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Volumn 290, Issue 4, 2006, Pages

Iron imports. VI. HFE and regulation of intestinal iron absorption

Author keywords

Hemochromatosis; Hepatocytes; Hepcidin; Liver; Transferrin receptor

Indexed keywords

HEPCIDIN; HFE PROTEIN;

EID: 33645801416     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.00486.2005     Document Type: Review
Times cited : (39)

References (41)
  • 2
    • 0029856326 scopus 로고    scopus 로고
    • Control of iron absorption
    • Anderson GJ. Control of iron absorption. J Gastroenterol Hepatol 11: 1030-1032, 1996.
    • (1996) J Gastroenterol Hepatol , vol.11 , pp. 1030-1032
    • Anderson, G.J.1
  • 3
    • 0032427653 scopus 로고    scopus 로고
    • Kupffer cell staining by an HFE-specific monoclonal antibody: Implications for hereditary haemochromatosis
    • Bastin JM, Jones M, O'Callaghan CA, Schimanski L, Mason DY, and Townsend AR. Kupffer cell staining by an HFE-specific monoclonal antibody: implications for hereditary haemochromatosis. Br J Haematol 103: 931-941, 1998.
    • (1998) Br J Haematol , vol.103 , pp. 931-941
    • Bastin, J.M.1    Jones, M.2    O'Callaghan, C.A.3    Schimanski, L.4    Mason, D.Y.5    Townsend, A.R.6
  • 4
    • 0034610781 scopus 로고    scopus 로고
    • Crystal structure of the hereditary haemochromatosis protein HFE complexed with transferrin receptor
    • Bennett MJ, Lebron JA, and Bjorkman PJ. Crystal structure of the hereditary haemochromatosis protein HFE complexed with transferrin receptor. Nature 403: 46-53, 2000.
    • (2000) Nature , vol.403 , pp. 46-53
    • Bennett, M.J.1    Lebron, J.A.2    Bjorkman, P.J.3
  • 6
    • 15244342393 scopus 로고    scopus 로고
    • The hereditary hemochromatosis protein, HFE, lowers intracellular iron levels independently of transferrin receptor 1 in TRVb cells
    • Carlson H, Zhang AS, Fleming WH, and Enns CA. The hereditary hemochromatosis protein, HFE, lowers intracellular iron levels independently of transferrin receptor 1 in TRVb cells. Blood: 15: 2564-2570, 2004.
    • (2004) Blood , vol.15 , pp. 2564-2570
    • Carlson, H.1    Zhang, A.S.2    Fleming, W.H.3    Enns, C.A.4
  • 7
    • 0032866573 scopus 로고    scopus 로고
    • Overexpression of the hereditary hemochromatosis protein, HFE, in HeLa cells induces an iron-deficient phenotype
    • Corsi B, Levi S, Cozzi A, Corti A, Altimare D, Albertini A, and Arosio P. Overexpression of the hereditary hemochromatosis protein, HFE, in HeLa cells induces an iron-deficient phenotype. FEBS Lett 460: 149-152, 1999.
    • (1999) FEBS Lett , vol.460 , pp. 149-152
    • Corsi, B.1    Levi, S.2    Cozzi, A.3    Corti, A.4    Altimare, D.5    Albertini, A.6    Arosio, P.7
  • 8
    • 2942537827 scopus 로고    scopus 로고
    • Expression of the hereditary hemochromatosis protein HFE increases ferritin levels by inhibiting iron export in HT29 cells
    • Davies PS and Enns CA. Expression of the hereditary hemochromatosis protein HFE increases ferritin levels by inhibiting iron export in HT29 cells. J Biol Chem 279: 25085-25092, 2004.
    • (2004) J Biol Chem , vol.279 , pp. 25085-25092
    • Davies, P.S.1    Enns, C.A.2
  • 15
    • 0037962795 scopus 로고    scopus 로고
    • The orchestration of body iron intake: How and where do enterocytes receive their cues?
    • Frazer DM and Anderson GJ. The orchestration of body iron intake: how and where do enterocytes receive their cues? Blood Cells Mol Dis 30: 288-297, 2003.
    • (2003) Blood Cells Mol Dis , vol.30 , pp. 288-297
    • Frazer, D.M.1    Anderson, G.J.2
  • 18
    • 33644862202 scopus 로고    scopus 로고
    • Iron Imports. IV. Hepcidin and regulation of body iron metabolism
    • 16a. Ganz T and Nemeth E. Iron Imports. IV. Hepcidin and regulation of body iron metabolism. Am J Physiol Gastrointest Liver Physiol 290: G199-G203, 2006.
    • (2006) Am J Physiol Gastrointest Liver Physiol , vol.290
    • Ganz, T.1    Nemeth, E.2
  • 19
    • 2942554825 scopus 로고    scopus 로고
    • HFE and transferrin directly compete for transferrin receptor in solution and at the cell surface
    • Giannetti AM and Bjorkman PJ. HFE and transferrin directly compete for transferrin receptor in solution and at the cell surface. J Biol Chem 279: 25866-25875, 2004.
    • (2004) J Biol Chem , vol.279 , pp. 25866-25875
