Interleukin-10 gene therapy-mediated amelioration of bacterial pneumonia

Infection and Immunity

Volumn 68, Issue 8, 2000, Pages 4752-4758

  Morrison, Daniel F ^a   Foss, Dennis L ^a   Murtaugh, Michael P ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA GALACTOSIDASE; INTERLEUKIN 1; INTERLEUKIN 10; MYELOPEROXIDASE; RNA; TUMOR NECROSIS FACTOR; ZINC;

ACTINOBACILLUS PLEUROPNEUMONIAE; ADENOVIRUS 5; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL PNEUMONIA; BODY WEIGHT; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME ACTIVITY; GENE THERAPY; LUNG ALVEOLUS MACROPHAGE; LUNG LAVAGE; LUNG WEIGHT; MACROPHAGE ACTIVATION; NONHUMAN; PRIORITY JOURNAL; SWINE; TRACHEA MUCOSA; ZINC BLOOD LEVEL;

ACTINOBACILLUS INFECTIONS; ACTINOBACILLUS PLEUROPNEUMONIAE; ADENOVIRIDAE; ANIMALS; CHEMOTAXIS, LEUKOCYTE; CYTOKINES; GENE THERAPY; GENETIC VECTORS; HUMANS; INTERLEUKIN-10; LUNG; MALE; NEUTROPHILS; PLEUROPNEUMONIA; PNEUMONIA, BACTERIAL; SWINE; ZINC;

EID: 0033914766     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.68.8.4752-4758.2000     Document Type: Article

References (42)

