Cytokine responses in gnotobiotic pigs after infection with virulent or attenuated human rotavirus

Journal of Virology

Volumn 80, Issue 1, 2006, Pages 372-382

  Azevedo, M S P ^a   Yuan, L ^a   Pouly, S ^a   Gonzales, A M ^a   Jeong, K I ^a   Nguyen, T V ^a   Saif, L J ^a  

^a OHIO STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; IMMUNOGLOBULIN A; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 4; INTERLEUKIN 6; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DIARRHEA; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME LINKED IMMUNOSPOT ASSAY; GNOTOBIOTICS; ILEUM; IMMUNE RESPONSE; MONONUCLEAR CELL; NEWBORN; NONHUMAN; PRIORITY JOURNAL; ROTAVIRUS; SPLEEN; SWINE; TH1 CELL; TH2 CELL; TH3 CELL; VIREMIA; VIRUS INFECTION; VIRUS STRAIN; VIRUS VIRULENCE;

ANIMALS; ANTIBODIES, VIRAL; CYTOKINES; DISEASE MODELS, ANIMAL; GERM-FREE LIFE; HUMANS; INTESTINES; ROTAVIRUS; ROTAVIRUS INFECTIONS; SWINE; VACCINES, ATTENUATED; VIRULENCE;

ANIMALIA; HUMAN ROTAVIRUS A; ROTAVIRUS; SUS SCROFA;

EID: 33646049712     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.80.1.372-382.2006     Document Type: Article

References (52)

