Yeast Trf5p is a nuclear poly(A) polymerase

EMBO Reports

Volumn 7, Issue 2, 2006, Pages 205-211

  Houseley, Jonathan ^a   Tollervey, David ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

Polyadenylation; RNA degradation; RNA surveillance; TRAMP complex; Yeast

Indexed keywords

FUNGAL PROTEIN; POLYNUCLEOTIDE ADENYLYLTRANSFERASE; RIBOSOME RNA; RNA HELICASE; DNA DIRECTED RNA POLYMERASE; FUNGAL RNA; MESSENGER RNA; SACCHAROMYCES CEREVISIAE PROTEIN; TRF5 PROTEIN, S CEREVISIAE;

AMINO ACID SEQUENCE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME DEGRADATION; ENZYME LOCALIZATION; ENZYME PURIFICATION; FUNGAL STRAIN; GENE OVEREXPRESSION; IN VITRO STUDY; NONHUMAN; POINT MUTATION; POLYADENYLATION; PREDICTION; PRIORITY JOURNAL; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY; TANDEM REPEAT; YEAST CELL; CELL NUCLEUS; CHEMISTRY; ENZYMOLOGY; FUNGAL GENE; GENETICS; GROWTH, DEVELOPMENT AND AGING; METABOLISM; MOLECULAR GENETICS; SACCHAROMYCES CEREVISIAE;

AMINO ACID SEQUENCE; CELL NUCLEUS; DNA-DIRECTED RNA POLYMERASES; GENES, FUNGAL; MOLECULAR SEQUENCE DATA; POINT MUTATION; POLYADENYLATION; POLYNUCLEOTIDE ADENYLYLTRANSFERASE; RNA HELICASES; RNA, FUNGAL; RNA, MESSENGER; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS;

EID: 33645739358     PISSN: 1469221X     EISSN: 14693178     Source Type: Journal    
DOI: 10.1038/sj.embor.7400612     Document Type: Article

References (20)

1. Allmang C, Kufel J, Chanfreau G, Mitchell P, Petfalski E, Tollervey D (1999) Functions of the exosome in rRNA, snoRNA and snRNA synthesis. EMBO J 18: 5399-5410
2. Bousquet-Antonelli C, Presutti C, Tollervey D (2000) Identification of a regulated pathway for nuclear pre-mRNA turnover. Cell 102: 765-775
3. Castano IB, Heath-Pagliuso S, Sadoff BU, Fitzhugh DJ, Christman MF (1996) A novel family of TRF (DNA topoisomerase I-related function) genes required for proper nuclear segregation. Nucleic Acids Res 24: 2404-2410
4. de la Cruz J, Kressler D, Tollervey D, Linder P (1998) Dob1p (Mtr4p) is a putative ATP-dependent RNA helicase required for the 3′ end formation of 5.8S rRNA in Saccharomyces cerevisiae. EMBO J 17: 1128-1140
5. Gietz D, St Jean A, Woods RA, Schiestl RH (1992) Improved method for high efficiency transformation of intact yeast cells. Nucleic Acids Res 20: 1425
6. Huh WK, Falvo JV, Gerke LC, Carroll AS, Howson RW, Weissman JS, O'Shea EK (2003) Global analysis of protein localization in budding yeast. Nature 425: 686-691
7. Kadaba S, Krueger A, Trice T, Krecic AM, Hinnebusch AG, Anderson J (2004) Nuclear surveillance and degradation of hypomodified initiator tRNAMet in S. cerevisiae. Genes Dev 18: 1227-1240
8. Kuai L, Fang F, Butler JS, Sherman F (2004) Polyadenylation of rRNA in Saccharomyces cerevisiae. Proc Natl Acad Sci USA 101: 8581-8586
9. Kwak JE, Wang L, Ballantyne S, Kimble J, Wickens M (2004) Mammalian GLD-2 homologs are poly(A) polymerases. Proc Natl Acad Sci USA 101: 4407-4412
10. LaCava J, Houseley J, Saveanu C, Petfalski E, Thompson E, Jacquier A, Tollervey D (2005) RNA degradation by the exosome is promoted by a nuclear polyadenylation complex. Cell 21: 713-724
11. Mitchell P, Petfalski E, Shevchenko A, Mann M, Tollervey D (1997) The exosome; a conserved eukaryotic RNA processing complex containing multiple 3′ → 5′ exoribonuclease activities. Cell 91: 457-466
12. Qu LH, Henry Y, Nicoloso M, Michot B, Azum MC, Renalier MH, Caizergues-Ferrer M, Bachellerie JP (1995) U24, a novel intron-encoded small nucleolar RNA with two 12 nt long, phylogenetically conserved complementarities to 28S rRNA. Nucleic Acids Res 23: 2669-2676
13. Rigaut G, Shevchenko A, Rutz B, Wilm M, Mann M, Seraphin B (1999) A generic protein purification method for protein complex characterization and proteome exploration. Nat Biotechnol 17: 1030-1032
14. Saitoh S, Chabes A, McDonald WH, Thelander L, Yates JR, Russell P (2002) Cid13 is a cytoplasmic poly(A) polymerase that regulates ribonucleotide reductase mRNA. Cell 109: 563-573
15. Tollervey D (1987) A yeast small nuclear RNA is required for normal processing of pre-ribosomal RNA. EMBO J 6: 4169-4175
16. Vanacova S, Wolf J, Martin G, Blank D, Dettwiler S, Friedlein A, Langen H, Keith G, Keller W (2005) A new yeast poly(A) polymerase complex involved in RNA quality control. PLoS Biol 3: E189
17. van Hoof A, Lennertz P, Parker R (2000) Yeast exosome mutants accumulate 3′-extended polyadenylated forms of U4 small nuclear RNA and small nucleolar RNAs. Mol Cell Biol 20: 441-452
18. Wang L, Eckmann CR, Kadyk LC, Wickens M, Kimble J (2002) A regulatory cytoplasmic poly(A) polymerase in Caenorhabditis elegans. Nature 419: 312-316
19. Wang SW, Toda T, MacCallum R, Harris AL, Norbury C (2000) Cid1, a fission yeast protein required for S-M checkpoint control when DNA polymerase δ or ε is inactivated. Mol Cell Biol 20: 3234-3244
20. Wyers F et al (2005) Cryptic Pol II transcripts are degraded by a nuclear quality control pathway involving a new poly(A) polymerase. Cell 121: 725-737