Ohanin, a novel protein from king cobra venom: Its cDNA and genomic organization

Gene

Volumn 371, Issue 2, 2006, Pages 246-256

  Pung, Yuh Fen ^a   Kumar, Sanjeed Vijaya ^a   Rajagopalan, Nandhakishore ^a   Fry, Bryan G ^a,b   Kumar, Prakash P ^a   Kini, R Manjunatha ^a,c  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^b UNIVERSITY OF MELBOURNE   (Australia)

^c VIRGINIA COMMONWEALTH UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Alternative splicing; B30.2 like domain; PRY SPRY domains; Vespryns

Indexed keywords

COMPLEMENTARY DNA; MESSENGER RNA; OHANIN; SNAKE VENOM; UNCLASSIFIED DRUG; VESPRYNS;

5' UNTRANSLATED REGION; AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; DNA SEQUENCE; EXON; GENE SEQUENCE; GENETIC CODE; GENETIC ORGANIZATION; INTRON; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DOMAIN; RNA SPLICING; SNAKE; SOUTHERN BLOTTING;

AMINO ACID SEQUENCE; ANIMALS; BLOTTING, SOUTHERN; CLONING, MOLECULAR; COBRA VENOMS; DNA, COMPLEMENTARY; GENOME; MOLECULAR SEQUENCE DATA; SEQUENCE HOMOLOGY, AMINO ACID;

OPHIOPHAGUS HANNAH;

EID: 33645780230     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.gene.2005.12.002     Document Type: Article

References (42)