    • Giannetti, A.M.1    Bjorkman, P.J.2
  • 20
    • 2442657217 scopus 로고    scopus 로고
    • Mechanism for multiple ligand recognition by the human transferrin receptor
    • Giannetti AM, Snow PM, Zak O, and Bjorkman PJ. Mechanism for multiple ligand recognition by the human transferrin receptor. PLoS Biol 1: E51, 2003.
    • (2003) PLoS Biol , vol.1
    • Giannetti, A.M.1    Snow, P.M.2    Zak, O.3    Bjorkman, P.J.4
  • 21
    • 0032555601 scopus 로고    scopus 로고
    • Co-trafficking of HFE, a nonclassical major histocompatibility complex class I protein, with the transferrin receptor implies a role in intracellular iron regulation
    • Gross CN, Irrinki A, Feder JN, and Enns CA. Co-trafficking of HFE, a nonclassical major histocompatibility complex class I protein, with the transferrin receptor implies a role in intracellular iron regulation. J Biol Chem 273: 22068-74, 1998.
    • (1998) J Biol Chem , vol.273 , pp. 22068-22074
    • Gross, C.N.1    Irrinki, A.2    Feder, J.N.3    Enns, C.A.4
  • 22
    • 0032924878 scopus 로고    scopus 로고
    • Reciprocal regulation of HFE and Nramp2 gene expression by iron in human intestinal cells
    • Han O, Fleet JC, and Wood RJ. Reciprocal regulation of HFE and Nramp2 gene expression by iron in human intestinal cells. J Nutr 129: 98-104, 1999.
    • (1999) J Nutr , vol.129 , pp. 98-104
    • Han, O.1    Fleet, J.C.2    Wood, R.J.3
  • 24
  • 25
    • 3042745199 scopus 로고    scopus 로고
    • Duodenal HFE expression and hepcidin levels determine body iron homeostasis: Modulation by genetic diversity and dietary iron availability
    • Ludwiczek S, Theurl I, Artner-Dworzak E, Chorney M, and Weiss G. Duodenal HFE expression and hepcidin levels determine body iron homeostasis: modulation by genetic diversity and dietary iron availability. J Mol Med 82: 373-382, 2004.
    • (2004) J Mol Med , vol.82 , pp. 373-382
    • Ludwiczek, S.1    Theurl, I.2    Artner-Dworzak, E.3    Chorney, M.4    Weiss, G.5
  • 26
    • 24344468431 scopus 로고    scopus 로고
    • Contribution of Hfe expression in macrophages to the regulation of hepatic hepcidin levels and iron loading
    • Makui H, Soares RJ, Jiang W, Constante M, and Santos MM. Contribution of Hfe expression in macrophages to the regulation of hepatic hepcidin levels and iron loading. Blood 106: 2189-2195, 2005.
    • (2005) Blood , vol.106 , pp. 2189-2195
    • Makui, H.1    Soares, R.J.2    Jiang, W.3    Constante, M.4    Santos, M.M.5
  • 27
    • 10044241545 scopus 로고    scopus 로고
    • Transcriptional regulation of the human HFE gene indicates high liver expression and erythropoiesis coregulation
    • Mura C, Le Gac G, Jacolot S, and Ferec C. Transcriptional regulation of the human HFE gene indicates high liver expression and erythropoiesis coregulation. FASEB J 18: 1922-1924, 2004.
    • (2004) FASEB J , vol.18 , pp. 1922-1924
    • Mura, C.1    Le Gac, G.2    Jacolot, S.3    Ferec, C.4
  • 30
    • 0031002910 scopus 로고    scopus 로고
    • Immunohistochemistry of HLA-H, the protein defective in patients with hereditary hemochromatosis, reveals unique pattern of expression in gastrointestinal tract
    • Parkkila S, Waheed A, Britton RS, Feder JN, Tsuchihashi Z, Schatzman RC, Bacon BR, and Sly WS. Immunohistochemistry of HLA-H, the protein defective in patients with hereditary hemochromatosis, reveals unique pattern of expression in gastrointestinal tract. Proc Natl Acad Sci USA 94: 2534-2539, 1997.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 2534-2539
    • Parkkila, S.1    Waheed, A.2    Britton, R.S.3    Feder, J.N.4    Tsuchihashi, Z.5    Schatzman, R.C.6    Bacon, B.R.7    Sly, W.S.8
  • 31
    • 0033605595 scopus 로고    scopus 로고
    • The hereditary hemochromatosis protein, HFE, specifically regulates transferrin-mediated iron uptake in HeLa cells
    • Roy CN, Penny DM, Feder JN, and Enns CA. The hereditary hemochromatosis protein, HFE, specifically regulates transferrin-mediated iron uptake in HeLa cells. J Biol Chem 274: 9022-9028, 1999.
    • (1999) J Biol Chem , vol.274 , pp. 9022-9028
    • Roy, C.N.1    Penny, D.M.2    Feder, J.N.3    Enns, C.A.4
  • 32
    • 0032576567 scopus 로고    scopus 로고
    • Cloning, sequencing and characterization of the rat hereditary hemochromatosis promoter: Comparison of the human, mouse and rat HFE promoter regions
