Mechanisms underlying lipopolysaccharide-induced kinin B1 receptor up-regulation in the pig iris sphincter in vitro

Molecular Pharmacology

Volumn 69, Issue 5, 2006, Pages 1701-1708

  El Sayah, Mariem ^a   Medeiros, Rodrigo ^a   Fernandes, Elizabeth S ^a   Campos, Maria M ^a   Calixto, Jõao B ^a  

^a FEDERAL UNIVERSITY OF SANTA CATARINA   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; BRADYKININ B1 RECEPTOR; CYCLOHEXIMIDE; DACTINOMYCIN; DEXAMETHASONE; ESCHERICHIA COLI LIPOPOLYSACCHARIDE; I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE P38; MITOGEN ACTIVATED PROTEIN KINASE P38 INHIBITOR; PROTEIN SYNTHESIS INHIBITOR; PYRROLIDINEDITHIOCARBAMATE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; IN VITRO STUDY; MOLECULAR BIOLOGY; MUSCLE CONTRACTILITY; NONHUMAN; PRIORITY JOURNAL; RECEPTOR UPREGULATION; SIGNAL TRANSDUCTION; SPHINCTER PUPILLAE MUSCLE; STIMULATION; SWINE;

ANIMALS; BRADYKININ; CYCLOHEXIMIDE; IRIS; KINETICS; LIPOPOLYSACCHARIDES; RECEPTOR, BRADYKININ B1; SWINE; UP-REGULATION;

EID: 33645806322     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.105.021097     Document Type: Article

References (41)

