Synthesis of some new substituted triazolo [4,3-a][1,4] benzodiazepine derivatives as potent anticonvulsants

European Journal of Medicinal Chemistry

Volumn 41, Issue 3, 2006, Pages 417-422

  Narayana, B ^a   Vijaya Raj, K K ^a   Ashalatha, B V ^a   Kumari, N Suchetha ^b  

^a MANGALORE UNIVERSITY   (India)

^b NITTE DEEMED TO BE UNIVERSITY   (India)

Author keywords

Anticonvulsants; Synthesis; Triazolo benzodiazepine

Indexed keywords

1 (2 BROMO 5 METHOXYPHENYL) 8 CHLORO 6 (2 FLUOROPHENYL) 4H [1,2,4]TRIAZOLO[4,3 A][1,4]BENZODIAZEPINE; 8 CHLORO 6 (2 FLUOROPHENYL) 1 (4 FLUOROPHENYL) 4H [1,2,4]TRIAZOLO[4,3 A][1,4]BENZODIAZEPINE; 8 CHLORO 6 (2 FLUOROPHENYL) 1 (4 NITRO 1H INDOL 2 YL) 4H [1,2,4]TRIAZOLO[4,3 A][1,4]BENZODIAZEPINE; 8 CHLORO 6 (2 FLUOROPHENYL) 1 (6 METHOXY 2 NAPHTHYL) 4H [1,2,4]TRIAZOLO[4,3 A][1,4]BENZODIAZEPINE; 8 CHLORO 6 (2 FLUOROPHENYL) 1 PYRIDIN 3 YL 4H [1,2,4]TRIAZOLO[4,3 A][1,4]BENZODIAZEPINE; 8 CHLORO 6 (2 FLUOROPHENYL) 1 PYRIDIN 4 YL 4H [1,2,4]TRIAZOLO[4,3 A][1,4]BENZODIAZEPINE; ANTICONVULSIVE AGENT; BENZODIAZEPINE DERIVATIVE; DIAZEPAM; HYDRAZIDE DERIVATIVE; UNCLASSIFIED DRUG;

ALKALINITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTICONVULSANT ACTIVITY; ARTICLE; CONTROLLED STUDY; CONVULSION; DRUG ACTIVITY; DRUG POTENCY; DRUG SYNTHESIS; MALE; MOUSE; NONHUMAN; STRUCTURE ACTIVITY RELATION; SUBSTITUTION REACTION; ANIMAL; CHEMICAL STRUCTURE; CHEMISTRY; DRUG SCREENING; SPECTROSCOPY; SYNTHESIS;

ANIMALS; ANTICONVULSANTS; BENZODIAZEPINES; DRUG EVALUATION, PRECLINICAL; MALE; MICE; MOLECULAR STRUCTURE; SPECTRUM ANALYSIS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 33645963789     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2005.12.003     Document Type: Article

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