    • Sanchez M, Queralt R, Bruguera M, Rodes J, and Oliva R. Cloning, sequencing and characterization of the rat hereditary hemochromatosis promoter: comparison of the human, mouse and rat HFE promoter regions. Gene 225: 77-87, 1998.
    • (1998) Gene , vol.225 , pp. 77-87
    • Sanchez, M.1    Queralt, R.2    Bruguera, M.3    Rodes, J.4    Oliva, R.5
  • 33
    • 0029809511 scopus 로고    scopus 로고
    • Defective iron homeostasis in beta 2-microglobulin knockout mice recapitulates hereditary hemochromatosis in man
    • Santos M, Schilham MW, Rademakers LH, Marx JJ, de Sousa M, and Clevers H. Defective iron homeostasis in beta 2-microglobulin knockout mice recapitulates hereditary hemochromatosis in man. J Exp Med 184: 1975-1985, 1996.
    • (1996) J Exp Med , vol.184 , pp. 1975-1985
    • Santos, M.1    Schilham, M.W.2    Rademakers, L.H.3    Marx, J.J.4    De Sousa, M.5    Clevers, H.6
  • 34
    • 24344434227 scopus 로고    scopus 로고
    • Pathways for the regulation of body iron homeostasis in response to experimental iron overload
    • Theurl I, Ludwiczek S, Eller P, Seifert M, Artner E, Brunner P, and Weiss G. Pathways for the regulation of body iron homeostasis in response to experimental iron overload. J Hepatol 43: 711-719, 2005.
    • (2005) J Hepatol , vol.43 , pp. 711-719
    • Theurl, I.1    Ludwiczek, S.2    Eller, P.3    Seifert, M.4    Artner, E.5    Brunner, P.6    Weiss, G.7
  • 36
    • 0037117603 scopus 로고    scopus 로고
    • Iron uptake from plasma transferrin by the duodenum is impaired in the Hfe knockout mouse
    • Trinder D, Olynyk JK, Sly WS, and Morgan EH. Iron uptake from plasma transferrin by the duodenum is impaired in the Hfe knockout mouse. Proc Natl Acad Sci USA 99: 5622-5626, 2002.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 5622-5626
    • Trinder, D.1    Olynyk, J.K.2    Sly, W.S.3    Morgan, E.H.4
  • 38
    • 0030732164 scopus 로고    scopus 로고
    • Hereditary hemochromatosis: Effects of C282Y and H63D mutations on association with beta2-microglobulin, intracellular processing, and cell surface expression of the HFE protein in COS-7 cells
    • Waheed A, Parkkila S, Zhou XY, Tomatsu S, Tsuchihashi Z, Feder JN, Schatzman RC, Britton RS, Bacon BR, and Sly WS. Hereditary hemochromatosis: effects of C282Y and H63D mutations on association with beta2-microglobulin, intracellular processing, and cell surface expression of the HFE protein in COS-7 cells. Proc Natl Acad Sci USA 94: 12384-12389, 1997.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 12384-12389
    • Waheed, A.1    Parkkila, S.2    Zhou, X.Y.3    Tomatsu, S.4    Tsuchihashi, Z.5    Feder, J.N.6    Schatzman, R.C.7    Britton, R.S.8    Bacon, B.R.9    Sly, W.S.10
  • 39
    • 0037444795 scopus 로고    scopus 로고
    • The haemochromatosis protein HFE induces an apparent iron-deficient phenotype in H1299 cells that is not corrected by co-expression of beta 2-microglobulin
    • Wang J, Chen G, and Pantopoulos K. The haemochromatosis protein HFE induces an apparent iron-deficient phenotype in H1299 cells that is not corrected by co-expression of beta 2-microglobulin. Biochem J 370: 891-899, 2003.
    • (2003) Biochem J , vol.370 , pp. 891-899
    • Wang, J.1    Chen, G.2    Pantopoulos, K.3
  • 40
    • 33645835497 scopus 로고    scopus 로고
    • Haemochromatosis protein is expressed on the terminal web of enterocytes in proximal small intestine of the rat
    • West AR, Thomas C, Sadlier J, and Oates PS. Haemochromatosis protein is expressed on the terminal web of enterocytes in proximal small intestine of the rat. Histochem Cell Biol 1-10, 2005.
    • (2005) Histochem Cell Biol , pp. 1-10
    • West, A.R.1    Thomas, C.2    Sadlier, J.3    Oates, P.S.4
  • 41
    • 0842263988 scopus 로고    scopus 로고
    • Localization of iron metabolism-related mRNAs in rat liver indicate that HFE is expressed predominantly in hepatocytes
    • Zhang AS, Xiong S, Tsukamoto H, and Enns CA. Localization of iron metabolism-related mRNAs in rat liver indicate that HFE is expressed predominantly in hepatocytes. Blood 103: 1509-1514, 2004.
    • (2004) Blood , vol.103 , pp. 1509-1514
    • Zhang, A.S.1    Xiong, S.2    Tsukamoto, H.3    Enns, C.A.4


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