메뉴 건너뛰기




Volumn 61, Issue 4, 2006, Pages 301-305

Low molecular weight quaternised chitosan (II): In vitro assessment of absorption enhancing properties

Author keywords

[No Author keywords available]

Indexed keywords

CHITOSAN; PENETRATION ENHANCING AGENT; POLYMER;

EID: 33645773203     PISSN: 00317144     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (11)

References (28)
  • 1
    • 0343150936 scopus 로고    scopus 로고
    • The potential of mucoadhesive polymers in enhancing intestinal peptide drug absorption. III: Effects of chitosan-glutamate and carbomer on epithelial tight junctions in vitro
    • Borchard G, Lueßen HL, De Boer AG, Verhoef JC, Lehr C-M, Junginger HE (1996) The potential of mucoadhesive polymers in enhancing intestinal peptide drug absorption. III: effects of chitosan-glutamate and carbomer on epithelial tight junctions in vitro. J Control Release 39: 131-138.
    • (1996) J Control Release , vol.39 , pp. 131-138
    • Borchard, G.1    Lueßen, H.L.2    De Boer, A.G.3    Verhoef, J.C.4    Lehr, C.-M.5    Junginger, H.E.6
  • 4
    • 0021840433 scopus 로고
    • Correlation between nasal ciliary beat frequency and mucus transport rate in volunteers
    • Duchateau GSMJE, Graamans K, Zuidema J, Merkus FWHM (1985) Correlation between nasal ciliary beat frequency and mucus transport rate in volunteers. Laryngoscope 95: 854-860.
    • (1985) Laryngoscope , vol.95 , pp. 854-860
    • Duchateau, G.S.M.J.E.1    Graamans, K.2    Zuidema, J.3    Merkus, F.W.H.M.4
  • 6
    • 0032054501 scopus 로고    scopus 로고
    • Innovative strategies for the oral delivery of drugs and peptides
    • Fasano A (1998) Innovative strategies for the oral delivery of drugs and peptides. Trends Biotechnol 16:152-57
    • (1998) Trends Biotechnol , vol.16 , pp. 152-157
    • Fasano, A.1
  • 7
    • 0031714427 scopus 로고    scopus 로고
    • Chitosan: A unique polysaccharide for drug delivery
    • Felt O, Bun P, Gurny R (1998) Chitosan: a unique polysaccharide for drug delivery. Drug Devel Ind Pharm 24: 979-993.
    • (1998) Drug Devel Ind Pharm , vol.24 , pp. 979-993
    • Felt, O.1    Bun, P.2    Gurny, R.3
  • 9
    • 0010634731 scopus 로고
    • Introduction: Principles of sterile technique and cell propagation
    • Freshney RI (ed.). Washington
    • Freshney RI (1986) Introduction: principles of sterile technique and cell propagation. In: Freshney RI (ed.) Animal cell culture: a practical approach, Washington, p. 1-11.
    • (1986) Animal Cell Culture: A Practical Approach , pp. 1-11
    • Freshney, R.I.1
  • 10
    • 0034957378 scopus 로고    scopus 로고
    • Effect of type of base and number or reaction steps on the degree of quaternization and molecular weight of N-trimethyl chitosan chloride
    • Hamman JH, Kotzé AF (2001) Effect of type of base and number or reaction steps on the degree of quaternization and molecular weight of N-trimethyl chitosan chloride. Drug Devel Ind Pharm 27: 373-380.
    • (2001) Drug Devel Ind Pharm , vol.27 , pp. 373-380
    • Hamman, J.H.1    Kotzé, A.F.2
  • 11
    • 0007677031 scopus 로고
    • The influence of drugs on ciliary movement
    • Hermens WAJJ, Merkus FWHM (1987) The influence of drugs on ciliary movement. Pharm Res 4: 445-449.
    • (1987) Pharm Res , vol.4 , pp. 445-449
    • Hermens, W.A.J.J.1    Merkus, F.W.H.M.2
  • 12
    • 0031783879 scopus 로고    scopus 로고
    • Chitosan and its use as a pharmaceutical excipient
    • Illum L (1998) Chitosan and its use as a pharmaceutical excipient. Pharm Res 15: 1326-1331.
    • (1998) Pharm Res , vol.15 , pp. 1326-1331
    • Illum, L.1
  • 15
