Validation of a mouse model of chemical-induced asthma using trimellitic anhydride, a respiratory sensitizer, and dinitrochlorobenzene, a dermal sensitizer

Journal of Allergy and Clinical Immunology

Volumn 117, Issue 5, 2006, Pages 1090-1097

  Vanoirbeek, Jeroen A J ^a   Tarkowski, Maciej ^a,b   Vanhooren, Hadewijch M ^a   De Vooght, Vanessa ^a   Nemery, Benoit ^a   Hoet, Peter H M ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

^b NOFER INSTITUTE OF OCCUPATIONAL MEDICINE   (Poland)

Author keywords

1 chloro 2; 4 dinitrobenzene; IFN ; IL 4; macrophage inflammatory protein 2; murine model; occupational asthma; T lymphocytes subtypes; TNF ; Trimellitic anhydride

Indexed keywords

1 CHLORO 2,4 DINITROBENZENE; CD19 ANTIGEN; CONCANAVALIN A; GAMMA INTERFERON; IMMUNOGLOBULIN E; INTERLEUKIN 4; MACROPHAGE INFLAMMATORY PROTEIN 1; MACROPHAGE INFLAMMATORY PROTEIN 2; METHACHOLINE; TRIMELLITIC ANHYDRIDE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASTHMA; B LYMPHOCYTE; BODY PLETHYSMOGRAPHY; CELLULAR DISTRIBUTION; CERVICAL LYMPH NODE; CONTROLLED STUDY; IMMUNOGLOBULIN BLOOD LEVEL; INCUBATION TIME; LUNG LAVAGE; LUNG VENTILATION; LYMPH NODE CELL; LYMPHOCYTE; MALE; MOUSE; NEUTROPHIL; NONHUMAN; PHOTOREACTIVITY; PNEUMONIA; PRIORITY JOURNAL; RESPIRATORY FUNCTION; SENSITIZATION; SUPERNATANT; VALIDATION STUDY;

ALLERGENS; ANIMALS; ASTHMA; CYTOKINES; DINITROCHLOROBENZENE; DISEASE MODELS, ANIMAL; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G; IRRITANTS; LYMPH NODES; MALE; MICE; MICE, INBRED BALB C; PHTHALIC ANHYDRIDES; RESPIRATORY FUNCTION TESTS; TH1 CELLS; TH2 CELLS;

EID: 33646125186     PISSN: 00916749     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jaci.2006.01.027     Document Type: Article

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