Comparison of G-protein coupled receptor desensitization-related β-arrestin redistribution using confocal and non-confocal imaging

Combinatorial Chemistry and High Throughput Screening

Volumn 9, Issue 1, 2006, Pages 37-47

  Haasen, Dorothea ^a   Wolff, Michael ^a   Valler, Martin J ^a   Heilker, Ralf ^a  

^a BOEHRINGER INGELHEIM PHARMA GMBH AND CO KG   (Germany)

Author keywords

arrestin redistribution; Confocal imaging; High content screening; Subcellular translocation

Indexed keywords

BETA 2 ADRENERGIC RECEPTOR; BETA ARRESTIN; G PROTEIN COUPLED RECEPTOR; GREEN FLUORESCENT PROTEIN;

ANALYTICAL EQUIPMENT; ARTICLE; BINDING AFFINITY; CARBOXY TERMINAL SEQUENCE; CELL STRUCTURE; COMPARATIVE STUDY; CONFOCAL MICROSCOPY; DESENSITIZATION; DEVICE; ENDOSOME; FEASIBILITY STUDY; HUMAN; HUMAN CELL; IMAGE ANALYSIS; IMAGING; MICROTITER PLATE ASSAY; PRIORITY JOURNAL; PROTEIN INTERACTION; RECEPTOR AFFINITY;

ARRESTINS; CELL MEMBRANE; CELLS, CULTURED; CYTOSOL; DOSE-RESPONSE RELATIONSHIP, DRUG; GREEN FLUORESCENT PROTEINS; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; ISOPROTERENOL; MICROSCOPY, CONFOCAL; MICROSCOPY, FLUORESCENCE; MODELS, BIOLOGICAL; PROPRANOLOL; RECEPTORS, ADRENERGIC, BETA-2; RECEPTORS, ODORANT; SENSITIVITY AND SPECIFICITY; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 33645751458     PISSN: 13862073     EISSN: None     Source Type: Journal    
DOI: 10.2174/138620706775213921     Document Type: Article

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