Respiratory Allergy to Trimellitic Anhydride in Rats: Concentration-Response Relationships during Elicitation

Inhalation Toxicology

Volumn 16, Issue 5, 2004, Pages 259-269

  Arts, Josje H E ^a   De Koning, Martijn W ^a,b   Bloksma, Nanne ^b   Kuper, C Frieke ^a  

^a TNO   (Netherlands)

^b UTRECHT UNIVERSITY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

DRUG VEHICLE; IMMUNOGLOBULIN E; METHACHOLINE; TRIMELLITIC ANHYDRIDE;

AIRWAY DYNAMICS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BREATHING PATTERN; BREATHING RATE; CONCENTRATION RESPONSE; CONTROLLED STUDY; FEMALE; HISTOPATHOLOGY; IMMUNOGLOBULIN BLOOD LEVEL; INHALATION; LARYNX; LARYNX INJURY; LUNG; LUNG WEIGHT; NONHUMAN; PRIORITY JOURNAL; RAT; RESPIRATORY TRACT ALLERGY; SKIN SENSITIZATION; SQUAMOUS CELL METAPLASIA; TIDAL VOLUME; TRACHEA;

ADMINISTRATION, INHALATION; ALLERGENS; ANIMALS; BODY WEIGHT; BRONCHIAL PROVOCATION TESTS; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; IMMUNOGLOBULIN E; LUNG; METHACHOLINE CHLORIDE; NO-OBSERVED-ADVERSE-EFFECT LEVEL; ORGAN SIZE; PHTHALIC ANHYDRIDES; RATS; RATS, INBRED BN; RATS, WISTAR; RESPIRATORY FUNCTION TESTS; RESPIRATORY HYPERSENSITIVITY;

ANIMALIA; RATTUS NORVEGICUS;

EID: 2342644796     PISSN: 08958378     EISSN: None     Source Type: Journal    
DOI: 10.1080/08958370490427932     Document Type: Article

References (30)

