-
1
-
-
0028807727
-
T lymphocyte-directed gene therapy for ADA-SCID: initial trial results after 4 years
-
Blaese R.M., Culver K.W., Miller A.D., Carter C.S., Fleisher T., Clerici M., Shearer G., Chang L., Chiang Y., Tolstoshev P., Greenblatt J.J., Rosenberg S.A., Klein H., Berger M., Mullen C.A., Ramsey W.J., Muul L., Morgan R.A., and Anderson W.F. T lymphocyte-directed gene therapy for ADA-SCID: initial trial results after 4 years. Science 270 (1995) 475-480
-
(1995)
Science
, vol.270
, pp. 475-480
-
-
Blaese, R.M.1
Culver, K.W.2
Miller, A.D.3
Carter, C.S.4
Fleisher, T.5
Clerici, M.6
Shearer, G.7
Chang, L.8
Chiang, Y.9
Tolstoshev, P.10
Greenblatt, J.J.11
Rosenberg, S.A.12
Klein, H.13
Berger, M.14
Mullen, C.A.15
Ramsey, W.J.16
Muul, L.17
Morgan, R.A.18
Anderson, W.F.19
-
2
-
-
0028385758
-
Versatile retroviral vectors for potential use in gene therapy
-
Hawley R.G., Lieu F.H., Fong A.Z., and Hawley T.S. Versatile retroviral vectors for potential use in gene therapy. Gene Ther. 1 (1994) 136-138
-
(1994)
Gene Ther.
, vol.1
, pp. 136-138
-
-
Hawley, R.G.1
Lieu, F.H.2
Fong, A.Z.3
Hawley, T.S.4
-
3
-
-
0028883813
-
Novel retroviral vectors for efficient expression of the multidrug resistance (mdr-1) gene in early hematopoietic cells
-
Baum C., Hegewisch-Becker S., Eckert H.G., Stocking C., and Ostertag W. Novel retroviral vectors for efficient expression of the multidrug resistance (mdr-1) gene in early hematopoietic cells. J. Virol. 69 (1995) 7541-7547
-
(1995)
J. Virol.
, vol.69
, pp. 7541-7547
-
-
Baum, C.1
Hegewisch-Becker, S.2
Eckert, H.G.3
Stocking, C.4
Ostertag, W.5
-
4
-
-
0030862341
-
Increased probability of expression from modified retroviral vectors in embryonal stem cells and embryonal carcinoma cells
-
Robbins P.B., Yu X.J., Skelton D.M., Pepper K.A., Wasserman R.M., Zhu L., and Kohn D.B. Increased probability of expression from modified retroviral vectors in embryonal stem cells and embryonal carcinoma cells. J. Virol. 71 (1997) 9466-9474
-
(1997)
J. Virol.
, vol.71
, pp. 9466-9474
-
-
Robbins, P.B.1
Yu, X.J.2
Skelton, D.M.3
Pepper, K.A.4
Wasserman, R.M.5
Zhu, L.6
Kohn, D.B.7
-
5
-
-
0031739805
-
FMEV vectors: both retroviral long terminal repeat and leader are important for high expression in transduced hematopoietic cells
-
Hildinger M., Eckert H.G., Schilz A.J., John J., Ostertag W., and Baum C. FMEV vectors: both retroviral long terminal repeat and leader are important for high expression in transduced hematopoietic cells. Gene Ther. 5 (1998) 1575-1579
-
(1998)
Gene Ther.
, vol.5
, pp. 1575-1579
-
-
Hildinger, M.1
Eckert, H.G.2
Schilz, A.J.3
John, J.4
Ostertag, W.5
Baum, C.6
-
6
-
-
0028815676
-
Multiple modifications in cis elements of the long terminal repeat of retroviral vectors lead to increased expression and decreased DNA methylation in embryonic carcinoma cells
-
Challita P.M., Skelton D., el-Khoueiry A., Yu X.J., Weinberg K., and Kohn D.B. Multiple modifications in cis elements of the long terminal repeat of retroviral vectors lead to increased expression and decreased DNA methylation in embryonic carcinoma cells. J. Virol. 69 (1995) 748-755
-
(1995)
J. Virol.
, vol.69
, pp. 748-755
-
-
Challita, P.M.1
Skelton, D.2
el-Khoueiry, A.3
Yu, X.J.4
Weinberg, K.5
Kohn, D.B.6
-
7
-
-
0029036085
-
Transactivation of the Moloney murine leukemia virus and T-cell receptor beta-chain enhancers by cbf and ets requires intact binding sites for both proteins
-
Sun W., Graves B.J., and Speck N.A. Transactivation of the Moloney murine leukemia virus and T-cell receptor beta-chain enhancers by cbf and ets requires intact binding sites for both proteins. J. Virol. 69 (1995) 4941-4949
-
(1995)