1. Angel, J., M. A. Franco, H. B. Greenberg, and D. Bass. 1999. Lack of a role for type I and type II interferons in the resolution of rotavirus-induced diarrhea and infection in mice. J. Interferon Cytokine Res. 19:655-659.
2. Asseman, C., S. Mauze, M. W. Leach, R. L. Coffman, and F. Powrie. 1999. An essential role for interleukin 10 in the function of regulatory T cells that inhibit intestinal inflammation. J. Exp. Med. 190:995-1004.
3. Azevedo, M. S., L. Yuan, C. Iosef, K. O. Chang, Y. Kim, T. V. Nguyen, and L. J. Saif. 2004. Magnitude of serum and intestinal antibody responses induced by sequential replicating and nonreplicating rotavirus vaccines in gnotobiotic pigs and correlation with protection. Clin. Diagn. Lab Immunol. 11:12-20.
4. Azevedo, M. S., L. Yuan, K.. Jeong, A. Gonzalez, T. V. Nguyen, P. S., M. Gochnauer, W. Zhang, A. Azevedo, and L. J. Saif. 2005. Viremia and nasal and rectal shedding of rotavirus in gnotobiotic pigs inoculated with Wa human rotavirus. J. Virol. 79:5428-5436.
5. Azim, T., S. M. Ahmad, E. K. Sefat, M. S. Sarker, L. E. Unicomb, S. De, J. D. Hamadani, M. A. Salam, M. A. Wahed, and M. J. Albert. 1999. Immune response of children who develop persistent diarrhea following rotavirus infection. Clin. Diagn. Lab. Immunol. 6:690-695.
6. Azim, T., M. H. Zaki, G. Fodder, N. Sultana, M. A. Salam, S. M. Rahman, E. K. Sefat, and D. A. Sack. 2003. Rotavirus-specific subclass antibody and cytokine responses in Bangladeshi children with rotavirus diarrhoea. J. Med. Virol. 69:286-295.
7. Bass, D. M. 1997. Interferon gamma and interleukin 1, but not interferon alfa, inhibit rotavirus entry into human intestinal cell lines. Gastroenterology 113:81-89.
8. Billiau, A. 1996. Interferon-gamma: biology and role in pathogenesis. Adv. Immunol. 62:61-130.
9. Bot, A., K. A. Smith, and M. von Herrath. 2004. Molecular and cellular control of T1/T2 immunity at the interface between antimicrobial defense and immune pathology. DNA Cell Biol. 23:341-350.
10. Brown, K. A., J. A. Kriss, C. A. Moser, W. J. Wenner, and P. A. Offit. 2000. Circulating rotavirus-specific antibody-secreting cells (ASCs) predict the presence of rotavirus-specific ASCs in the human small intestinal lamina propria. J. Infect. Dis. 182:1039-1043.
11. Brown, W. C., A. C. Rice-Ficht, and D. M. Estes. 1998. Bovine type 1 and type 2 responses. Vet. Immunol. Immunopathol. 63:45-55.
12. Chan, S. H., B. Perussia, J. W. Gupta, M. Kobayashi, M. Pospisil, H. A. Young, S. F. Wolf, D. Young, S. C. Clark, and G. Trinchieri. 1991. Induction of interferon gamma production by natural killer cell stimulatory factor: characterization of the responder cells and synergy with other inducers. J. Exp. Med. 173:869-879.
13. Coulson, B. S., K. Grimwood, I. L. Hudson, G. L. Barnes, and R. F. Bishop. 1992. Role of coproantibody in clinical protection of children during reinfection with rotavirus. J. Clin. Microbiol. 30:1678-1684.
14. Dawson, H. D., E. Beshah, S. Nishi, G. Solano-Aguilar, M. Morimoto, A. Zhao, K. B. Madden, T. K. Ledbetter, J. P. Dubey, T. Shea-Donohue, J. K. Lunney, and J. F. Urban, Jr. 2005. Localized multigene expression patterns support an evolving Th1/Th2-like paradigm in response to infections with Toxoplasma gondii and Ascaris suum. Infect. Immun. 73:1116-1128.
15. Dhiman, N., I. G. Ovsyannikova, R. C. Howe, J. E. Ryan, R. M. Jacobson, and G. A. Poland. 2004. Interleukin-4 induced by measles virus and measles-derived peptides as measured by IL-4 receptor-blocking ELISA. J. Immunol. Methods 287:217-225.
16. Diaz, I., and E. Mateu. 2005. Use of ELISPOT and ELISA to evaluate IFN-gamma, IL-10 and IL-4 responses in conventional pigs. Vet. Immunol. Immunopathol. 106:107-112.
