Article

References (40)

1. Finkel T., and Holbrook N.J. Oxidants, oxidative stress and the biology of ageing. Nature 408 (2000) 239-247
2. Hamilton C.A., Brosnan M.J., McIntyre M., Graham D., and Dominiczak A.F. Superoxide excess in hypertension and aging: a common cause of endothelial dysfunction. Hypertension 37 (2001) 529-534
3. Tschudi M., Barton M., Bersinger N.A., Moreau P., Cosentino F., Noll G., Malinski T., and Lüscher T.F. Effect of age on kinetics of nitric oxide release in rat aorta and pulmonary artery. J. Clin. Invest. 98 (1996) 899-905
4. Yan L.J., Levine R.L., and Sohal R.S. Oxidative damage during aging targets mitochondrial aconitase. Proc. Natl. Acad. Sci. USA 94 (1997) 11168-11172
5. Beckman K.B., and Ames B.N. Mitochondrial aging: open questions. Ann. NY Acad. Sci. 854 (1998) 118-127
6. Kokoszka J.E., Coskun P., Esposito L., and Wallace D.C. Increased mitochondrial oxidative stress in the Sod2 (+/-) mouse results in the age-related decline of mitochondrial function culminating in increased apoptosis. Proc. Natl. Acad. Sci. USA 98 (2001) 2278-2283
7. van der Loo B., and Lüscher T.F. Endothelium-mediated signaling and vascular aging. In: Hagen T. (Ed). Mechanisms of Cardiovascular Aging. Advances in Cell Aging and Gerontology (2002), Elsevier Science, Amsterdam, The Netherlands 127-144
8. Stralin P., Karlsson K., Johansson B.O., and Marklund S.L. The interstitium of the human arterial wall contains very large amounts of extracellular superoxide dismutase. Arterioscler. Thromb. Vasc. Biol. 15 (1995) 2032-2036
9. Philips J.P., Campbell S.D., Michaud D., Charbonneau M., and Hilliker A.J. Null mutation of copper/zinc superoxide dismutase in Drosophila confers hypersensitivity to paraquat and reduced longevity. Proc. Natl. Acad. Sci. USA 86 (1989) 2761-2765
10. Reaume A.G., Elliott J.L., Hoffman E.K., Kowall N.W., Ferrante R.J., Siwek D.F., Wilcox H.M., Flood D.G., Flint Beal M., Brown Jr. R.H., Scott R.W., and Snider W.D. Motor neurons in Cu/Zn superoxide dismutase-deficient mice develop normally, but exhibit enhanced cell death after axonal injury. Nat. Genet. 13 (1996) 43-47
11. Didion S.P., Ryan M.J., Didion L.A., Fegan P.E., Sigmund C.D., and Faraci F.M. Increased superoxide and vascular dysfunction in CuZnSOD-deficient mice. Circ. Res. 91 (2002) 938-944
12. Cooke C.L., and Davidge S.T. Endothelial-dependent vasodilation is reduced in mesenteric arteries from superoxide dismutase knockout mice. Cardiovasc. Res. 60 (2003) 635-642
13. Weisiger R.A., and Fridovich I. Superoxide dismutase. Organelle specificity. J. Biol. Chem. 248 (1973) 3582-3592
14. Okado-Matsumoto A., and Fridovich I. Subcellular distribution of superoxide dismutases (SOD) in rat liver. J. Biol. Chem. 276 (2001) 38388-38393
15. Sturtz-Field L.A., Furukawa Y., O'Halloran T.V., and Culotta V.C. Factors controlling the uptake of yeast copper/zinc superoxide dismutase into mitochondria. J. Biol. Chem. 278 (2003) 28052-28059
16. Sturtz L.A., Dieckert K., Jensen L.T., Lill R., and Culotta V.C. A fraction of yeast Cu,Zn-superoxide dismutase and its metallochaperone, CCS, localize to the intermembrane space of mitochondria. A physiological role for SOD1 in guarding against mitochondrial oxidative damage. J. Biol. Chem. 276 (2001) 38084-38089
17. m for hydrogen peroxide. Proc. Natl. Acad. Sci. USA 93 (1996) 5709-5714
18. Mattiazzi M., d'Aurelio M., Gajewski C.D., Martushova K., Kiali M., Beal F., and Manfredi G. Mutated human SOD1 causes dysfunction of oxidative phosphorylation in mitochondria of transgenic mice. J. Biol. Chem. 277 (2002) 29626-29633
19. Higgins C.M.J., Jung C., Ding H., and Xu Z. Mutant Cu, Zn superoxide dismutase that causes motoneuron degeneration is present in mitochondria in the CNS. J. Neurosci. 22 (2002) 1-6
20. Higgins C.M.J., Jung C., and Xu Z. ALS-associated mutant SOD1G93A causes mitochondrial vacuolation by expansion of the intermembrane space and by involvement of SOD1 aggregation and peroxisomes. BMC Neurosci. 4 (2003) 16