1. Aarden, L. A., E. R. De Groot, O. L. Schaap, and P. M. Lansdorp. 1987. Production of hybridoma growth factor by human monocytes. Eur. J. Immunol. 17:1411-1416.
2. Armstrong, L., N. Jordan, and A. Millar. 1996. Interleukin 10 (IL-10) regulation of tumour necrosis factor alpha (TNF-alpha) from human alveolar macrophages and peripheral blood monocytes. Thorax 51:143-149.
3. Baarsch, M. J., D. L. Foss, and M. P. Murtaugh. Pathophysiological correlates of acute porcine pleuropneumonia. Am. J. Vet. Res., in press.
4. Baarsch, M. J., R. W. Scamurra, K. Burger, D. L. Foss, S. K. Maheswaran, and M. P. Murtaugh. 1995. Inflammatory cytokine expression in swine experimentally infected with Actinobacillus pleuropneumoniae. Infect. Immun. 63:3587-3594.
5. Bergeron, Y., N. Ouellet, A. M. Deslauriers, M. Simard, M. Olivier, and M. G. Bergeron. 1998. Reduction by cefodizime of the pulmonary inflammatory response induced by heat-killed Streptococcus pneumoniae in mice. Antimicrob. Agents Chemother. 42:2527-2533.
6. Bertram, T. A. 1985. Quantitative morphology of peracute pulmonary lesions in swine induced by Haemophilus pleuropneumoniae. Vet. Pathol. 22:598-609.
7. Braciak, T. A., S. K. Mittal, F. L. Graham, C. D. Richards, and J. Gauldie. 1993. Construction of recombinant human type 5 adenoviruses expressing rodent IL-6 genes. An approach to investigate in vivo cytokine function. J. Immunol. 151:5145-5153.
8. Bradley, P. P., D. A. Priebat, R D. Christensen, and G. Rothstein. 1982. Measurement of cutaneous inflammation: estimation of neutrophil content with an enzyme marker. J. Investig. Dermatol. 78:206-209.
9. Chomczynski, P., and N. Sacchi. 1987. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162:156-159.
10. Desrosiers, R. 1986. Therapeutic control and economic aspect of porcine pleuropneumonia in finishing units. Vet. Rec. 119:89-90.
11. Goldblum, S. E., B. Hennig, M. Jay, K. Yoneda, and C. J. McClain. 1989. Tumor necrosis factor alpha-induced pulmonary vascular endothelial injury. Infect. Immun. 57:1218-1226.
12. Hart, P. H., M. J. Ahern, M. D. Smith, and J. J. Finlay-Jones. 1995. Comparison of the suppressive effects of interleukin-10 and interleukin-4 on synovial fluid macrophages and blood monocytes from patients with inflammatory arthritis. Immunology 84:536-542.
13. Hart, P. H., C. A. Jones, and J. J. Finlay-Jones. 1995. Monocytes cultured in cytokine-defined environments differ from freshly isolated monocytes in their responses to IL-4 and IL-10. J. Leukoc. Biol. 57:909-918.
14. Hofstetter, C., M. Kleen, O. Habler, A. M. Allmeling, F. Krombach, and B. Zwissler. 1998. Recombinant human interleukin-10 attenuates TNFα production by porcine monocytes. Eur. J. Med. Res. 3:299-303.
15. Hopkins, S. J., and M. Humphreys. 1989. Simple, sensitive and specific bioassay of interleukin-1. J. Immunol. Methods 120:271-276.
16. Huang, H., A. A. Potter, M. Campos, F. A. Leighton, P. J. Willson, D. M. Haines, and W. D. Yates. 1999. Pathogenesis of porcine Actinobacillus pleuropneumonia, part II: roles of proinflammatory cytokines. Can. J. Vet. Res. 63:69-78.
17. Keystone, E. C., J. C. Wherry, and P. Grint. 1998. IL-10 as a therapeutic strategy in the treatment of rheumatoid arthritus. Rheum. Dis. Clin. N. Am. 24:629-639.
18. Laichalk, L., L., S. L. Kunkel, R. M. Strieter, J. M. Danforth, M. B. Bailie, and T. J. Standiford. 1996. Tumor necrosis factor mediates lung antibacterial host defense in murine Klebsiella pneumonia. Infect. Immun. 64:5211-5218.
19. Liggett, A. D., L. R. Harrison, and R. L. Farrell. 1986. Acute inflammatory effects of intratracheally instilled Escherichia coli endotoxin and sonicated suspension of Haemophilus pleuropneumoniae in swine. Can. J. Vet. Res. 50:526-531.
20. Liggett, A. D., L. R. Harrison, and R. L. Farrell. 1987. Sequential study of lesion development in experimental Haemophilus pleuropneumonia. Res. Vet. Sci. 42:204-212.
21. Lin, G., A. E. Pearson, R. W. Scamurra, Y. Zhou, M. J. Baarsch, D. J. Weiss, and M. P. Murtaugh. 1994. Regulation of interleukin-8 expression in porcine alveolar macrophages by bacterial lipopolysaccharide. J. Biol. Chem. 269: 77-85.
