Synthesis and in vitro antibacterial activity of some N-(5-aryl-1,3,4-thiadiazole-2-yl)piperazinyl quinolone derivatives

Farmaco

Volumn 58, Issue 10, 2003, Pages 1023-1028

  Foroumadi, Alireza ^a   Soltani, Fatemeh ^a   Moshafi, Mohammad Hasan ^a   Ashraf Askari, Rogheeyeh ^a  

^a KERMAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Antibacterial activity; Minimum inhibitory concentration; N Piperazinyl quinolones

Indexed keywords

1 CYCLOPROPYL 6 FLUORO 7 [4 [5 (1 METHYL 5 NITRO 2 IMIDAZOLYL) 1,3,4 THIADIAZOL 2 YL] 1 PIPERAZINYL] 4 OXO 1,4 DIHYDRO 3 QUINOLINE CARBOXYLIC ACID; 1 CYCLOPROPYL 6 FLUORO 7 [4 [5 (2 NITROPHENYL) 1,3,4 THIADIAZOL 2 YL] 1 PIPERAZINYL] 4 OXO 1,4 DIHYDRO 3 QUINOLINE CARBOXYLIC ACID; 1 CYCLOPROPYL 6 FLUORO 7 [4 [5 (3 NITROPHENYL) 1,3,4 THIADIAZOL 2 YL] 1 PIPERAZINYL] 4 OXO 1,4 DIHYDRO 3 QUINOLINE CARBOXYLIC ACID; 1 CYCLOPROPYL 6 FLUORO 7 [4 [5 (4 NITROPHENYL) 1,3,4 THIADIAZOL 2 YL] 1 PIPERAZINYL] 4 OXO 1,4 DIHYDRO 3 QUINOLINE CARBOXYLIC ACID; 1 ETHYL 6 FLUORO 7 [4 [5 (1 METHYL 5 NITRO 2 IMIDAZOLYL) 1,3,4 THIADIAZOL 2 YL] 1 PIPERAZINYL] 4 OXO 1,4 DIHYDRO 1,8 NAPHTHYRIDINE 3 CARBOXYLIC ACID; 1 ETHYL 6 FLUORO 7 [4 [5 (1 METHYL 5 NITRO 2 IMIDAZOLYL) 1,3,4 THIADIAZOL 2 YL] 1 PIPERAZINYL] 4 OXO 1,4 DIHYDRO 3 QUINOLINE CARBOXYLIC ACID; 1 ETHYL 6 FLUORO 7 [4 [5 (2 NITROPHENYL) 1,3,4 THIADIAZOL 2 YL] 1 PIPERAZINYL] 4 OXO 1,4 DIHYDRO 1,8 NAPHTHYRIDINE 3 CARBOXYLIC ACID; 1 ETHYL 6 FLUORO 7 [4 [5 (2 NITROPHENYL) 1,3,4 THIADIAZOL 2 YL] 1 PIPERAZINYL] 4 OXO 1,4 DIHYDRO 3 QUINOLINE CARBOXYLIC ACID; 1 ETHYL 6 FLUORO 7 [4 [5 (3 NITROPHENYL) 1,3,4 THIADIAZOL 2 YL] 1 PIPERAZINYL] 4 OXO 1,4 DIHYDRO 1,8 NAPHTHYRIDINE 3 CARBOXYLIC ACID; 1 ETHYL 6 FLUORO 7 [4 [5 (3 NITROPHENYL) 1,3,4 THIADIAZOL 2 YL] 1 PIPERAZINYL] 4 OXO 1,4 DIHYDRO 3 QUINOLINE CARBOXYLIC ACID; 1 ETHYL 6 FLUORO 7 [4 [5 (4 NITROPHENYL) 1,3,4 THIADIAZOL 2 YL] 1 PIPERAZINYL] 4 OXO 1,4 DIHYDRO 1,8 NAPHTHYRIDINE 3 CARBOXYLIC ACID; 1 ETHYL 6 FLUORO 7 [4 [5 (4 NITROPHENYL) 1,3,4 THIADIAZOL 2 YL] 1 PIPERAZINYL] 4 OXO 1,4 DIHYDRO 3 QUINOLINE CARBOXYLIC ACID; BENZENE DERIVATIVE; CIPROFLOXACIN; ENOXACIN; NITROIMIDAZOLE DERIVATIVE; NORFLOXACIN; QUINOLINE DERIVATIVE; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG SCREENING; DRUG SYNTHESIS; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; IN VITRO STUDY; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS EPIDERMIDIS;

EID: 0141737751     PISSN: 0014827X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-827X(03)00191-5     Document Type: Article

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