Analysis of the CDR3 length of TCR αβ T cells in the peripheral blood of patients with chronic hepatitis B

Hepatology Research

Volumn 35, Issue 1, 2006, Pages 10-18

  Yao, Xin Sheng ^a   Zhang, Guang Wen ^a   Ma, Li ^a   Wen, Qian ^a   Hou, Jin Lin ^a   Meng, Min Jie ^a   Ma, Shi Wu ^a   Liang, Min Feng ^a   Lin, Ying ^b   Wu, Zhen Qiang ^b   He, Xiao Wei ^b   Wang, Ju Fang ^b   Wang, Xiao Ning ^a,b  

^a SOUTHERN MEDICAL UNIVERSITY   (China)

^b SOUTH CHINA UNIVERSITY OF TECHNOLOGY   (China)

Author keywords

Chronic hepatitis B (CHB); Complementarity Determining Region3 (CDR3); GeneScan; Immunoscope spectratyping technique

Indexed keywords

COMPLEMENTARY DNA; EPITOPE; HEPATITIS B VACCINE; HLA ANTIGEN; OLIGOCLONAL BAND; T LYMPHOCYTE RECEPTOR ALPHA CHAIN; T LYMPHOCYTE RECEPTOR BETA CHAIN;

ADULT; ARTICLE; CASE REPORT; COMPLEMENTARITY DETERMINING REGION; CONTROLLED STUDY; CORRELATION ANALYSIS; GENE SEQUENCE; GENETIC ANALYSIS; HEPATITIS B; HEPATITIS B VIRUS; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOTHERAPY; INDIVIDUALIZATION; LIVER BIOPSY; MALE; MULTIGENE FAMILY; NORMAL DISTRIBUTION; PERIPHERAL LYMPHOCYTE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN STRUCTURE; T LYMPHOCYTE;

EID: 33645941226     PISSN: 13866346     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.hepres.2006.01.006     Document Type: Article

References (30)