22. Moore, T. A., and T. J. Standiford. 1998. The role of cytokines in bacterial pneumonia: an inflammatory balancing act. Proc. Assoc. Am. Phys. 110:297-305.
23. O'Reilly, D. R., L. K. Miller, and V. A. Luckow. 1992. Baculovirus expression vectors: a laboratory manual. W. H. Freeman and Co., New York, N.Y.
24. Pampusch, M. S., A. M. Bennaars, S. Harsch, and M. P. Murtaugh. 1998. Inducible nitric oxide synthase expression in porcine immune cells. Vet. Immunol. Immunopathol. 61:279-289.
25. Pattison, I. H., D. G. Howell, and J. Elliot 1957. A haemophilus-like organism isolated from pig lung and the associated pneumonic lesion. J. Comp. Pathol. 67:320-324.
26. Rennick, D. M., M. M. Fort, and N. J. Davidson. 1997. Studies with IL-10 -/-mice: an overview. J. Leukoc. Biol. 61:389-396.
27. Rosendal, S., O. P. Miniats, and P. Sinclair. 1986. Protective efficacy of capsule extracts of Haemophilus pleuropneumoniae in pigs and mice. Vet. Microbiol. 12:229-240.
28. Sawa, T., D. B. Corry, M. A. Gropper, M. Ohara, K. Kurahashi, K. Wiener, and J. P. Kronish. 1997. IL-10 improves lung injury and survival in Pseudomonas aeruginosa pneumonia. J. Immunol. 159:2858-2866.
29. Scamurra, R. W., C. Arriaga, L. Sprunger, M. J. Baarsch, and M. P. Murtaugh. 1996. Regulation of interleukin-6 expression in porcine immune cells. J. Interferon Cytokine Res. 16:289-296.
30. Sebunya, T. N., and J. R. Saunders. 1983. Haemophilus pleuropneumoniae infection in swine: a review. J. Am. Vet. Med. Assoc. 182:1331-1337.
31. Simon, R. H., J. F. Engelhardt, Y. Yang, M. Zepeda, S. Weber-Pendleton, M. Grossman, and J. M. Wilson. 1993. Adenovirus-mediated transfer of the CFTR gene to lung of nonhuman primates: toxicity study. Hum. Gene Ther. 4:771-780.
32. Spits, H., and R. de Waal Malefyt. 1992. Functional characterization of human IL-10. Int. Arch. Allergy Immunol. 99:8-15.
33. Standiford, T. J., J. M. Wilkowski, T. H. Sisson, N. Hattori, B. Mehrad, K. A. Bucknell, and T. A. Moore. 1999. Intrapulmonary tumor necrosis factor gene therapy increases bacterial clearance and survival in murine gram-negative pneumonia. Hum. Gene Ther. 10:899-909.
34. Stephens, K. E., A. Ishizaka, Z. H. Wu, J. W. Larrick, and T. A. Raffin. 1988. Granulocyte depletion prevents tumor necrosis factor-mediated acute lung injury in guinea pigs. Am. Rev. Respir. Dis. 138:1300-1307.
35. Suter, P. M., S. Suter, E. Girardin, P. Roux-Lombard, G. E. Grau, and J. M. Dayer. 1992. High bronchoalveolar levels of tumor necrosis factor and its inhibitors, interleukin-1, interferon, and elastase, in patients with adult respiratory distress syndrome after trauma, shock, or sepsis. Am. Rev. Respir. Dis. 145:1016-1022.
36. Thomassen, M. J., L. T. Divis, and C. J. Fisher. 1996. Regulation of human alveolar macrophage inflammatory cytokine production by interleukin-10. Clin. Immunol. Immunopathol. 80:321-324.
37. Thompson-Snipes, L., V. Dhar, M. W. Bond, T. R. Mosmann, K. W. Moore, and D. M. Rennick. 1991. Interleukin 10: a novel stimulatory factor for mast cells and their progenitors. J. Exp. Med. 173:507-510.
38. Tran, V. N., B. Misset, F. Lebargy, J. Carlet, and J. F. Bernaudin. 1993. Expression of tumor necrosis factor-alpha gene in alveolar macrophages from patients with the adult respiratory distress syndrome. Am. Rev. Respir. Dis. 147:1585-1589.
39. Van der Poll, T., A. Marchant, C. V. Keogh, M. Goldman, and S. F. Lowry. 1996. Interleukin-10 impairs host defense in murine pneumococcal pneumonia. J. Infect. Dis. 174:994-1000.
40. Wilson, J. M., J. F. Engelhardt, M. Grossman, R. H. Simon, and Y. Yang. 1994. Gene therapy of cystic fibrosis lung disease using E1 deleted adenoviruses: a phase I trial. Hum. Gene Ther. 5:501-519.
41. Xing, Z., T. Braciak, M. Jordana, K. Croitoru, F. L. Graham, and J. Gauldie. 1994. Adenovirus-mediated cytokine gene transfer at tissue sites. Overexpression of IL-6 induces lymphocytic hyperplasia in the lung. J. Immunol. 153:4059-4069.
42. Zissel, G., J. Schlaak, M. Schlaak, and J. Muller-Quernheim. 1996. Regulation of cytokine release by alveolar macrophages treated with interleukin-4, interleukin-10, or transforming growth factor beta. Eur. Cytokine Netw. 7:59-66.