Synergistic QTL interactions between Rf-1 and Rf-3 increase renal damage susceptibility in double congenic rats

Kidney International

Volumn 69, Issue 8, 2006, Pages 1369-1376

  Van Dijk, S J ^a   Specht, P A C ^a   Lazar, J ^b   Jacob, H J ^b   Provoost, A P ^a  

^a ERASMUS MEDICAL CENTER   (Netherlands)

^b MEDICAL COLLEGE OF WISCONSIN   (United States)

Author keywords

Congenic rats; L NAME hypertension; Proteinuria; Renal damage susceptibility; Unilateral nephrectomy

Indexed keywords

N(G) NITROARGININE METHYL ESTER;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTOREGULATION; CHRONIC KIDNEY DISEASE; CONGENIC STRAIN; CONTROLLED STUDY; DISEASE PREDISPOSITION; HYPERTENSION; KIDNEY BLOOD FLOW; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEINURIA; QUANTITATIVE TRAIT LOCUS; RAT; SYSTOLIC BLOOD PRESSURE; UNINEPHRECTOMY;

ADMINISTRATION, ORAL; ANIMALS; ANIMALS, CONGENIC; BLOOD PRESSURE; CHROMOSOME MAPPING; CHROMOSOMES, MAMMALIAN; ENZYME INHIBITORS; FOLLOW-UP STUDIES; GENETIC MARKERS; GENETIC PREDISPOSITION TO DISEASE; GENOME; HOMEOSTASIS; HOMOZYGOTE; HYPERTENSION, RENAL; KIDNEY DISEASES; MALE; NEPHRECTOMY; NG-NITROARGININE METHYL ESTER; PROTEINURIA; QUANTITATIVE TRAIT LOCI; RATS; RATS, INBRED ACI; RENAL CIRCULATION; SURVIVAL ANALYSIS; TIME FACTORS;

EID: 33646124725     PISSN: 00852538     EISSN: 15231755     Source Type: Journal    
DOI: 10.1038/sj.ki.5000301     Document Type: Article

References (36)

