Differential Distribution of CD4+CD25bright and CD8+CD28- T-cells in Decidua and Maternal Blood During Human Pregnancy

Placenta

Volumn 27, Issue SUPPL., 2006, Pages 47-53

  Tilburgs, T ^a   Roelen, D L ^a   van der Mast, B J ^a   van Schip, J J ^a   Kleijburg, C ^a   de Groot Swings, G M ^a   Kanhai, H H H ^a   Claas, F H J ^a   Scherjon, S A ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Decidua; Human; Pregnancy; Regulatory T cells; Reproductive immunology; T cells

Indexed keywords

CD28 ANTIGEN; CD4 ANTIGEN; CD8 ANTIGEN; INTERLEUKIN 2 RECEPTOR ALPHA;

ADULT; ARTICLE; CELL SPECIFICITY; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DECIDUA; EMBRYO; FEMALE; FIRST TRIMESTER PREGNANCY; GESTATION PERIOD; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNE RESPONSE; IMMUNOMODULATION; IMMUNOREGULATION; MATERNAL BLOOD; PHENOTYPIC VARIATION; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; SUPPRESSOR CELL; T LYMPHOCYTE SUBPOPULATION;

ANTIGENS, CD28; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; DECIDUA; FEMALE; HUMANS; PREGNANCY; RECEPTORS, INTERLEUKIN-2; T-LYMPHOCYTE SUBSETS; T-LYMPHOCYTES; T-LYMPHOCYTES, REGULATORY;

EID: 33645921648     PISSN: 01434004     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.placenta.2005.11.008     Document Type: Article

References (22)

1. Tafuri A., Alferink J., Moller P., Hammerling G.J., and Arnold B. T cell awareness of paternal alloantigens during pregnancy. Science 270 (1995) 630-633
2. Jiang S.P., and Vacchio M.S. Multiple mechanisms of peripheral T cell tolerance to the fetal "allograft". J Immunol 160 (1998) 3086-3090
3. Aluvihare V.R., Kallikourdis M., and Betz A.G. Regulatory T cells mediate maternal tolerance to the fetus. Nat Immunol 5 (2004) 266-271
4. Sasaki Y., Sakai M., Miyazaki S., Higuma S., Shiozaki A., and Saito S. Decidual and peripheral blood CD4+CD25+ regulatory T cells in early pregnancy subjects and spontaneous abortion cases. Mol Hum Reprod 10 (2004) 347-353
5. Winkler M., Fischer D.C., Ruck P., Marx T., Kaiserling E., Oberpichler A., et al. Parturition at term: parallel increases in interleukin-8 and proteinase concentrations and neutrophil count in the lower uterine segment. Hum Reprod 14 (1999) 1096-1100
6. Le Bouteiller P., Rodriguez A.M., Mallet V., Girr M., Guillaudeux T., and Lenfant F. Placental expression of HLA class I genes. Am J Reprod Immunol 35 (1996) 216-225
7. Plouzek C.A., Leslie K.K., Stephens J.K., and Chou J.Y. Differential gene expression in the amnion, chorion, and trophoblast of the human placenta. Placenta 14 (1993) 277-285
8. Sindram-Trujillo A.P., Scherjon S.A., Hulst-van Miert P.P., van Schip J.J., Kanhai H.H.H., Roelen D.L., et al. Differential distribution of NK cells in decidua basalis compared with decidua parietalis after uncomplicated human term pregnancy. Hum Immunol 64 (2003) 921-929
9. Sindram-Trujillo A., Scherjon S., Kanhai H., Roelen D., and Claas F. Increased T-cell activation in decidua parietalis compared to decidua basalis in uncomplicated human term pregnancy. Am J Reprod Immunol 49 (2003) 261-268
10. O'Garra A., and Vieira P. Regulatory T cells and mechanisms of immune system control. Nat Med 10 (2004) 801-805
11. Sakaguchi S., Sakaguchi N., Shimizu J., Yamazaki S., Sakihama T., Itoh M., et al. Immunologic tolerance maintained by CD25+ CD4+ regulatory T cells: their common role in controlling autoimmunity, tumor immunity, and transplantation tolerance. Immunol Rev 182 (2001) 18-32
12. Chang C.C., Ciubotariu R., Manavalan J.S., Yuan J., Colovai A.I., Piazza F., et al. Tolerization of dendritic cells by T(S) cells: the crucial role of inhibitory receptors ILT3 and ILT4. Nat Immunol 3 (2002) 237-243
13. Moffett-King A. Natural killer cells and pregnancy. Nat Rev Immunol 2 (2002) 656-663
14. Loken M.R., Brosnan J.M., Bach B.A., and Ault K.A. Establishing optimal lymphocyte gates for immunophenotyping by flow cytometry. Cytometry 11 (1990) 453-459
15. Petroff M.G., Kharatyan E., Torry D.S., and Holets L. The immunomodulatory proteins B7-DC, B7-H2, and B7-H3 are differentially expressed across gestation in the human placenta. Am J Pathol 167 (2005) 465-473
16. Heikkinen J., Mottonen M., Alanen A., and Lassila O. Phenotypic characterization of regulatory T cells in the human decidua. Clin Exp Immunol 136 (2004) 373-378
17. Somerset D.A., Zheng Y., Kilby M.D., Sansom D.M., and Drayson M.T. Normal human pregnancy is associated with an elevation in the immune suppressive CD25+ CD4+ regulatory T-cell subset. Immunology 112 (2004) 38-43
18. Polanczyk M.J., Carson B.D., Subramanian S., Afentoulis M., Vandenbark A.A., Ziegler S.F., et al. Cutting edge: estrogen drives expansion of the CD4+CD25+ regulatory T cell compartment. J Immunol 173 (2004) 2227-2230
19. Koopman L.A., Kopcow H.D., Rybalov B., Boyson J.E., Orange J.S., Schatz F., et al. Human decidual natural killer cells are a unique NK cell subset with immunomodulatory potential. J Exp Med 198 (2003) 1201-1212
20. Hiby S.E., Walker J.J., O'shaughnessy K.M., Redman C.W., Carrington M., Trowsdale J., et al. Combinations of maternal KIR and fetal HLA-C genes influence the risk of preeclampsia and reproductive success. J Exp Med 200 (2004) 957-965
21. Hori S., Nomura T., and Sakaguchi S. Control of regulatory T cell development by the transcription factor Foxp3. Science 299 (2003) 1057-1061
22. Vieira P.L., Christensen J.R., Minaee S., O'Neill E.J., Barrat F.J., Boonstra A., et al. IL-10-secreting regulatory T cells do not express Foxp3 but have comparable regulatory function to naturally occurring CD4+CD25+ regulatory T cells. J Immunol 172 (2004) 5986-5993