17. Ekerfelt, C., J. Ernerudh, and M. C. Jenmalm. 2002. Detection of spontaneous and antigen-induced human interleukin-4 responses in vitro: comparison of ELISPOT, a novel ELISA and real-time RT-PCR. J. Immunol. Methods 260:55-67.
18. Fossum, C., E. Wattrang, L. Fuxler, K. T. Jensen, and P. Wallgren. 1998. Evaluation of various cytokines (IL-6, IFN-alpha, IFN-gamma, TNF-alpha) as markers for acute bacterial infection in swine-a possible role for serum interleukin-6. Vet. Immunol. Immunopathol. 64:161-172.
19. Fromantin, C., L. Piroth, I. Petitpas, P. Pothier, and E. Kohli. 1998. Oral delivery of homologous and heterologous strains of rotavirus to BALB/c mice induces the same profile of cytokine production by spleen cells. Virology 244:252-260.
20. Hayden, F. G., R. Fritz, M. C. Lobo, W. Alvord, W. Strober, and S. E. Straus. 1998. Local and systemic cytokine responses during experimental human influenza A virus infection. Relation to symptom formation and host defense. J. Clin. Investig. 101:643-649.
21. Herrero, C., X. Hu, W. P. Li, S. Samuels, M. N. Sharif, S. Kotenko, and L. B. Ivashkiv. 2003. Reprogramming of IL-10 activity and signaling by IFN-gamma. J. Immunol. 171:5034-5041.
22. Hughes, P. A., and L. A. Babiuk. 1995. Potentiation of the immune response by cytokines, p. 183-202. In M. J. Myers and M. P. Murtaugh (ed.), Cytokines in animal health and disease. Marcel Dekker, Inc., New York, N.Y.
23. Jiang, B., L. Snipes-Magaldi, P. Dennehy, H. Keyserling, R. C. Holman, J. Bresee, J. Gentsch, and R. I. Glass. 2003. Cytokines as mediators for or effectors against rotavirus disease in children. Clin. Diagn. Lab. Immunol. 10:995-1001.
24. Lamm, M. E., and J. M. Phillips-Quagliata. 2002. Origin and homing of intestinal IgA antibody-secreting cells. J. Exp. Med. 195:F5-F8.
25. Meyer, R. C., E. H. Bohl, and E. M. Kohler. 1964. Procurement and maintenance of germ-free swine for microbiological investigations. Appl. Microbiol. 12:295-300.
26. Morrison, D. F., D. L. Foss, and M. P. Murtaugh. 2000. Interleukin-10 gene therapy-mediated amelioration of bacterial pneumonia. Infect. Immun. 68: 4752-4758.
27. Murphy, K. M. 1998. T lymphocyte differentiation in the periphery. Curr. Opin. Immunol. 10:226-232.
28. Nakamura, K., A. Kitani, and W. Strober. 2001. Cell contact-dependent immunosuppression by CD4+CD25+ regulatory T cells is mediated by cell surface-bound transforming growth factor β. J. Exp. Med. 194:629-644.
29. Ohshima, Y., and G. Delespesse. 1997. T cell-derived IL-4 and dendritic cell-derived IL-12 regulate the lymphokine-producing phenotype of alloantigen-primed naive human CD4 T cells. J. Immunol. 158:629-636.
30. Paludan, S. R. 1998. Interleukin-4 and interferon-gamma: the quintessence of a mutual antagonistic relationship. Scand. J. Immunol. 48:459-468.
31. Raymond, C. R., and B. N. Wilkie. 2004. Th-1/Th-2 type cytokine profiles of pig T-cells cultured with antigen-treated monocyte-derived dendritic cells. Vaccine 22:1016-1023.
32. Romani, L., A. Mencacci, E. Cenci, R. Spaccapelo, C. Toniatti, P. Puccetti, F. Bistoni, and V. Poli. 1996. Impaired neutrophil response and CD4+ T helper cell 1 development in interleukin 6-deficient mice infected with Candida albicans. J. Exp. Med. 183:1345-1355.
33. Roussel, F., E. Garcia, T. Defrance, C. Peronne, N. Vezzio, D. H. Hsu, R. Kastelein, K. W. Moore, and J. Banchereau. 1992. Interleukin 10 is a potent growth and differentiation factor for activated human B lymphocytes. Proc. Natl. Acad. Sci. USA 89:1890-1893.
34. Saif, L., L. Yuan, L. Ward, and T. To. 1997. Comparative studies of the pathogenesis, antibody immune responses, and homologous protection to porcine and human rotaviruses in gnotobiotic piglets. Adv. Exp. Med. Biol. 412:397-403.
35. Saif, L. J., L. A. Ward, L. Yuan, B. I. Rosen, and T. L. To. 1996. The gnotobiotic piglet as a model for studies of disease pathogenesis and immunity to human rotaviruses. Arch. Virol. Suppl. 12:153-161.