J. Virol.
, vol.69
, pp. 4941-4949
-
-
Sun, W.1
Graves, B.J.2
Speck, N.A.3
-
8
-
-
0031657705
-
In vivo footprinting of the enhancer sequences in the upstream long terminal repeat of Moloney murine leukemia virus: differential binding of nuclear factors in different cell types
-
Granger S.W., and Fan H. In vivo footprinting of the enhancer sequences in the upstream long terminal repeat of Moloney murine leukemia virus: differential binding of nuclear factors in different cell types. J. Virol. 72 (1998) 8961-8970
-
(1998)
J. Virol.
, vol.72
, pp. 8961-8970
-
-
Granger, S.W.1
Fan, H.2
-
9
-
-
0024404485
-
Mechanism of suppression of the long terminal repeat of Moloney leukemia virus in mouse embryonal carcinoma cells
-
Tsukiyama T., Niwa O., and Yokoro K. Mechanism of suppression of the long terminal repeat of Moloney leukemia virus in mouse embryonal carcinoma cells. Mol. Cell. Biol. 9 (1989) 4670-4676
-
(1989)
Mol. Cell. Biol.
, vol.9
, pp. 4670-4676
-
-
Tsukiyama, T.1
Niwa, O.2
Yokoro, K.3
-
10
-
-
0025952211
-
A single point mutation activates the Moloney murine leukemia virus long terminal repeat in embryonal stem cells
-
Grez M., Zornig M., Nowock J., and Ziegler M. A single point mutation activates the Moloney murine leukemia virus long terminal repeat in embryonal stem cells. J. Virol. 65 (1991) 4691-4698
-
(1991)
J. Virol.
, vol.65
, pp. 4691-4698
-
-
Grez, M.1
Zornig, M.2
Nowock, J.3
Ziegler, M.4
-
11
-
-
0026134161
-
Retroviral vectors related to the myeloproliferative sarcoma virus allow efficient expression in hematopoietic stem and precursor cell lines, but retroviral infection is reduced in more primitive cells
-
Beck-Engeser G., Stocking C., Just U., Albritton L., Dexter M., Spooncer E., and Ostertag W. Retroviral vectors related to the myeloproliferative sarcoma virus allow efficient expression in hematopoietic stem and precursor cell lines, but retroviral infection is reduced in more primitive cells. Hum. Gene Ther. 2 (1991) 61-70
-
(1991)
Hum. Gene Ther.
, vol.2
, pp. 61-70
-
-
Beck-Engeser, G.1
Stocking, C.2
Just, U.3
Albritton, L.4
Dexter, M.5
Spooncer, E.6
Ostertag, W.7
-
12
-
-
0029909913
-
High-dose multidrug resistance in primary human hematopoietic progenitor cells transduced with optimized retroviral vectors
-
Eckert H.G., Stockschlader M., Just U., Hegewisch-Becker S., Grez M., Uhde A., Zander A., Ostertag W., and Baum C. High-dose multidrug resistance in primary human hematopoietic progenitor cells transduced with optimized retroviral vectors. Blood 88 (1996) 3407-3415
-
(1996)
Blood
, vol.88
, pp. 3407-3415
-
-
Eckert, H.G.1
Stockschlader, M.2
Just, U.3
Hegewisch-Becker, S.4
Grez, M.5
Uhde, A.6
Zander, A.7
Ostertag, W.8
Baum, C.9
-
13
-
-
0035173080
-
Simplified retroviral vector gcsap with murine stem cell virus long terminal repeat allows high and continued expression of enhanced green fluorescent protein by human hematopoietic progenitors engrafted in nonobese diabetic/severe combined immunodeficient mice
-
Kaneko S., Onodera M., Fujiki Y., Nagasawa T., and Nakauchi H. Simplified retroviral vector gcsap with murine stem cell virus long terminal repeat allows high and continued expression of enhanced green fluorescent protein by human hematopoietic progenitors engrafted in nonobese diabetic/severe combined immunodeficient mice. Hum. Gene Ther. 12 (2001) 35-44
-
(2001)
Hum. Gene Ther.
, vol.12
, pp. 35-44
-
-
Kaneko, S.1
Onodera, M.2
Fujiki, Y.3
Nagasawa, T.4
Nakauchi, H.5
-
14
-
-
0043269706
-
Retroviral vectors for high-level transgene expression in T lymphocytes
-
Engels B., Cam H., Schuler T., Indraccolo S., Gladow M., Baum C., Blankenstein T., and Uckert W. Retroviral vectors for high-level transgene expression in T lymphocytes. Hum. Gene Ther. 14 (2003) 1155-1168
-
(2003)
Hum. Gene Ther.
