Effects of riluzole on N-methyl-D-aspartate-induced tyrosine phosphorylation in the rat hippocampus

Brain Research

Volumn 903, Issue 1-2, 2001, Pages 222-225

  Peyclit, Agnès ^a   Keita, Hawa ^a   Juvin, Philippe ^a   Derkinderen, Pascal ^b   Jardinaud, Fanny ^a   Rouellé, Danielle ^a   Boczkowski, Jorge ^a   Desmonts, Jean Marie ^a   Girault, Jean Antoine ^b   Mantz, Jean ^a  

^a INSERM   (France)

^b IFM   (France)

Author keywords

Hippocampus; Immunoprecipitation; Protein kinase C; Riluzole; Tyrosine phosphorylation

Indexed keywords

2 [1 (3 DIMETHYLAMINOPROPYL) 3 INDOLYL] 3 (3 INDOLYL)MALEIMIDE; DIZOCILPINE; GLUTAMIC ACID; N METHYL DEXTRO ASPARTIC ACID; PHORBOL 13 ACETATE 12 MYRISTATE; PROTEIN KINASE C INHIBITOR; RILUZOLE; TYROSINE;

ANIMAL TISSUE; ARTICLE; BRAIN SLICE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; DRUG POTENCY; HIPPOCAMPUS; IC 50; MALE; NEUROPROTECTION; NEUROTRANSMISSION; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT;

ANIMALS; CARCINOGENS; EXCITATORY AMINO ACID AGONISTS; HIPPOCAMPUS; MALE; N-METHYLASPARTATE; NEUROPROTECTIVE AGENTS; NEUROTOXINS; PHOSPHORYLATION; PRECIPITIN TESTS; PROTEIN KINASE C; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, GLUTAMATE; RILUZOLE; TETRADECANOYLPHORBOL ACETATE; TYROSINE;

EID: 0035827078     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(01)02429-5     Document Type: Article

References (18)

1. Cloning of focal adhesion kinase, pp125FAK, from rat brain reveals multiple transcripts with different patterns of expression
2. Tyrosine phosphorylation of microtubule-associated protein kinase after transient ischemia in the gerbil brain
3. Riluzole inhibits release of glutamate in the caudate nucleus of the cat in vitro
4. Inhibition by riluzole of electrophysiological responses mediated by rat kainate and NMDA receptors expressed in Xenopus oocytes
5. Differential regulation of FAK and PYK2/CAKβ, two related tyrosine kinases, in rat hippocampal slices: Effects of LPA, carbachol, depolarization and hyperosmolarity
6. Protective effect of riluzole on excitatory amino acid-mediated neurotoxicity in motoneuron-enriched cultures
7. FAK and PYK2/CAKβ in the nervous system: A link between neuronal activity, plasticity and survival?
8. Block of the rat brain IIA sodium channel A subunit by the neuroprotective drug riluzole
9. Changes in tyrosine phosphorylation in neocortex following transient cerebral ischemia
10. Antagonism by riluzole of entry of calcium evoked by NMDA and veratridine in rat cultured granule cells: Evidence for a dual mechanism of action
11. Anesthetic concentrations of riluzole inhibit neuronal nitric oxide synthase activity, but not expression, in the rat hippocampus
12. Inhibition of tyrosine phosphorylation prevents delayed neuronal death following cerebral ischemia
13. Dose-ranging study of riluzole in amyotrophic lateral sclerosis
14. Riluzole, a novel antiglutamate, prevents memory loss and hippocampal neuronal damage in ischemic gerbils
15. Tyrosine phosphorylation of NMDA receptor in rat striatum: Effects of 6-OH-dopamine lesions
16. Delayed neuronal death in ischemic hippocampus involves stimulation of protein tyrosine phosphorylation
17. Antiphosphotyrosine antibodies for studying protein phosphorylation in neural cells: Applications to brain slices and cultured cells
18. Differential regulation of proline-rich tyrosine kinase 2/cell adhesion kinase β (PYK 2/CAKβ) and pp125FAK by glutamate and depolarization in the rat hippocampus