21. Vijayvergiya C., Beal M.F., Buck J., and Manfredi G. Mutant superoxide dismutase 1 forms aggregates in the brain mitochondrial matrix of amyotrophic lateral sclerosis mice. J. Neurosci. 25 (2005) 2463-2470
22. Gyllenhammer H. Lucigenin chemiluminescence in the assessment of neutrophil superoxide production. J. Immunol. Methods 97 (1987) 209-213
23. van der Loo B., Labugger R., Aebischer C.P., Skepper J.N., Bachschmid M., Spitzer V., Kilo J., Altwegg L., Ullrich V., and Lüscher T.F. Cardiovascular aging is associated with vitamin E increase. Circulation 105 (2002) 1635-1638
24. Oury T.D., Day B.J., and Crapo J.D. Extracellular superoxide dismutase in vessels and airways of humans and baboons. Free Radic. Med. Biol. 20 (1996) 957-965
25. Orr W., and Sohal R.S. Extended life-span by overexpression of superoxide dismutase and catalase in Drosophila melanogaster. Science 263 (1994) 1128-1130
26. Parkes T.L., Elia A.J., Dickinson D., Hilliker A.J., Phillips J.P., and Boulianne G.L. Extension of Drosophila life-span by overexpression of human sod 1 in motoneurons. Nat. Genet. 19 (1998) 171-174
27. Orr W., Mockett R.J., Benes J.J., and Sohal R.S. Effects of overexpression of copper-zinc and manganese superoxide dismutases, catalase, and thioredoxin reductase genes on longevity in Drosophila melanogaster. J. Biol. Chem. 278 (2003) 26418-26422
28. Huang T.T., Carlson E.J., Gillespie A.M., Shi Y., and Epstein C.J. Ubiquitous overexpression of CuZn superoxide dismutase does not extend life span in mice. J. Gerontol. A Biol. Sci. Med. Sci. 55 (2000) B5-B9
29. Faraci F.M., and Didion S.P. Vascular protection: superoxide dismutase isoforms in the vessel wall. Arterioscl. Thromb. Vasc. Biol. 24 (2004) 1367-1373
30. Otsu K., Ikeda Y., and Fujii J. Accumulation of manganese superoxide dismutase under metal-depleted conditions: proposed role for zinc ions in cellular redox balance. Biochem. J. 377 (2004) 241-248
31. Papapetropoulos A., Rudic R.D., and Sessa W.C. Molecular control of nitric oxide synthases in the cardiovascular system. Cardiovasc. Res. 43 (1999) 509-520
32. van der Loo B., and Martin J.F. The adventitia, endothelium, and atherosclerosis. Int. J. Microcirc. 17 (1997) 280-288
33. Kim B.Y., Han M.J., and Chung A.S. Effects of reactive oxygen species on proliferation of Chinese hamster lung fibroblast (V79) cells. Free Radic. Biol. Med. 30 (2001) 686-698
34. van der Loo B., Labugger R., Skepper J.N., Bachschmid M., Kilo J., Powell J.M., Palacios-Callender M., Erusalimsky J.D., Quaschning T., Malinski T., Gygi D., Ullrich V., and Lüscher T.F. Enhanced peroxynitrite formation is associated with vascular aging. J. Exp. Med. 192 (2000) 1731-1743
35. Keller G.A., Warner T.G., Steimer K.S., and Hallewell R.A. Cu,Zn superoxide dismutase is a peroxisomal enzyme in human fibroblasts and hepatoma cells. Proc. Natl. Acad. Sci. USA 88 (1991) 7381-7385
36. Rogers R.J., Monnier J.M., and Nick H.S. Tumor necrosis factor-alpha selectively induces MnSOD expression via mitochondria-to-nucleus signaling, whereas interleukin-1beta utilizes an alternative pathway. J. Biol. Chem. 276 (2001) 20419-20427
37. Beckman J.S., Ischiropoulos H., Zhu L., van der Woerd M., Smith C., Chen J., Harrison J., Martin J.C., and Tsai M. Kinetics of superoxide dismutase- and iron-catalyzed nitration of phenolics by peroxynitrite. Arch. Biochem. Biophys. 298 (1992) 438-445
38. Goldstein S., Czapski G., Lind J., and Merenyi G. Tyrosine nitration by simultaneous generation of NO and multiscripts(O, 2, mml:none(), mml:none(), -) under physiological conditions. How the radicals do the job. J. Biol. Chem. 275 (2000) 3031-3036
39. Aulak K.S., Koeck T., Crabb J.W., and Stuehr D.J. Dynamics of protein nitration in cells and mitochondria. Am. J. Physiol. Heart Circ. Physiol. 286 (2004) H30-H38
40. Maftah A., Ratinaud M.H., Dumas M., Bonte F., Meybeck A., and Julien R. Human epidermal cells progressively lose their cardiolipins during ageing without change in mitochondrial transmembrane potential. Mech. Ageing Dev. 77 (1994) 83-96