The whys and wherefores of phosphate removal

EMBO Reports

Volumn 7, Issue 3, 2006, Pages 263-268

  Bennett, Daimark ^a   Matthews, R James ^b   Sathish, Jean G ^c  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b CARDIFF UNIVERSITY   (United Kingdom)

^c UNIVERSITY OF LIVERPOOL   (United Kingdom)

Author keywords

Immunology; Protein phosphatases; Regulation; Serine threonine phosphorylation; Tyrosine phosphorylation

Indexed keywords

CANTHARIDIN; CISPLATIN; CISPLATIN DERIVATIVE; FOSTRIECIN; IMATINIB; PHOSPHATE; PHOSPHOPROTEIN PHOSPHATASE; PROTEIN TYROSINE PHOSPHATASE INHIBITOR; PROTEIN TYROSINE PHOSPHATASE SHP 2; REACTIVE OXYGEN METABOLITE; SCAFFOLD PROTEIN; SERINE; THREONINE; TYROSINE DERIVATIVE;

ANTIGEN PRESENTING CELL; ANTINEOPLASTIC ACTIVITY; CATALYSIS; CELL DIFFERENTIATION; CELLULAR DISTRIBUTION; CELLULAR IMMUNITY; CIRCADIAN RHYTHM; CONFERENCE PAPER; DNA DAMAGE; DRUG HYPERSENSITIVITY; DRUG SYNTHESIS; ENZYME ACTIVITY; GENE MUTATION; HUMAN; LONG TERM POTENTIATION; OBESITY; OXIDATION; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DEPHOSPHORYLATION; PROTEIN DETERMINATION; PROTEIN LOCALIZATION; PROTEIN METHYLATION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN PURIFICATION; PROTEIN STABILITY; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; T LYMPHOCYTE;

ANIMALS; CONGRESSES; DRUG DESIGN; HUMANS; IMMUNE SYSTEM; MODELS, MOLECULAR; PHOSPHATES; PHOSPHORIC MONOESTER HYDROLASES; PROTEIN CONFORMATION;

EID: 33645788355     PISSN: 1469221X     EISSN: 14693178     Source Type: Journal    
DOI: 10.1038/sj.embor.7400644     Document Type: Conference Paper

References (24)

1. Alonso A, Sasin J, Bottini N, Friedberg I, Osterman A, Godzik A, Hunter T, Dixon J, Mustelin T (2004) Protein tyrosine phosphatases in the human genome. Cell 117: 699-711
2. Andersen JN, Jansen PG, Echwald SM, Mortensen OH, Fukada T, Del Vecchio R, Tonks NK, Moller NP (2004) A genomic perspective on protein tyrosine phosphatases: Gene structure, pseudogenes, and genetic disease linkage. FASEB J 18: 8-30
3. Araki T et al (2004) Mouse model of Noonan syndrome reveals cell type- and gene dosage-dependent effects of Ptpn11 mutation. Nat Med 10: 849-857
4. Barford D (1996) Molecular mechanisms of the protein serine/threonine phosphatases. Trends Biochem Sci 21: 407-412
5. Bottini N et al (2004) A functional variant of lymphoid tyrosine phosphatase is associated with type I diabetes. Nat Genet 36: 337-338
6. Carr AN et al (2002). Type 1 phosphatase, a negative regulator of cardiac function. Mol Cell Biol 22: 4124-4135
7. Cohen PT, Philp A, Vazquez-Martin C (2005) Protein phosphatase 4 - from obscurity to vital functions. FEBS Lett 579: 3278-3286
8. Eide EJ, Kang H, Crapo S, Gallego M, Virshup DM (2005) Casein kinase I in the mammalian circadian clock. Methods Enzymol 393: 408-418
9. Fellner T, Lackner DH, Hombauer H, Piribauer P, Mudrak I, Zaragoza K, Juno C, Ogris E (2003) A novel and essential mechanism determining specificity and activity of protein phosphatase 2A (PP2A) in vivo. Genes Dev 17: 2138-2150
10. Gingras AC, Caballero M, Zarske M, Sanchez A, Hazbun TR, Fields S, Sonenberg N, Hafen E, Raught B, Aebersold R (2005) A novel, evolutionarily conserved protein phosphatase complex involved in cisplatin sensitivity. Mol Cell Proteomics 4: 1725-1740
11. Gohla A, Birkenfeld J, Bokoch GM (2005) Chronophin, a novel HAD-type serine protein phosphatase, regulates cofilin-dependent actin dynamics. Nat Cell Biol 7: 21-29
12. Huynh H et al (2004) Control of vesicle fusion by a tyrosine phosphatase. Nat Cell Biol 6: 831-839
13. Keilhack H, David FS, McGregor M, Cantley LC, Neel BG (2005) Diverse biochemical properties of Shp2 mutants: Implications for disease phenotypes. J Biol Chem 280: 30984-30993
14. Kirchhefer U et al (2005) Enhanced cardiac function in mice overexpressing protein phosphatase inhibitor-2. Cardiovasc Res 68: 98-108
15. Lesage B, Beullens M, Nuytten M, Van Eynde A, Keppens S, Himpens B, Bollen M (2004) Interactor-mediated nuclear translocation and retention of protein phosphatase-1. J Biol Chem 279: 55978-55984
16. Longin S et al (2004) An inactive protein phosphatase 2A population is associated with methylesterase and can be re-activated by the phosphotyrosyl phosphatase activator. Biochem J 380: 111-119
17. Meng TC, Buckley DA, Galic S, Tiganis T, Tonks NK (2004) Regulation of insulin signaling through reversible oxidation of the protein-tyrosine phosphatases TC45 and PTP1B. J Biol Chem 279: 37716-37725
18. Mohi MG et al (2005) Prognostic, therapeutic, and mechanistic implications of a mouse model of leukemia evoked by Shp2 (PTPN11) mutations. Cancer Cell 7: 179-191
19. Paling NR, Welham MJ (2005) Tyrosine phosphatase SHP-1 acts at different stages of development to regulate hematopoiesis. Blood 105: 4290-4297
20. Salmeen A, Andersen JN, Myers MP, Meng TC, Hinks JA, Tonks NK, Barford D (2003) Redox regulation of protein tyrosine phosphatase 1B involves a sulphenyl-amide intermediate. Nature 423: 769-773
21. Terry-Lorenzo RT, Roadcap DW, Otsuka T, Blanpied TA, Zamorano PL, Garner CC, Shenolikar S, Ehlers MD (2005) Neurabin/protein phosphatase-1 complex regulates dendritic spine morphogenesis and maturation. Mol Biol Cell 16: 2349-2362
22. Vereshchagina N, Bennett D, Szoor B, Kirchner J, Gross S, Vissi E, White-Cooper H, Alphey L (2004) the essential role of PP1β in Drosophila is to regulate nonmuscle myosin. Mol Biol Cell 15: 4395-4405
23. Wang Z et al (2004) Mutational analysis of the tyrosine phosphatome in colorectal cancers. Science 304: 1164-1166
24. Yang J, Roe SM, Cliff MJ, Williams MA, Ladbury JE, Cohen PT, Barford D (2005) Molecular basis for TPR domain-mediated regulation of protein phosphatase 5. EMBO J 24: 1-10