ALA and ALA hexyl ester-induced porphyrin synthesis in chemically induced skin tumours: The role of different vehicles on improving photosensitization

British Journal of Cancer

Volumn 85, Issue 11, 2001, Pages 1794-1800

  Casas, A ^a   Perotti, C ^a   Fukuda, H ^a   Rogers, L ^b   Butler, A R ^b   Batlle, A ^a  

^a UNIVERSIDAD DE BUENOS AIRES   (Argentina)

^b UNIVERSITY OF ST ANDREWS   (United Kingdom)

Author keywords

ALA; ALA esters; Photodynamic therapy; Squamous papillomas

Indexed keywords

ALCOHOL; AMINOLEVULINIC ACID; AMINOLEVULINIC ACID HEXYL ESTER; DIMETHYL SULFOXIDE; DRUG VEHICLE; PORPHYRIN; PROTOPORPHYRIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD; CHEMICAL CARCINOGENESIS; CONCENTRATION RESPONSE; CONTROLLED STUDY; CREAM; DRUG FORMULATION; DRUG POTENTIATION; DRUG SYNTHESIS; FEMALE; LIVER; MOUSE; NONHUMAN; PHOTODYNAMIC THERAPY; PHOTOSENSITIZATION; PORPHYRIN METABOLISM; PRIORITY JOURNAL; SKIN; SKIN PAPILLOMA; SKIN TUMOR; SPLEEN; SQUAMOUS CELL; TISSUE SPECIFICITY; TUMOR LOCALIZATION;

9,10-DIMETHYL-1,2-BENZANTHRACENE; AMINOLEVULINIC ACID; ANIMALS; FEMALE; KIDNEY; LIVER; MICE; NEOPLASMS, EXPERIMENTAL; PAPILLOMA; PHOTOCHEMOTHERAPY; PROTOPORPHYRINS; SKIN; SKIN NEOPLASMS; SPLEEN;

EID: 0035977196     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1054/bjoc.2001.2156     Document Type: Article

References (21)

1. Treatment of psoriasis by topical photodynamic therapy with polychromatic light
2. Approach to risk assessment for genotoxic carcinogens based on data from the mouse skin initiation-promotion model
3. Tissue distribution and kinetics of endogenous porphyrins synthesized after topical application of ALA in different vehicles
4. Comparative effect of ALA derivatives on Protoporphyrin IX production in human and rat skin organ cultures
5. The influence of the vehicle on the synthesis of porphyrins after topical application of 5-aminolevulinic acid. Implications in cutaneous photodynamic sensitization
6. Terapia fotodinámica en el tratamiento de tumores de piel inducidos quámicamente
7. Photosensitisation and mechanism of cytotoxicity induced by the use of ALA derivatives in photodynamic therapy
8. Photodynamic therapy (PDT) of malignant tumors
9. Photodynamic diagnosis and therapy in dermatology
10. Tumor-localizing properties of porphyrins. In vivo studies using free and liposome encapsulated aminolevulinic acid
11. Use of 5-aminolevulinic acid esters to improve photodynamic therapy on cells in culture
12. Photodynamic therapy with endogenous protoporphyrin IX: Basic principles and present clinical experience
13. Prodrugs for 5-aminolevulinic acid for photodynamic therapy
14. Derivatives of 5-aminolevulinic acid for photodynamic therapy: Enzymatic conversion into protoporphyrin
15. The role of photodynamic therapy in dermatology
16. Distribution of 5-aminolevulinic acid-induced porphyrins in noduloulcerative basal cell carcinoma
17. Build-up of esterified aminolevulinic-acid-derivative-induced porphyrin fluorescence in normal mouse skin
18. Correlations between horny layer concentration and percutaneous absorption
19. Protoporphyrin IX fluorescence kinetics and localization after topical application of ALA pentyl ester and ALA on hairless mouse skin with UVB-induced early skin cancer
20. Topical application of 5-aminolevulinic acid hexyl ester and 5-aminolevulinic to normal nude mouse skin: Differences in protoporphyrin IX fluorescence kinetics and the role of the stratum corneum