1. Altschul S.F., et al. Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. Nucleic Acids Res. 25 (1997) 3389-3402
2. Ast G. How did alternative splicing evolve?. Nat. Rev. Genet. 5 (2004) 773-782
3. Bendtsen J.D., Nielsen H., Von Heijne G., and Brunak S. Improved prediction of signal peptides: signalP 3.0. J. Mol. Biol. 340 (2004) 783-795
4. Breathnach R., and Chambon P. Organization and expression of eukaryotic split genes coding for proteins. Ann. Rev. Biochem. 50 (1981) 349-383
5. Brett D., et al. EST comparison indicates 38% of human mRNAs contain possible alternative splice forms. FEBS Lett. 474 (2000) 83-86
6. Croft L., Schandorff S., Clark F., Burrage K., Arctander P., and Mattick J.S. ISIS, the intron information system, reveals the high frequency of alternative splicing in the human genome. Nat. Genet. 24 (2000) 340-341
7. Fry B.G. From genome to "venome": molecular origin and evolution of the snake venom proteome inferred from phylogenetic analysis of toxin sequences and related body proteins. Genome Res. 15 (2005) 403-420
8. Gassama-Diagne A., et al. Enterophilins, a new family of leucine zipper proteins bearing a B30.2 domain and associated with enterocyte differentiation. J. Biol. Chem. 276 (2001) 18352-18360
9. Ghadessy F.J., et al. Stonustoxin is a novel lethal factor from stonefish (Synanceja horrida) venom: cDNA cloning and characterization. J. Biol. Chem. 271 (1996) 25575-25581
10. Henry J., et al. Cloning, structural analysis, and mapping of the B30 and B7 multigenic families to the major histocompatibility complex (MHC) and other chromosomal regions. Immunogenetics 46 (1997) 383-395
11. Henry J., Ribouchon M.T., Offer C., and Pontarotti P. B30.2-like domain proteins: a growing family. Biochem. Biophys. Res. Commun. 235 (1997) 162-165
12. Henry J., Mather I.H., McDermott M.F., and Pontarotti P. B30.2-like domain proteins: update and new insights into a rapidly expanding family of proteins. Mol. Biol. Evol. 15 (1998) 1696-1705
13. Hilton D.J., et al. Twenty proteins containing a C-terminal SOCS box form five structural classes. Proc. Natl. Acad. Sci. U. S. A. 95 (1998) 114-119
14. Kan Z., Rouchka E.C., Gish W.R., and States D.J. Gene structure prediction and alternative splicing analysis using genomically aligned ESTs. Genome Res. 11 (2001) 889-900
15. Karlsson E. Chemistry of protein toxins in snake venoms. In: Lee C.Y. (Ed). Snake Venoms (1979), Springer-Verlag, NY 159-212
16. Kini R.M. Molecular moulds with multiple missions: functional sites in three-finger toxins. Clin. Exp. Pharmacol. Physiol. 29 (2002) 815-822
17. Kozak M. Possible role of flanking nucleotides in recognition of the AUG initiator codon by eukaryotic ribosomes. Nucleic Acids Res. 9 (1981) 5233-5252
18. Kozak M. Compilation and analysis of sequences upstream from the translational start site in eukaryotic mRNAs. Nucleic Acids Res. 12 (1984) 857-872
19. Kozak M. An analysis of 5′-noncoding sequences from 699 vertebrate messenger RNAs. Nucleic Acids Res. 15 (1987) 8125-8148
20. Kozak M. At least six nucleotides preceding the AUG initiator codon enhance translation in mammalian cells. J. Mol. Biol. 196 (1987) 947-950
21. Kozak M. The scanning model for translation: an update. J. Cell Biol. 108 (1989) 229-241
22. Li S., et al. Proteomic characterization of two snake venoms: Naja naja atra and Agkistrodon halys. Biochem. J. 15 (2004) 119-127
23. Marchler-Bauer A., et al. CDD: a curated Entrez database of conserved domain alignments. Nucleic Acids Res. 31 (2003) 383-387
24. Meyer M., Gaudieri S., Rhodes D.A., and Trowsdale J. Cluster of TRIM genes in the human MHC class I region sharing the B30.2 domain. Tissue Antigens 61 (2003) 63-71
25. Mironov A.A., Fickett J.W., and Gelfand M.S. Frequent alternative splicing of human genes. Genome Res. 9 (1999) 1288-1293
26. Mochca-Morales J., Martin B.M., and Possani L.D. Isolation and characterization of helothermine, a novel toxin from Heloderma horridum horridum (Mexican beaded lizard) venom. Toxicon 28 (1990) 299-309
27. Ogg S.L., Komaragiri M.V., and Mather I.H. Structural organization and mammary-specific expression of the butyrophilin gene. Mamm. Genome 7 (1996) 900-905
28. Okazaki Y., et al. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature 420 (2002) 563-573
29. Orimo A., et al. Molecular cloning of testis-abundant finger protein/ring finger protein 23 (RNF23), a novel RING-B box-coiled coil-B30.2 protein on the class I region of the human MHC. Biochem. Biophys. Res. Commun. 276 (2000) 45-51
30. Paetzel M., Dalbey R.E., and Strynadka N.C.J. Crystal structure of a bacterial signal peptidase in complex with a beta-lactam inhibitor. Nature 396 (1998) 186-190
31. Proudfoot N.J., and Brownlee G.G. 3′ Non-coding region sequences in eukaryotic messenger RNA. Nature 263 (1976) 211-214
32. Pung Y.F., Wong P.T.H., Kumar P.P., Hodgson W.C., and Kini R.M. Ohanin, a novel protein from king cobra venom induces hypolocomotion and hyperalgesia in mice. J. Biol. Chem. 280 (2005) 13137-13147
33. Rhodes D.A., Stammers M., Malcherek G., Beck S., and Trowsdale J. The cluster of BTN genes in the extended major histocompatibility complex. Genomics 71 (2001) 351-362
34. Sanger F., Nicklen S., and Coulson A.R. DNA sequencing with chain-terminating inhibitors. Proc. Natl. Acad. Sci. U. S. A. 74 (1977) 5463-5467
35. Sawyer S.L., Wu L., Emerman M., and Malik H.S. Positive selection of primate TRIM5 alpha identifies a critical species-specific retroviral restriction domain. Proc. Natl. Acad. Sci. U. S. A. 102 (2005) 2832-2837
36. Smith L.A. Cloning, characterization and expression of animal toxin genes for vaccine development. J. Toxicol., Toxin Rev. 9 (1990) 243-283
37. Torres A.M., Wong H.Y., Desai M., Moochhala S., Kuchel P.W., and Kini R.M. Identification of a novel family of proteins in snake venoms: purification and structural characterization of nawaprin from Naja nigricollis snake venom. J. Biol. Chem. 278 (2003) 40097-40104
38. Vernet C., et al. Evolutionary study of multigenic families mapping close to the human MHC class I region. J. Mol. Evol. 37 (1993) 600-612
39. Von Heijne G. A new method for predicting signal sequence cleavage site. Nucleic Acids Res. 14 (1986) 4683-4690
40. Von Heijne G. Life and death of a signal peptide. Nature 396 (1998) 111-112
41. Yamazaki Y., Hyodo F., and Morita T. Wide distribution of cysteine-rich secretory proteins in snake venoms: isolation and cloning of novel snake venom cysteine-rich secretory proteins. Arch. Biochem. Biophys. 412 (2003) 133-141
42. Yao S., et al. Backbone 1H, 13C and 15N assignments of the 25 kDa SPRY domain-containing SOCS box protein 2 (SSB-2). J. Biomol. NMR 31 (2005) 69-70