    • 0033007333 scopus 로고    scopus 로고
    • Enhancement of paracellular drug transport with highly quaternized N-trimethyl chitosan chloride in neutral environments: In vitro evaluation in intestinal epithelial cells (Caco-2)
    • Kotzé AF, Thanou MM, Lueßen HL, De Boer AG, Verhoef JC, Junginger HE (1999b) Enhancement of paracellular drug transport with highly quaternized N-trimethyl chitosan chloride in neutral environments: In vitro evaluation in intestinal epithelial cells (Caco-2). J Pharm Sci 88: 253-257.
    • (1999) J Pharm Sci , vol.88 , pp. 253-257
    • Kotzé, A.F.1    Thanou, M.M.2    Lueßen, H.L.3    De Boer, A.G.4    Verhoef, J.C.5    Junginger, H.E.6
  • 16
    • 0033039070 scopus 로고    scopus 로고
    • Effect of the degree of quaternization of N-trimethyl chitosan chloride on the permeability of intestinal epithelial cells (Caco-2)
    • Kotzé AF, Thanou MM, Lueßen HL, De Boer AG, Verhoef JC, Junginger HE (1999c) Effect of the degree of quaternization of N-trimethyl chitosan chloride on the permeability of intestinal epithelial cells (Caco-2). Eur J Pharm Biopharm 47: 269-274.
    • (1999) Eur J Pharm Biopharm , vol.47 , pp. 269-274
    • Kotzé, A.F.1    Thanou, M.M.2    Lueßen, H.L.3    De Boer, A.G.4    Verhoef, J.C.5    Junginger, H.E.6
  • 17
    • 33645758758 scopus 로고    scopus 로고
    • Mucoadhesive and absorption enhancing properties of N-trimethyl chitosan chloride
    • Muzzarelli RAA, Muzzarelli C (Eds.). Italy
    • Kotzé AF, Hamman JH, Snyman D, Jonker C, Stander M (2002) Mucoadhesive and absorption enhancing properties of N-trimethyl chitosan chloride. In: Muzzarelli RAA, Muzzarelli C (Eds.) Chitosan in Pharmacy and Chemistry, Italy: pp. 31-40.
    • (2002) Chitosan in Pharmacy and Chemistry , pp. 31-40
    • Kotzé, A.F.1    Hamman, J.H.2    Snyman, D.3    Jonker, C.4    Stander, M.5
  • 18
    • 0003062536 scopus 로고
    • Changing needs in drug delivery in the era of peptide and protein drug absorption
    • Lee VHD (ed.). New York
    • Lee VHL (1991) Changing needs in drug delivery in the era of peptide and protein drug absorption. In: Lee VHD (ed.) Peptide and Protein Drag Delivery, New York, pp. 1-56.
    • (1991) Peptide and Protein Drag Delivery , pp. 1-56
    • Lee, V.H.L.1
  • 19
    • 0025878065 scopus 로고
    • Absorption enhancing effect of cyclodextrins on intranasally administered insulin in rats
    • Merkus FWHM, Verhoef J, Romeijn SG, Schipper GM (1991) Absorption enhancing effect of cyclodextrins on intranasally administered insulin in rats. Pharm Res 8: 588-590.
    • (1991) Pharm Res , vol.8 , pp. 588-590
    • Merkus, F.W.H.M.1    Verhoef, J.2    Romeijn, S.G.3    Schipper, G.M.4
  • 20
    • 0028326230 scopus 로고
    • The assessment of nasal mucociliary clearance and the effect of drugs
    • Rusznak C, Devalia DL, Lozewics S, Davies RJ (1994) The assessment of nasal mucociliary clearance and the effect of drugs. Respir Med 88: 89-101.
    • (1994) Respir Med , vol.88 , pp. 89-101
    • Rusznak, C.1    Devalia, D.L.2    Lozewics, S.3    Davies, R.J.4
  • 21
    • 0025851808 scopus 로고
    • The nasal mucociliary clearance: Relevance to nasal drug delivery
    • Schipper NGM, Verhoef JC, Merkus FWHM (1991) The nasal mucociliary clearance: relevance to nasal drug delivery. Pharm Res 8: 807-814.
    • (1991) Pharm Res , vol.8 , pp. 807-814
    • Schipper, N.G.M.1    Verhoef, J.C.2    Merkus, F.W.H.M.3
  • 22
    • 0008590610 scopus 로고    scopus 로고
    • Functional histology of epithelia relevant for drug delivery: Respiratory tract, digestive tract, eye, skin and vagina