1. Beutler B (2002) Toll-like receptors: how they work and what they do. Curr Opin Hematol 9:2-10.
2. Beutler B and Rietschel ET (2003) Innate immune sensing and its roots: the story of endotoxin. Nat Rev Immunol 3:169-176.
3. Cabrini DA, Kyle DJ, and Calixto JB (1996) A pharmacological analysis of receptor subtypes and the mechanisms mediating the biphasic response induced by kinins in the rat stomach fundus in vitro. J Pharmacol Exp Ther 277:299-307.
4. Calixto JB, Cabrini DA, Ferreira J, and Campos MM (2000) Kinins in pain and inflammation. Pain 87:1-5.
5. Calixto JB, Cabrini DA, Ferreira J, and Campos MM (2001) Inflammatory pain: kinins and antagonists. Curr Opin Anaesthesiol 14:519-526.
6. 1 receptors: key G-protein-coupled receptors and their role in inflammatory and painful processes. Br J Pharmacol 143:803-818.
7. 9-BK-induced rat paw oedema by systemic treatment with bacterial endotoxin. Br J Pharmacol 117:793-798.
8. 1 kinin-receptor up-regulation. Evidence for involvement of protein kinases and nuclear factor kappaB pathways. Br J Pharmacol 127:1851-1859.
9. Chi ZL, Hayasaka S, Zhang XY, Hayasaka Y, and Cui HS (2004) Effects of rolipram, a selective inhibitor of type 4 phosphodiesterase, on lipopolysaccharide-induced uveitis in rats. Investig Ophthalmol Vis Sci 45:2497-2502.
10. El Sayah M and Calixto JB (2003a) New evidence on the mechanisms underlying bradykinin-mediated contraction of the pig iris sphincter in vitro. Peptides 24:1045-1051.
11. El Sayah M and Calixto JB (2003b) Study of the mechanisms involved in the bradykinin-induced contraction of the pig iris sphincter muscle in vitro. Eur J Pharmacol 458:175-181.
12. Fang IM, Yang CH, Lin CP, Yang CM, and Chen MS (2005) Effects of pyrrolidine dithiocarbamate, an NF-kappaB inhibitor, on cytokine expression and ocular inflammation in experimental autoimmune anterior uveitis. J Ocul Pharmacol Ther 21:95-106.
13. 1 receptors in the rat paw. Br J Pharmacol 139:973-981.
14. Geppetti P, Patacchini R, Cecconi R, Tramontana M, Meini S, Romani A, Nardi M, and Maggi CA (1990) Effects of capsaicin, tachykinins, calcitonin gene-related peptide and bradykinin in the pig iris sphincter muscle. Naunyn-Schmiedeberg's Arch Pharmacol 341:301-307.
15. 2 release, nociceptor stimulation and contraction of the iris sphincter muscle in the rabbit. Br J Pharmacol 92:333-340.
16. 2 receptor antagonist WIN 64338 in vivo and in vitro. Br J Pharmacol 116:3164-3268.
17. 1 receptor. Int Immunopharmacol 2:1747-1754.
18. Hwang D, Jang BC, Yu G, and Boudreau M (1997) Expression of mitogen-inducible cyclooxygenase induced by lipopolysaccharide: mediation through both mitogen-activated protein kinase and NF-kappaB signaling pathways in macrophages. Biochem Pharmacol 54:87-96.
19. 1 receptor gene transcription after heat stress in rat vascular smooth muscle cells. Int Immunopharmacol 1:533-538.
20. 1 receptors induced by tissue injury. J Immunol 160:1419-1426.
21. 1 receptor. Br J Pharmacol 131:885-892.
22. Lawrence T, Gilroy DW, Colville-Nash PR, and Willoughby DA (2001) Possible new role for NF-κB in the resolution of inflammation. Nat Med 7:1291-1297.
23. Leeb-Lundberg LM, Marceau F, Muller-Esterl W, Pettibone DJ, and Zuraw BL (2005) International union of pharmacology. XLV. Classification of the kinin receptor family: from molecular mechanisms to pathophysiological consequences. Pharmacol Rev 57:27-77.
24. Liebmann C (2001) Bradykinin signalling to MAP kinase: cell-specific connections versus principle mitogenic pathways. Biol Chem 382:49-55.
25. 1 receptors for kinins. Pharmacol Rev 50:357-386.
26. 1 receptor-mediated contraction of the rabbit aorta. Regul Pept 97:121-130.
27. 1 receptor expression induced by tissue damage in the rat portal vein: a critical role for mitogen-activated protein kinase and nuclear factor-kappaB signaling pathways. Circ Res 94:1375-1382.
28. Miyake K (2004) Innate recognition of lipopolysaccharide by Toll-like receptor 4-MD-2. Trends Microbiol 12:186-192.
29. Moreau ME, Garbacki N, Molinaro G, Brown NJ, Marceau F, and Adam A (2005) The kallikrein-kinin system: current and future pharmacological targets. J Pharmacol Sci 99:6-38.
30. 1 receptor. Biochim Biophys Acta 1442:177-185.
31. Ohta K, Nakayama K, Kurokawa T, Kikuchi T, and Yoshimura N (2002) Inhibitory effects of pyrrolidine dithiocarbamate on endotoxin-induced uveitis in Lewis rats. Investig Ophthalmol Vis Sci 43:744-750.
32. 1 in human lung fibroblasts. Mol Pharmacol 56:325-333.
33. Regoli D and Barabé J (1980) Pharmacology of bradykinin and related kinins. Pharmacol Rev 32:1-46.
34. 1 receptor in fresh or cultured rabbit aortic smooth muscle: role of NF-kappa B. Am J Physiol 283:H227-H237.
35. 1 receptor in isolated human umbilical vein: an experimental model of the in vitro up-regulation. Acta Pharmacol Sin 21:105-110.
36. 1-receptor in cultured human lung fibroblasts. J Clin Investig 101:2080-2091.
37. 1 bradykinin receptors and carboxypeptidase M are both upregulated in the aorta of pigs after LPS infusion. Biochem Biophys Res Commun 243:246-252.
38. 1 kinin receptor activity in pigs is associated with pre-existing infection. Immunopharmacology 40:49-55.
39. Wang ZY and Hakanson R (1992) Effect of resiniferatoxin on the isolated rabbit iris sphincter muscle: comparison with capsaicin and bradykinin. Eur J Pharmacol 213:235-241.
40. 1 antagonists. J Med Chem 46:1803-1806.
41. Yang CH, Fang IM, Lin CP, Yang CM, and Chen MS (2005) Effects of the NF-kappaB inhibitor pyrrolidine dithiocarbamate on experimentally induced autoimmune anterior uveitis. Investig Ophthalmol Vis Sci 46:1339-1347.