1. Guidotti L.G., Ishikawa T., Hobbs M.V., et al. Intracellular inactivation of the hepatitis B virus by cytotoxic T lymphocytes. Immunity 4 1 (1996) 25-36
2. Guidotti L.G., and Chisari F.V. To kill or to cure: options in host defense against viral infection. Curr Opin Immunol 8 4 (1996) 478-483
3. Moriyama T., Guilhot S., Klopchin K., et al. Immunobiology and pathogenesis of hepatocellular injury in hepatitis B virus transgenic mice. Science 248 4953 (1990) 361-364
4. Lim A., Baron V., Ferradini L., et al. Combination of MHC-peptide multimer-based T cell sorting with the Immunoscope permits sensitive ex vivo quantitation and follow-up of human CD8+T cell immune responses. J Immunol Methods 261 1-2 (2002) 177-194
5. Davis M.M., and Bjorkman P.J. T-Cell antigen receptor genes and T-cell recognition. Nature 334 6181 (1988) 395-402
6. Fields B.A., Ober B., Malchiodi E.L., et al. Crystal structure of the V· domain of a T cell antigen receptor. Science 270 (1995) 1821-1824
7. Borght A.V., Geusens P., Vandevyver C., et al. Skewed T-cell receptor variable gene usage in the synovium of early and chronic rheumatoid arthritis patients and persistence of clonally expanded T-cells in a chronic patient. Rheumatology 39 (2000) 1189-1201
8. Pira G.L., Bottone L., and Fenoglio D. Analysis of the antigen specific T-cell repertoire in HIV infection. Immunol Lett 79 (2001) 85-91
9. Maini M.K., Reignat S., and Boni C. T cell receptor usage of virusspecific CD8 cells and recognition of viral mutations during acute and persistent hepatitis B virus infection. Eur J Immunol 30 (2000) 3067-3078
10. Peng J., Luo K., Zhu Y., Guo Y., Zhang L., and Hou J. Clinical and histological characteristics of chronic hepatitis B with negative hepatitis B e-antigen. Chin Med J 116 9 (2003) 1312-1317
11. Han M., Harrison L., Kehn P., et al. Invariant or highly conserved TCR alpha are expressed on double-negative (CD3+CD4-CD8-) and CD8+ T cells. J Immunol 163 1 (1999) 301-311
12. Manfras B.J., Rudert W.A., Trucco M., et al. Analysis of the alpha/beta T-cell receptor repertoire by competitive and quantitative family-specific PCR with exogenous standards and high resolution fluorescence based CDR3 size imaging. J Immunol Methods 210 2 (1997) 235-249
13. Ikeda H., Sato N., Matsuura A., et al. Analysis of T-cell receptor V region gene usage of cytotoxic T-lymphocytes and tumor infiltrating lymphocytes derived from human autologous gastric signet ringcell carcinomas. Cancer Res 53 13 (1993) 3078-3084
14. Uko G.P., Fraser P.A., Awdeh Z.L., et al. Hepatitis B surface antigen-and tetanus toxoid-specific clonal expansion of CD4+ cells in vitro determined by TCRBV CDR3 length and nucleotide sequence. Genes Immun 2 1 (2001) 11-19
15. Garboczi D.N., Ghosh P., Utz U., et al. Structure of the complex between human T-cell receptor, viral peptide and HLA-A2. Nature 384 6605 (1996) 134-141
16. Garcia K.C., Degano M., Stanfield R.L., et al. An alphabeta T cell receptor structure at 2.5 A and its orientation in the TCR-MHC complex. Science 274 5285 (1996) 209-219
17. Housset D., Mazza G., Gregoire C., et al. The three-dimensional structure of a T-cell antigen receptor V alpha V beta heterodimer reveals a novel arrangement of the V beta domain. EMBO J 16 14 (1997) 4205-4216
18. Li H., Lebedeva M.I., Llera A.S., et al. Structure of the Vdelta domain of a human gammadelta T-cell antigen receptor. Nature 391 6666 (1998) 502-506
19. Ishikawa T., Kono D., Chung J., et al. Polyclonality and multispecificity of the CTL response to a single viral epitope. J Immunol 161 11 (1998) 5842-5850
20. Wai C.T., and Fontana R.J. Clinical significance of hepatitis B virus genotypes, variants, and mutants. Clin Liver Dis 8 2 (2004) 321-352
21. Maru Y., Yokosuka O., Imazeki F., et al. Analysis of T cell receptor variable regions and complementarity determining region 3 of infiltrating T lymphocytes in the liver of patients with chronic type B hepatitis. Intervirology 46 5 (2003) 277-288
22. Heath W.R., Carbone F.R., Bertolino P., et al. Expression of two T cell receptor alpha chains on the surface of normal murine T cells. Eur J Immunol 25 (1995) 1617-1623
23. Shokri F., and Amani A. High rate seroconversion following administration of a single supplementary dose of recombinant hepatitis B vaccine in Iranian healthy non-responder neonates. Med Microbiol Immunol 185 (1997) 231-235
24. Elliott J.I., and Altmann D.M. Dual T cell receptor alpha chain T cells in autoimmunity. J Exp Med 182 (1995) 953-959
25. Selin L.K., Varga S.M., Wong I.C., et al. Protective heterologous antiviral immunity and enhanced immunopathogenesis mediated by memory T cell populations. J Exp Med 188 (1998) 1705-1715
26. Tsai S.L., Chen Y.M., Chen M.H., et al. Hepatitis C virus variants circumventing cytotoxic T lymphocyte activity as a mechanism of chronicity. Gastroenterology 115 4 (1998) 954-965
27. Jenson H. Non-responders to Hepatitis B vaccine. Postgrad Med 107 (2000) 97
28. Shokri F., and Jafarzadeh A. High seroprotection rate induced by low doses of a recombinant hepatitis B vaccine in healthy Iranian neonates. Vaccine 14 (2001) 4544-4548
29. Umemura T., Yoshizawa K., Ota M., et al. Analysis of T cell repertoire in the liver of patients with chronic hepatitis C. Clin Exp Immunol 121 (2000) 120-126
30. Zuckerman J., Zuckerman A., Du Symington I.W., et al. Williams A, Dickson B. Evaluation of new hepatitis B triple-antigen vaccine in inadequated responders to current vaccine. Hepatology 34 (2001) 798-802