    • Mathiowitz E, Chickering DE, Lehr C-M (eds.). New York
    • Schumacher U, Schumacher D (1999) Functional histology of epithelia relevant for drug delivery: respiratory tract, digestive tract, eye, skin and vagina. In: Mathiowitz E, Chickering DE, Lehr C-M (eds.) Bioadhesive drug delivery systems fundamentals, novel approaches and development. New York, pp. 67-83;
    • (1999) Bioadhesive Drug Delivery Systems Fundamentals, Novel Approaches and Development , pp. 67-83
    • Schumacher, U.1    Schumacher, D.2
  • 23
    • 0142229423 scopus 로고    scopus 로고
    • Low molecular weight quaternised chitosan (I): Synthesis and characterisation
    • Snyman D, Govender T, Kotze AF (2003) Low molecular weight quaternised chitosan (I): synthesis and characterisation. Pharmazie 58: 705-708.
    • (2003) Pharmazie , vol.58 , pp. 705-708
    • Snyman, D.1    Govender, T.2    Kotze, A.F.3
  • 24
    • 0032815732 scopus 로고    scopus 로고
    • Effect of N-trimethyl chitosan chloride, a novel absorption enhancer, on Caco-2 intestinal epithelia and the ciliary beat frequency of chicken embryo trachea
    • Thanou MM, Verhoef JC, Romeijn SG, Nagelkerke JF, Merkus FWHM, Junginger HE (1999) Effect of N-trimethyl chitosan chloride, a novel absorption enhancer, on Caco-2 intestinal epithelia and the ciliary beat frequency of chicken embryo trachea. Int J Pharm 185: 73-82.
    • (1999) Int J Pharm , vol.185 , pp. 73-82
    • Thanou, M.M.1    Verhoef, J.C.2    Romeijn, S.G.3    Nagelkerke, J.F.4    Merkus, F.W.H.M.5    Junginger, H.E.6
  • 25
    • 0033960143 scopus 로고    scopus 로고
    • Effect of degree of quaternization of N-trimethyl chitosan chloride for enhanced transport of hydrophilic compounds across intestinal Caco-2 cell monolayers
    • Thanou MM, Kotzé AF, Scharringhausen T, Lueßen HL, De Boer AG, Verhoef JC, Junginger HE (2000) Effect of degree of quaternization of N-trimethyl chitosan chloride for enhanced transport of hydrophilic compounds across intestinal Caco-2 cell monolayers. J Contr Release 64: 15-25.
    • (2000) J Contr Release , vol.64 , pp. 15-25
    • Thanou, M.M.1    Kotzé, A.F.2    Scharringhausen, T.3    Lueßen, H.L.4    De Boer, A.G.5    Verhoef, J.C.6    Junginger, H.E.7
  • 26
    • 0036027454 scopus 로고    scopus 로고
    • Quaternized chitosan oligomers as novel gene delivery vectors in epithelial cell lines
    • Thanou MM, Florea BI, Geldof M, Junginger HE, Borchard G (2002) Quaternized chitosan oligomers as novel gene delivery vectors in epithelial cell lines. Biomaterials 23: 153-159.
    • (2002) Biomaterials , vol.23 , pp. 153-159
    • Thanou, M.M.1    Florea, B.I.2    Geldof, M.3    Junginger, H.E.4    Borchard, G.5
  • 27
    • 0037443713 scopus 로고    scopus 로고
    • Peptide and protein drug delivery to and into tumors: Challenges and solutions
    • Torchilin VP, Lukyanov AN (2003) Peptide and protein drug delivery to and into tumors: challenges and solutions. Drug Discov Today 8: 259-266.
    • (2003) Drug Discov Today , vol.8 , pp. 259-266
    • Torchilin, V.P.1    Lukyanov, A.N.2
  • 28
    • 0019995531 scopus 로고
    • The influence of pH and osmotic pressure upon tracheal ciliary beat frequency as determined with new photo-electric registration device
    • Van de Donk HJM, Zuidema J, Merkus FWHM (1982) The influence of pH and osmotic pressure upon tracheal ciliary beat frequency as determined with new photo-electric registration device. Rhinology 20: 81-87.
    • (1982) Rhinology , vol.20 , pp. 81-87
    • Van De Donk, H.J.M.1    Zuidema, J.2    Merkus, F.W.H.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.