1. National Kidney Foundation. K/DOQI clinical guidelines for chronic kidney disease: evaluation, classification and stratification. Am J Kidney Dis 2002; 39: S1-S266.
2. Coresh J, Byrd-Holt D, Astor BC et al. Chronic kidney disease awareness, prevalence, and trends among US adults, 1999-2000. J Am Soc Nephrol 2005; 16: 180-188.
3. Menon V, Sarnak MJ. The epidemiology of chronic kidney disease stages 1-4 and cardiovascular disease: a high-risk combination. Am J Kidney Dis 2005; 45: 223-232.
4. USRDS. The United States Renal Data System. Am J Kidney Dis 2003; 42: 1-230.
5. Satko SG, Freedman BI. The importance of family history on the development of renal disease. Curr Opin Nephrol Hypertens 2004; 13: 337-341.
6. Freedman BI. Susceptibility genes for hypertension and renal failure. J Am Soc Nephrol 2003; 14: S192-S194.
7. Chow KM, Wong TYH, Li PKT. Genetics of common progressive renal disease. Kidney Int 2005; 67(Suppl 94): S41-S45.
8. Satko SG, Freedman BI, Moossavi S. Genetic factors in end-stage renal disease. Kidney Int 2005; 67(Suppl 94): S46-S49.
9. Provoost AP, De Keijzer MH. The Fawn-Hooded rat: a model for chronic renal failure. In: Gretz N, Strauch M (eds). Experimental and Genetic Rat Models of Chronic Renal Failure, 1st edn, Basel: Karger, 1993, pp 100-114.
10. Simons JL, Provoost AP, Anderson S et al. Pathogenesis of glomerular injury in the fawn-hooded rat: early glomerular capillary hypertension predicts glomerular sclerosis. J Am Soc Nephrol 1993; 3: 1775-1782.
11. Simons JL, Provoost AP, de Keijzer MH et al. Pathogenesis of glomerular injury in the fawn-hooded rat: effect of unilateral nephrectomy. J Am Soc Nephrol 1993; 4: 1362-1370.
12. Kriz W, Hosser H, Hähnel B et al. Development of vascular pole-associated glomerulosclerosis in the fawn-hooded rat. J Am Soc Nephrol 1998; 9: 381-396.
13. Verseput GH, Braam B, Provoost AP, Koomans HA. Tubuloglomerular feedback and prolonged ACE inhibitor treatment in the hypertensive fawn-hooded rat. Nephrol Dial Transplant 1998; 13: 893-899.
14. Van Dokkum RPE, Alonso-Galicia M, Provoost AP et al. Impaired autoregulation of renal blood flow in the fawn-hooded rat. Am J Physiol 1999; 276: R189-R196.
15. Van Dokkum RPE, Sun C, Provoost AP et al. Altered renal hemodynamics and impaired myogenic responses in the fawn-hooded rat. Am J Physiol 1999; 276: R855-R863.
16. Brown DM, Provoost AP, Daly MJ et al. Renal disease susceptibility and hypertension are under independent genetic control in the fawn-hooded rat. Nat Genet 1996; 12: 44-51.
17. Shiozawa M, Provoost AP, Van Dokkum RPE et al. Evidence of gene-gene interactions in the genetic susceptibility to renal impairment after unilateral nephrectomy. J Am Soc Nephrol 2000; 11: 2068-2078.
18. Provoost AP, Shiozawa M, Van Dokkum RPE, Jacob HJ. Transfer of a single genomic region from the fawn-hooded hypertensive rat onto the ACI background increases susceptibility to renal impairment. Physiol Genomics 2002; 8: 123-129.
19. Van Dijk SJ, Specht PAC, Lazar J et al. Renal damage susceptibility and autoregulation in Rf-1 and Rf-5 congenic rats. Nephron Exp Nephrol 2005; 101: e59-e66.
20. Van Dijk SJ, Specht PAC, Lutz MM et al. Interaction between Rf-1 and Rf-4 QTLs increases susceptibility to renal damage in double congenic rats. Kidney Int 2005; 68: 2462-2472.
21. Van Dokkum RPE, Jacob HJ, Provoost AP. Blood pressure and the susceptibility to renal damage after unilateral nephrectomy and L-NAME-induced hypertension rats. Nephrol Dial Transplant 2000; 15: 1337-1343.
22. Van Dokkum RPE, Jacob HJ, Provoost AP. Genetic differences define severity of renal damage after L-NAME-induced hypertension in rats. J Am Soc Nephrol 1998; 9: 363-371.
23. Zatz R, De Nucci G. Effects of acute nitric oxide inhibition on rat glomerular microcirculation. Am J Physiol 1992; 261: F360-F363.
24. Hayakawa H, Raij L. Nitric oxide synthase activity and renal injury in genetic hypertension. Hypertension 1998; 31: 266-270.
25. Brenner BM. Nephron adaptation to renal injury or ablation. Am J Physiol 1985; 249: F324-F337.
26. De Keijzer MH, Provoost AP, Molenaar JC. Glomerular hyperfiltration in hypertensive fawn-hooded rats. Renal Physiol Biochem 1988; 11: 103-108.
27. International Human Genome Sequencing Consortium. Initial sequencing and analysis of the human genome. Nature 2001; 409: 860-921.
28. Venter JC, Adams MD, Myers EW et al. The sequence of the human genome. Science 2001; 291: 1304-1351.
29. Mouse Genome Sequencing Consortium. Initial sequencing and comparative analysis of the mouse genome. Nature 2002; 420: 520-526.
30. Rat Genome Sequencing Project Consortium. Genome sequence of the Brown Norway rat yields insights into mammalian evolution. Nature 2004; 428: 493-521.
31. Imperatore G, Hanson RL, Petitt DJ et al. Sib-pair linkage analysis for susceptibility genes for microvascular complications among Pima Indians with type 2 diabetes. Diabetes 1998; 47: 821-830.
32. Shike T, Gohda T, Tanimoto M et al. Chromosomal mapping of a quantitative trait locus for the development of albuminuria in diatbetic KK/Ta mice. Nephrol Dial Transplant 2005; 20: 879-885.
33. Nicklas W. Microbiological standardization of laboratory animals. Berl Munch Tierartzl Wochenschr 1999; 112: 201-210.
34. Semple SJG, deWardener HE. Effect of increased renal venous pressure on circulatory 'autoregulation' of isolated dog kidneys. Circ Res 1959; 7: 643-648.
35. Watanabe N, Kamei A, Yamanaka M et al. Urinary protein as measured with a pyrogallol red-molybdate complex, manually and in a Hitachi 726 automated analyzer. Clin Chem 1986; 32: 1551-1554.
36. Slot C. Plasma creatinine determination. A new specific Jaffe reaction method. Scand J Clin Lab Invest 1965; 17: 381-387.