The effect of mGlu5 receptor positive allosteric modulators on signaling molecules in brain slices

European Journal of Pharmacology

Volumn 536, Issue 3, 2006, Pages 262-268

  Liu, Feng ^a   Zhang, Guoming ^a   Hornby, Geoffrey ^a   Vasylyev, Dmytro ^a   Bowlby, Mark ^a   Park, Kaapjoo ^a,b   Gilbert, Adam ^a,b   Marquis, Karen ^a   Andree, Terrance H ^a  

^a Neuroscience Discovery Research   (United States)

^b WYETH RESEARCH   (United States)

Author keywords

Cyclic AMP responsive element binding protein; Extracellular signal regulated protein kinase; Metabotropic glutamate receptor subtype 5; N methyl d aspartate receptor; N 4 chloro 2 (1,3 dioxo 1,3 dihydro 2H isoindol 2yl) methyl phenyl 2 hydrobenzamide

Indexed keywords

3,5 DIHYDROXYPHENYLGLYCINE; BENZAMIDE DERIVATIVE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; GLUTAMIC ACID; METABOTROPIC RECEPTOR 5; METABOTROPIC RECEPTOR AGONIST; MITOGEN ACTIVATED PROTEIN KINASE; N [4 CHLORO 2 [(1,3 DIOXO 1,3 DIHYDRO 2H ISOINDOL 2 YL) METHYL]PHENYL] 2 HYDROBENZAMIDE; N METHYL DEXTRO ASPARTIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 1; UNCLASSIFIED DRUG;

ALLOSTERISM; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; BRAIN SLICE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DRUG SELECTIVITY; EMBRYO; ENZYME ACTIVITY; HIPPOCAMPUS; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION;

ACTION POTENTIALS; ANIMALS; BENZAMIDES; BRAIN; CELLS, CULTURED; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SYNERGISM; EXCITATORY AMINO ACID ANTAGONISTS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GLYCINE; HIPPOCAMPUS; MALE; MICE; MICE, INBRED C57BL; PHOSPHORYLATION; PHTHALIMIDES; PYRAMIDAL CELLS; RABBITS; RECEPTORS, METABOTROPIC GLUTAMATE; RECEPTORS, N-METHYL-D-ASPARTATE; RESORCINOLS; SIGNAL TRANSDUCTION;

EID: 33646069922     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2006.02.003     Document Type: Article

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