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33645901591
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5
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33645954341
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note
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Scifinder Scholar reveals ∼4700 structures in ∼600, mostly patent, references.
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Smith's synthesis of trienomycin A is illustrative in this regard, as nearly 25% of their total synthetic steps were dedicated to building the aromatic region of the target molecule. See: Smith, A. B., III; Barbosa, J.; Wong, W.; Wood, J. L. J. Am. Chem. Soc. 1996, 118, 8316-8328.
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33645902575
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See the Supporting Information for details
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(a) See the Supporting Information for details.
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31
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33645921700
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note
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2/acetone eluent. Evaporation followed by drying under high vacuum afforded the final product.
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33
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33645939284
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note
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The composition of the offending species removed by the silica gel plug is uncertain at this time.
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34
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33645897402
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note
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2 afforded the corresponding urea substituted phenol in only 19% yield along with adventitious Suzuki products.
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