Metabolic response to carbohydrate ingestion during exercise in males and females

American Journal of Physiology - Endocrinology and Metabolism

Volumn 290, Issue 4, 2006, Pages

  Wallis, Gareth A ^a   Dawson, Ruth ^a   Achten, Juul ^a   Webber, Jonathan ^b   Jeukendrup, Asker E ^a  

^a UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^b SELLY OAK HOSPITAL   (United Kingdom)

Author keywords

Glucose ingestion; Sex related differences; Stable isotopes; Substrate utilization

Indexed keywords

CARBOHYDRATE; INSULIN; FATTY ACID; GLUCOSE; GLYCEROL; LACTIC ACID;

ADULT; ARTICLE; CALORIMETRY; CARBOHYDRATE INTAKE; CARBOHYDRATE METABOLISM; CONTROLLED STUDY; ENERGY EXPENDITURE; ENERGY YIELD; FEMALE; GLUCOSE BLOOD LEVEL; GLUCOSE OXIDATION; HUMAN; INSULIN BLOOD LEVEL; LEAN BODY WEIGHT; LIPOLYSIS; MALE; OXIDATION KINETICS; PHYSICAL STRESS; PRIORITY JOURNAL; SEX DIFFERENCE; BLOOD; CARBOHYDRATE DIET; EXERCISE; METABOLISM; PHYSIOLOGY;

ADULT; BLOOD GLUCOSE; CALORIMETRY, INDIRECT; DIETARY CARBOHYDRATES; EXERCISE; FATTY ACIDS, NONESTERIFIED; FEMALE; GLUCOSE; GLYCEROL; HUMANS; INSULIN; LACTIC ACID; MALE; SEX FACTORS;

EID: 33646096013     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.00357.2005     Document Type: Article

References (35)