1. Alarie, Y. 1973. Sensory irritation of the upper airways by airborne chemicals. Toxicol. Appl. Pharmacol. 24:279-297.
2. American Conference of Governmental Industrial Hygienists. 1999. TLVs® and other occupational exposure values. Cincinnati, OH. ACGIH.
3. Arakawa, H., Lötvall, J., Kawikova, I., Morikawa, A., Löfdahl, C.-G., and Skoogh, B.-E. 1995. Airway responses following intradermal sensitization to different types of allergens: Ovalbumin, trimellitic anhydride and dermatophagoides farinae. Int. Arch. Allergy Immunol. 108:274-280.
4. Arts, J. H. E. 2001. Respiratory allergy induced by low molecular weight chemicals in rats. PhD thesis, Utrecht University, Utrecht, The Netherlands.
5. Arts, J. H. E., Dröge, S. C. M., Spanhaak, S., Bloksma, N., Penninks, A. H., and Kuper, C. F. 1997. Local lymph node activation and IgE responses in BN and Wistar rats after dermal application of sensitizing and non-sensitizing chemicals. Toxicology 117:229-237.
6. Arts, J. H. E., Kuper, C. F., Spoor, S. M., and Bloksma, N. 1998. Airway morphology and function of rats following dermal sensitization and respiratory challenge with low molecular weight chemicals. Toxicol. Appl. Pharmacol. 152:66-76.
7. Arts, J. H. E., de Koning, M. W., Bloksma, N., and Kuper, C. F. 2001. Respiratory irritation by trimellitic anhydride in Brown Norway and Wistar rats. Inhal. Toxicol. 13:719-728.
8. Bernstein, D. I., Roach, D. E., McGrath, K. G., Larsen, R. S., Zeiss, C. R., and Patterson, R. 1983. The relationship of airborne trimellitic anhydride concentrations to trimellitic anhydride-induced symptoms and immune responses. J. Allergy Clin. Immunol. 72:709-713.
9. Blaikie, L., Morrow, T., Wilson, A. P., Hext, P., Hartop, P. J., Rattray, N. J., Woodcock, D., and Botham, P. A. 1995. A two-centre study for the evaluation and validation of an animal model for the assessment of the potential of small molecular weight chemicals to cause respiratory allergy. Toxicology 96:37-50.
10. Botham, P. A., Rattray, N. J., Woodcock, D. R., Walsh, S. T., and Hext, P. M. 1989. The induction of respiratory allergy in guinea-pigs following intradermal injection of trimellitic anhydride; A comparison with the response to 2,4-dinitrochlorobenzene. Toxicol. Lett. 47:25-39.
11. Chan-Yeung, M., and Malo, J.-L. 1995. Occupational asthma. N. Engl. J. Med. 333:107-113.
12. Dearman, R. J., and Kimber, I. 1991. Differential stimulation of immune function by respiratory and contact chemical allergens. Immunology 72:563-570.
13. De Ceaurriz, J. C., Micillino, J. C., Bonnet, P., and Guenier, J. P. 1981. Sensory irritation caused by various industrial airborne chemicals. Toxicol. Lett. 9:137-142.
14. Fabbri, L. M., Danieli, D., Crescioli, S., Bevilacqua, P., Meli, S., Saetta, M., and Mapp, C. E. 1988. Fatal asthma in a subject sensitized to toluene diisoyanate. Am. Rev. Respir. Dis. 137:1494-1498.
15. Germann, P.-G., Haefner, D., Hanauer, G., and Drommer, W. 1998. Incidence and severity of granulomatous pneumonia in Brown Norway (BN) rats: Breeder related variations. J. Exp. Anim. Sci. 39:22-33.
16. Hamelmann, E., Schwarze, J., Takeda, K., Oshiba, A., Irvin, C. G., and Gelfand, E. W. 1997. Noninvasive measurement of airway responsiveness in allergic mice using barometric plethysmography. Am. J. Respir. Crit. Care. Med. 156:766-775.
17. Hilton, J., Dearman, R. J., Basketter, D. A., and Kimber, I. 1995. Identification of chemical respiratory allergens: Dose-response relationships in the mouse IgE test. Toxicol. Methods 5:51-60.
18. Lozewicz, B. D., Assoufi, B. K., Hawkins, R., and Taylor, A. J. 1987. Outcome of asthma induced by isocyanates. Br. J. Dis. Chest 81:14-22.
19. Michielsen, C. P. P. C., Leusink-Muis, A., Vos, J. G., and Bloksma, N. 1999. Hexachlorobenzene-induced eosinophilic and granulomatous lung inflammation is associated with in vivo airways hyperresponsiveness in the Brown Norway rat. Thesis, Utrecht University, Utrecht, The Netherlands. 97-111.
20. O'Neill, R. 1995. Asthma at work. Causes, effects and what to do about them, p. 133. Trades Union Congress/Sheffield Occupational Health Project Co-op Ltd., Sheffield, UK.
21. Paggiaro, P. L., Vagaggini, B., Dente, F. L., Bacci, E., Bancalari, L., Carrara, M., Di-Franco, A., Giannini, D., and Giuntini, C. 1993. Bronchial hyperresponsiveness and toluene diisocyanate. Long-term change in sensitized asthmatic subjects. Chest 103:1123-1128.
22. Pauluhn, J., Eidmann, P., Freyberger, A., Wasinska-Kempka, G., and Vohr, H.-W. 2002. Respiratory hypersensitivity to trimellitic anhydride in Brown Norway rats: A comparison of endpoints. J. Appl. Toxicol. 22:89-97.
23. Piirilä, P. L., Nordman, H., Keskinen, H. M., Luukkonen, R., Salo, S. P., Tuomi, T. O., and Tuppurainen, M. 2000. Long-term follow-up of hexamethylene diisocyanate-, biphenylmethane diisocyanate-, and toluene diisocyanate-induced asthma. Am. J. Respir. Crit. Care Med. 162:516-522.
24. Pisati, G., Baruffini, A., and Zedda, S. 1993. Toluene diisocyanate induced asthma: Outcome according to persistence or cessation of exposure. Br. J. Ind. Med. 50:60-64.
25. Potter, D. W., and Wederbrand, K. S. 1995. Total IgE antibody production in BALB/c mice after dermal exposure to chemicals. Fundam. Appl. Toxicol. 26:127-135.
26. Saetta, M., Maestrelli, P., Di Stefano, A., De Marzo, N., Milani, G. F., Pivirotto, F., Mapp, C. E., and Fabbri, L. M. 1992. Effect of cessation of exposure to toluene diisocyanate (TDI) in bronchial mucosa of subjects with TDI-induced asthma. Am. Rev. Respir. Dis. 145:169-174.
27. Sandler, H. M. 2000. Regulating allergies at the workplace. Occup. Hazards 62:149-151.
28. Schaper, M., and Brost, M. A. 1991. Respiratory effects of trimellitic anhydride aerosols in mice. Arch. Toxicol. 65:671-677.
29. Warbrick, E. V., Dearman, R. J., and Kimber, I. 2002. IgG and IgE antibody responses following exposure of Brown Norway rats to trimellitic anhydride: Comparison of inhalation and topical exposure. Toxicology 172:157-168.
30. Zeiss, C. R., and Patterson, R. 1993. Acid anhydrides. In: Asthma in the workplace, eds. I. L. Bernstein, M. Chan-Yeung, J.-L. Malo, and D.I. Bernstein, pp. 439-457. New York: Marcel Dekker.