The effect of skin permeation enhancers on the formation of porphyrins in mouse skin during topical application of the methyl ester of 5-aminolevulinic acid

Journal of Photochemistry and Photobiology B: Biology

Volumn 83, Issue 2, 2006, Pages 94-97

  Bugaj, Andrzej ^a,b   Juzeniene, Asta ^b   Juzenas, Petras ^b   Iani, Vladimir ^b   Ma, Li Wei ^b   Moan, Johan ^b,c  

^a POZNAN UNIVERSITY OF MEDICAL SCIENCES   (Poland)

^b OSLO UNIVERSITY HOSPITAL   (Norway)

^c UNIVERSITY OF OSLO   (Norway)

Author keywords

In vivo direct skin fluorescence measurement; Methyl 5 aminolevulinate; Normal mouse skin fluorescence; Permeation enhancers; Porphyrins; Topical application

Indexed keywords

1 [2 (DECYLTHIO)ETHYL]AZACYCLOPENTAN 2 ONE; AMINOLEVULINIC ACID METHYL ESTER; DIETHYLENE GLYCOL MONOETHYL ETHER; DIMETHYL SULFOXIDE; LABRASOL; PENETRATION ENHANCING AGENT; PORPHYRIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONCENTRATION (PARAMETERS); CONCENTRATION RESPONSE; CONTROLLED STUDY; CREAM; DRUG PENETRATION; FEMALE; FLUORESCENCE SPECTROSCOPY; MOUSE; NONHUMAN; PHOTODYNAMIC THERAPY; PRIORITY JOURNAL; SKIN IRRITATION; SKIN PENETRATION; SKIN PERMEABILITY;

ADMINISTRATION, TOPICAL; AMINOLEVULINIC ACID; ANIMALS; DIMETHYL SULFOXIDE; FEMALE; FLUORESCENCE; KINETICS; MICE; MICE, INBRED BALB C; MICE, NUDE; PERMEABILITY; PHOTOCHEMOTHERAPY; PORPHYRINS; PYRROLES; SKIN;

ANIMALIA;

EID: 33645871583     PISSN: 10111344     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jphotobiol.2005.12.003     Document Type: Article

References (20)

1. Kennedy J.C., Marcus S.L., and Pottier R.H. Photodynamic therapy (PDT) and photodiagnosis (PD) using endogenous photosensitization induced by 5-aminolevulinic acid (ALA): mechanism and clinical results. J. Clin. Laser Med. Surg. 14 (1996) 289-304
2. Peng Q., Warloe T., Berg K., Moan J., Kongshaug M., Giercksky K.E., and Nesland J.M. 5-aminolevulinic acid-based photodynamic therapy. Clinical research and future challenges. Cancer 79 (1997) 2282-2308
3. Peng Q., Berg K., Moan J., Kongshaug M., and Nesland J.M. 5-aminolevulinic acid-based photodynamic therapy: principles and experimental research. Photochem. Photobiol. 65 (1997) 235-251
4. Peng Q., Moan J., Warloe T., Iani V., Steen H.B., Bjørseth A., and Nesland J.M. Build-up of esterified aminolevulinic-acid-derivative-induced porphyrin fluorescence in normal mouse skin. J. Photochem. Photobiol. B 65 (1997) 235-251
5. Moan J., Ma L.W., Juzeniene A., Iani V., Juzenas P., Apricena F., and Peng Q. Pharmacology of protoporphyrin IX in nude mice after application of ALA and ALA esters. Int. J. Cancer 103 (2003) 132-135
6. van den Akker J., Iani V., Star W., Sterenborg H.J.C.M., and Moan J. Topical application of 5-aminolevulinic acid to normal nude mouse skin: differences in protoporphyrin IX fluorescence kinetics and the role of the stratum corneum. Photochem. Photobiol. 72 (2000) 681-689
7. Ziółkowski P., Osiecka B.J., Oremek G., Siewiński M., Symonowicz K., Saleh Y., and Bronowicz A. Enhancement of photodynamic therapy by use of aminolevulinic acid/glycolic acid drug mixture. J. Exp. Ther. Oncol. 4 (2004) 21-129
8. Harth Y., Hirshowitz B., and Kaplan B. Modified topical photodynamic therapy of superficial skin tumours, utilizing aminolevulinic acid, penetration enhancers, red light and hyperthermia. Dermatol. Surg. 24 (1998) 723-726
9. de Rosa F.S., Lopez R.F.V., Thomazini J.S., Tedesco A.C., Lange N., and Bentley M.V.L.B. In vitro metabolism of 5-ALA esters derivatives in hairless mice skin homogenate and in vivo PPIX accumulation studies. Pharm. Res. 21 (2004) 2247-2252
10. Casas A., Perotti C., Fukuda H., Rogers L., Butler A.R., and Batlle A.M.C. ALA and ALA hexyl ester induced porphyrin synthesis in chemically induced skin tumors: the role of different vehicles on improving photosensitization. Br. J. Cancer 85 (2001) 1794-1800
11. Strickley R.G. Solubilizing excipients in oral and injectable formulations. Pharm. Res. 21 (2004) 201-230
12. Williams A.C., and Barry B.W. Penetration enhancers. Adv. Drug Deliv. Rev. 56 (2004) 603-618
13. Kim H.J., Yoon K.A., Hahn M., Park E.S., and Chi S.C. Preparation and in vitro evaluation of self-microemulsifying drug delivery systems containing idebenone. Drug Dev. Ind. Pharm. 26 (2000) 523-529
14. Kommuru T.R., Gurley B., Khan M.A., and Reddy I.K. Self-emulsifying drug delivery systems (SEDDS) of coenzyme Q10: formulation, development and bioavailability assessment. Int. J. Pharm. 212 (2001) 233-246
15. Minkov I., Ivanova T., Panaiotov I., Proust J., and Saulnier P. Reorganization of lipid nanocapsules at air-water interface Part 2. Properties of the formed surface film. Colloids Surf. B Biointerfaces 44 (2005) 97-203
16. Minkov I., Ivanova T., Panaiotov I., Proust J., and Verger R. Reorganization of lipid nanocapsules at air-water interface Part 3. Action of hydrolytic enzymes HLL and pancreatic PLA(2). Colloids Surf. B Biointerfaces 45 (2005) 24-34
17. Yano T., Furukawa K., Tsuji M., Noda K., and Otagiri M. Evaluation of a new penetration enhancer 1-[2-(decylthio)ethyl]azacyclopentan-2-one (HPE-101). J. Pharmacobiodyn. 155 (1992) 27-533
18. Yano T., Higo N., Fukuda K., Tsuji M., Noda K., and Otagiri M. Further evaluation of a new penetration enhancer, HPE-101. J. Pharm. Pharmacol. 45 (1993) 775-778
19. Zhang Q., Jiang X., Jiang W., Lu W., Su L., and Shi Zh. Preparation of nimodipine-loaded microemulsion for intranasal delivery and evaluation on the targeting efficiency to the brain. Int. J. Pharm. 275 (2004) 85-96
20. T.M. Hsu, E. Jacobson, R.C. LoBello, E.C. Luo, Dual enhancer composition for topical and transdermal drug. US Patent no. 6835392: 2004.