36. Seder, R. A., and W. E. Paul. 1994. Acquisition of lymphokine-producing phenotype by CD4+ T cells. Annu. Rev. Immunol. 12:635-673.
37. Suvas, S., A. K. Azkur, B. S. Kim, U. Kumaraguru, and B. T. Rouse. 2004. CD4+CD25+ regulatory T cells control the severity of viral immunoinflammatory lesions. J. Immunol. 172:4123-4132.
38. Svensson, H., B. Cederblad, M. Lindahl, and G. Alm. 1996. Stimulation of natural interferon-alpha/beta-producing cells by Staphylococcus aureus. J. Interferon Cytokine Res. 16:7-16.
39. To, T. L., L. A. Ward, L. Yuan, and L. J. Saif. 1998. Serum and intestinal isotype antibody responses and correlates of protective immunity to human rotavirus in a gnotobiotic pig model of disease. J. Gen. Virol. 79:2661-2672.
40. VanCott, J. L., T. A. Brim, R. A. Simkins, and L. J. Saif. 1993. Isotype-specific antibody-secreting cells to transmissible gastroenteritis virus and porcine respiratory coronavirus in gut- and bronchus-associated lymphoid tissues of suckling pigs. J. Immunol. 150:3990-4000.
41. Vancott, J. L., M. M. McNeal, A. H. Choi, and R. L. Ward. 2003. The role of interferons in rotavirus infections and protection. J. Interferon Cytokine Res. 23:163-170.
42. van Ginkel, F., H. Nguyen, and J. McGhee. 2000. Vaccines for mucosal immunity to combat emerging infectious diseases. Emerg. Infect. Dis. 6:123-132.
43. Vieira, P. L., J. R. Christensen, S. Minaee, E. J. O'Neill, F. J. Barrat, A. Boonstra, T. Barthlott, B. Stockinger, D. C. Wraith, and A. O'Garra. 2004. IL-10-secreting regulatory T cells do not express Foxp3 but have comparable regulatory function to naturally occurring CD4+CD25+ regulatory T cells. J. Immunol. 172:5986-5993.
44. Wahl, S. M., and W. Chen. 2003. TGF-beta: how tolerant can it be? Immunol. Res. 28:167-179.
45. Ward, L. A., B. I. Rosen, L. Yuan, and L. J. Saif. 1996. Pathogenesis of an attenuated and a virulent strain of group A human rotavirus in neonatal gnotobiotic pigs. J. Gen. Virol. 77:1431-1441.
46. Ward, L. A., L. Yuan, B. I. Rosen, T. L. To, and L. J. Saif. 1996. Development of mucosal and systemic lymphoproliferative responses and protective immunity to human group A rotaviruses in a gnotobiotic pig model. Clin. Diagn. Lab. Immunol. 3:342-350.
47. Wattrang, E., P. Wallgren, and C. Fossum. 1998. Actinobacillus pleuropneumonia serotype 2-effects on the interferon-alpha production of porcine leukocytes in vivo and in vitro. Comp. Immunol. Microbiol. Infect. Dis. 21:135-154.
48. Yuan, L., A. Geyer, D. C. Hodgins, Z. Fan, Y. Qian, K. O. Chang, S. E. Crawford, V. Parreno, L. A. Ward, M. K. Estes, M. E. Conner, and L. J. Saif. 2000. Intranasal administration of 2/6-rotavirus-like particles with mutant Escherichia coli heat-labile toxin (LT-R192G) induces antibody-secreting cell responses but not protective immunity in gnotobiotic pigs. J. Virol. 74:8843-8853.
49. Yuan, L., C. Iosef, M. S. Azevedo, Y. Kim, Y. Qian, A. Geyer, T. V. Nguyen, K. O. Chang, and L. J. Saif. 2001. Protective immunity and antibody-secreting cell responses elicited by combined oral attenuated Wa human rotavirus and intranasal Wa 2/6-VLPs with mutant Escherichia coli heat-labile toxin in gnotobiotic pigs. J. Virol. 75:9229-9238.
50. Yuan, L., S. Y. Kang, L. A. Ward, T. L. To, and L. J. Saif. 1998. Antibody-secreting cell responses and protective immunity assessed in gnotobiotic pigs inoculated orally or intramuscularly with inactivated human rotavirus. J. Virol. 72:330-338.
51. Yuan, L., L. A. Ward, B. I. Rosen, T. L. To, and L. J. Saif. 1996. Systematic and intestinal antibody-secreting cell responses and correlates of protective immunity to human rotavirus in a gnotobiotic pig model of disease. J. Virol. 70:3075-3083.
52. Zinkernagel, R. M. 1996. Immunology taught by viruses. Science 271:173-178.