1. Angus DJ, Hargreaves M, Dancey J, and Febbraio MA. Effect of carbohydrate or carbohydrate plus medium-chain triglyceride ingestion on cycling time trial performance. J Appl Physiol 88: 113-119, 2000.
2. Bailey SP, Zacher CM, and Mittleman KD. Effect of menstrual cycle phase on carbohydrate supplementation during prolonged exercise to fatigue. J Appl Physiol 88: 690-697, 2000.
3. Bosch AN, Dennis SC, and Noakes TD. Influence of carbohydrate ingestion on fuel substrate turnover and oxidation during prolonged exercise. J Appl Physiol 76: 2364-2372, 1994.
4. Campbell PJ, Carlson MG, Hill JO, and Nurjhan N. Regulation of free fatty acid metabolism by insulin in humans: role of lipolysis and reesterification. Am J Physiol Endocrinol Metab 263: E1063-E1069, 1992.
5. Campbell SE, Angus DJ, and Febbraio MA. Glucose kinetics and exercise performance during phases of the menstrual cycle: effect of glucose ingestion. Am J Physiol Endocrinol Metab 281: E817-E825, 2001.
6. Coggan AR and Coyle EF. Metabolism and performance following carbohydrate ingestion late in exercise. Med Sci Sports Exerc 21: 59-65, 1989.
7. Coyle EF. Fluid and fuel intake during exercise. J Sports Sci 22: 39-55, 2004.
8. Coyle EF, Coggan AR, Hemmert MK, and Ivy JL. Muscle glycogen utilization during prolonged strenuous exercise when fed carbohydrate. J Appl Physiol 61: 165-172, 1986.
9. Davis JM, Jackson DA, Broadwell MS, Queary JL, and Lambert CL. Carbohydrate drinks delay fatigue during intermittent, high-intensity cycling in active men and women. Int J Sport Nutr 7: 261-273, 1997.
10. Febbraio MA, Chiu A, Angus DJ, Arkinstall MJ, and Hawley JA. Effects of carbohydrate ingestion before and during exercise on glucose kinetics and performance. J Appl Physiol 89: 2220-2226, 2000.
11. Febbraio MA, Keenan J, Angus DJ, Campbell SE, and Garnham AP. Preexercise carbohydrate ingestion, glucose kinetics, and muscle glycogen use: effect of the glycemic index. J Appl Physiol 89: 1845-1851, 2000.
12. Hagberg JM and Coyle EF. Physiological determinants of endurance performance as studied in competitive racewalkers. Med Sci Sports Exerc 15: 287-289, 1983.
13. Harris JA and Benedict FG. A biometric study of basal metabolism in man. Carnegie Inst Wash Pub 279: 227, 1919.
14. Horowitz JF, Mora-Rodriguez R, Byerley LO, and Coyle EF. Lipolytic suppression following carbohydrate ingestion limits fat oxidation during exercise. Am J Physiol Endocrinol Metab 273: E768-E775, 1997.
15. Jackson AS and Pollock ML. Generalized equations for predicting body density of men. Br J Nutr 40: 497-504, 1978.
16. Jackson AS, Pollock ML, and Ward A. Generalized equations for predicting body density of women. Med Sci Sports Exerc 12: 175-181, 1980.
17. Jentjens R, Underwood K, Achten J, Currell K, Mann CH, and Jeukendrup AE. Exogenous carbohydrate oxidation rates are elevated following combined ingestion of glucose and fructose during exercise in the heat. J Appl Physiol 100: 807-816, 2006.
18. Jeukendrup AE. Carbohydrate intake during exercise and performance. Nutrition 20: 669-677, 2004.
19. Jeukendrup AE and Jentjens R. Oxidation of carbohydrate feedings during prolonged exercise: current thoughts, guidelines and directions for future research. Sports Med 29: 407-424, 2000.
20. Jeukendrup AE, Raben A, Gijsen A, Stegen JH, Brouns F, Saris WH, and Wagenmakers AJ. Glucose kinetics during prolonged exercise in highly trained human subjects: effect of glucose ingestion. J Physiol 515: 579-589, 1999.
21. Jeukendrup AE, Wagenmakers AJ, Stegen JH, Gijsen AP, Brouns F, and Saris WH. Carbohydrate ingestion can completely suppress endogenous glucose production during exercise. Am J Physiol Endocrinol Metab 276: E672-E683, 1999.
22. Jeukendrup AE and Wallis GA. Measurement of substrate oxidation during exercise by means of gas exchange measurements. Int J Sports Med 26 Suppl 1: S28-S37, 2005.
23. M'Kaouar H, Peronnet F, Massicotte D, and Lavoie C. Gender difference in the metabolic response to prolonged exercise with [13C]glucose ingestion. Eur J Appl Physiol 92: 462-469, 2004.
24. McConell G, Fabris S, Proietto J, and Hargreaves M. Effect of carbohydrate ingestion on glucose kinetics during exercise. J Appl Physiol 77: 1537-1541, 1994.
25. Pallikarakis N, Sphiris N, and Lefebvre P. Influence of the bicarbonate pool and on the occurrence of 13CO2 in exhaled air. Eur J Appl Physiol Occup Physiol 63: 179-183, 1991.
26. Pirnay F, Lacroix M, Mosora F, Luyckx A, and Lefebvre P. Effect of glucose ingestion on energy substrate utilization during prolonged muscular exercise. Eur J Appl Physiol Occup Physiol 36: 247-254, 1977.
27. Riddell MC, Partington SL, Stupka N, Armstrong D, Rennie C, and Tarnopolsky MA. Substrate utilization during exercise performed with and without glucose ingestion in female and male endurance trained athletes. Int J Sport Nutr Exerc Metab 13: 407-421, 2003.
28. 13C-labeled glucose for estimating glucose oxidation: some design considerations. J Appl Physiol 63: 1725-1732, 1987.
29. Steele R. Influences of glucose loading and of injected insulin on hepatic glucose output. Ann NY Acad Sci 82: 420-430, 1959.
30. Tarnopolsky MA. Females and males: should nutritional recommendations be gender specific? Scheizerische Zeitschrift fur Sportmedizin and Sporttraumatologie 51: 39-46, 2003.
31. Tarnopolsky MA. Gender Differences in Metabolism: Practical and Nutritional Implications. Boca Raton, FL: CRC, 1999.
32. Tarnopolsky MA. Gender differences in metabolism; nutrition and supplements. J Sci Med Sport 3: 287-298, 2000.
33. Tarnopolsky MA. Gender differences in substrate metabolism during endurance exercise. Can J Appl Physiol 25: 312-327, 2000.
34. Wallis GA, Rowlands DS, Shaw C, Jentjens RL, and Jeukendrup AE. Oxidation of combined ingestion of maltodextrins and fructose during exercise. Med Sci Sports Exerc 37: 426-432, 2005.
35. Wolfe RR and Chinkes DL. Isotopic Tracers in Metabolic Research: Principles and Practice of Kinetic Analysis. Hoboken, NJ: Wiley and Sons, 2005.