, vol.14
, pp. 1155-1168
-
-
Engels, B.1
Cam, H.2
Schuler, T.3
Indraccolo, S.4
Gladow, M.5
Baum, C.6
Blankenstein, T.7
Uckert, W.8
-
15
-
-
85047699090
-
High expression of transgenes mediated by hybrid retroviral vectors in hepatocytes: comparison of promoters from murine retroviruses in vitro and in vivo
-
Ohnishi N., Itoh K., Itoh Y., Baum C., Higashitsuji H., Yamaguchi K., Tsuji T., Okanoue T., and Fujita J. High expression of transgenes mediated by hybrid retroviral vectors in hepatocytes: comparison of promoters from murine retroviruses in vitro and in vivo. Gene Ther. 9 (2002) 303-306
-
(2002)
Gene Ther.
, vol.9
, pp. 303-306
-
-
Ohnishi, N.1
Itoh, K.2
Itoh, Y.3
Baum, C.4
Higashitsuji, H.5
Yamaguchi, K.6
Tsuji, T.7
Okanoue, T.8
Fujita, J.9
-
16
-
-
0037927848
-
Construction of a high efficiency retroviral vector for gene therapy of Hunter's syndrome
-
Hong Y., Yu S.S., Kim J.M., Lee K., Na Y.S., Whitley C.B., Sugimoto Y., and Kim S. Construction of a high efficiency retroviral vector for gene therapy of Hunter's syndrome. J. Gene Med. 5 (2003) 18-29
-
(2003)
J. Gene Med.
, vol.5
, pp. 18-29
-
-
Hong, Y.1
Yu, S.S.2
Kim, J.M.3
Lee, K.4
Na, Y.S.5
Whitley, C.B.6
Sugimoto, Y.7
Kim, S.8
-
18
-
-
0037728737
-
Construction of a retroviral vector production system with the minimum possibility of a homologous recombination
-
Yu S.S., Han E., Hong Y., Lee J.T., and Kim S. Construction of a retroviral vector production system with the minimum possibility of a homologous recombination. Gene Ther. 10 (2003) 706-711
-
(2003)
Gene Ther.
, vol.10
, pp. 706-711
-
-
Yu, S.S.1
Han, E.2
Hong, Y.3
Lee, J.T.4
Kim, S.5
-
19
-
-
0032784630
-
Rapid titer determination using quantitative real-time PCR
-
Sanburn N., and Cornetta K. Rapid titer determination using quantitative real-time PCR. Gene Ther. 6 (1999) 1340-1345
-
(1999)
Gene Ther.
, vol.6
, pp. 1340-1345
-
-
Sanburn, N.1
Cornetta, K.2
-
20
-
-
0037431266
-
Real-time quantitative reverse transcriptase-polymerase chain reaction as a method for determining lentiviral vector titers and measuring transgene expression
-
Lizee G., Aerts J.L., Gonzales M.I., Chinnasamy N., Morgan R.A., and Topalian S.L. Real-time quantitative reverse transcriptase-polymerase chain reaction as a method for determining lentiviral vector titers and measuring transgene expression. Hum. Gene Ther. 14 (2003) 497-507
-
(2003)
Hum. Gene Ther.
, vol.14
, pp. 497-507
-
-
Lizee, G.1
Aerts, J.L.2
Gonzales, M.I.3
Chinnasamy, N.4
Morgan, R.A.5
Topalian, S.L.6
-
21
-
-
0028918657
-
A transient three-plasmid expression system for the production of high titer retroviral vectors
-
Soneoka Y., Cannon P.M., Ramsdale E.E., Griffiths J.C., Romano G., Kingsman S.M., and Kingsman A.J. A transient three-plasmid expression system for the production of high titer retroviral vectors. Nucleic Acids Res. 23 (1995) 628-633
-
(1995)
Nucleic Acids Res.
, vol.23
, pp. 628-633
-
-
Soneoka, Y.1
Cannon, P.M.2
Ramsdale, E.E.3
Griffiths, J.C.4
Romano, G.5
Kingsman, S.M.6
Kingsman, A.J.7
-
22
-
-
0031803564
-
Generation of a conditionally neo(r)-containing retroviral producer cell line: effects of neo(r) on retroviral titer and transgene expression
-
Wildner O., Candotti F., Krecko E.G., Xanthopoulos K.G., Ramsey W.J., and Blaese R.M. Generation of a conditionally neo(r)-containing retroviral producer cell line: effects of neo(r) on retroviral titer and transgene expression. Gene Ther. 5 (1998) 684-691
-
(1998)
Gene Ther.
, vol.5
, pp. 684-691
-
-
Wildner, O.1
Candotti, F.2
Krecko, E.G.3
Xanthopoulos, K.G.4
Ramsey, W.J.5
Blaese, R.M.6
-
23
-
-
0031788862
-
The selectable marker neo gene down-regulates gene expression from retroviral vectors containing an internal ribosome entry site
-
Byun J., Kim J.M., Robbins P.D., and Kim S. The selectable marker neo gene down-regulates gene expression from retroviral vectors containing an internal ribosome entry site. Gene Ther. 5 (1998) 1441-1444
-
(1998)
Gene Ther.
, vol.5
, pp. 1441-1444
-
-
Byun, J.1
Kim, J.M.2
Robbins, P.D.3
Kim, S.4
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