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Volumn 15, Issue 1, 2006, Pages 30-33

Hormonal and cytokine effects of uric acid

Author keywords

Arteriosclerosis; Hypertension; Renal disease; Uric acid

Indexed keywords

ANTIOXIDANT; CYCLOOXYGENASE 2; CYTOKINE; MITOGEN ACTIVATED PROTEIN KINASE; MONOCYTE CHEMOTACTIC PROTEIN 1; ORGANIC ANION TRANSPORTER; PLATELET DERIVED GROWTH FACTOR A; PLATELET DERIVED GROWTH FACTOR C; TRANSCRIPTION FACTOR; URIC ACID;

EID: 33645730376     PISSN: 10624821     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.mnh.0000199010.33929.7f     Document Type: Review
Times cited : (68)

References (41)
  • 1
    • 0035024743 scopus 로고    scopus 로고
    • Functional reconstitution, membrane targeting, genomic structure and chromosomal localization of a human urate transporter
    • Lipkowitz MS, Leal-Pinto E, Rappoport JZ, et al. Functional reconstitution, membrane targeting, genomic structure and chromosomal localization of a human urate transporter. J Clin Invest 2001; 107:1103-1115.
    • (2001) J Clin Invest , vol.107 , pp. 1103-1115
    • Lipkowitz, M.S.1    Leal-Pinto, E.2    Rappoport, J.Z.3
  • 2
    • 0037161834 scopus 로고    scopus 로고
    • Molecular identification of a renal urate-anion exchanger that regulates blood urate levels
    • Enomoto A, Kimura H, Chairoungdua A, et al. Molecular identification of a renal urate-anion exchanger that regulates blood urate levels. Nature 2002; 417:447-452.
    • (2002) Nature , vol.417 , pp. 447-452
    • Enomoto, A.1    Kimura, H.2    Chairoungdua, A.3
  • 3
    • 0037213731 scopus 로고    scopus 로고
    • Urate transport via human PAH transporter hOAT1 and its gene structure
    • Ichida K, Hosoyamada M, Kimura H, et al. Urate transport via human PAH transporter hOAT1 and its gene structure. Kidney Int 2003; 63:143-155.
    • (2003) Kidney Int , vol.63 , pp. 143-155
    • Ichida, K.1    Hosoyamada, M.2    Kimura, H.3
  • 4
    • 0036914069 scopus 로고    scopus 로고
    • Mutations of the UMOD gene are responsible for medullary cystic kidney disease 2 and familial juvenile hyperuricaemic nephropathy
    • Hart TC, Gorry MC, Hart PS, et al. Mutations of the UMOD gene are responsible for medullary cystic kidney disease 2 and familial juvenile hyperuricaemic nephropathy. J Med Genet 2002; 39:882-892.
    • (2002) J Med Genet , vol.39 , pp. 882-892
    • Hart, T.C.1    Gorry, M.C.2    Hart, P.S.3
  • 5
    • 1542316154 scopus 로고    scopus 로고
    • Purine-rich foods, dairy and protein intake, and the risk of gout in men
    • Choi HK, Atkinson K, Karlson EW, et al. Purine-rich foods, dairy and protein intake, and the risk of gout in men. N Engl J Med 2004; 11;350:1093-1103. A 12-year prospective study of dietary factors associated with new cases of gout among 47,150 men which shows that meat and seafood consumption are associated with an increased risk of gout, whereas a consumption of dairy products is associated with a decreased risk.
    • (2004) N Engl J Med , vol.11 , Issue.350 , pp. 1093-1103
    • Choi, H.K.1    Atkinson, K.2    Karlson, E.W.3
  • 6
    • 33646338312 scopus 로고    scopus 로고
    • Fructose-induced hyperuricemia as a causal mechanism for the epidemic of the metabolic syndrome
    • (in press). [Epub ahead of print]
    • Nakagawa T, Tuttle KR, Short RA, Johnson RJ. Fructose-induced hyperuricemia as a causal mechanism for the epidemic of the metabolic syndrome Nature Clinical Practice Nephrology 2005 (in press). [Epub ahead of print].
    • (2005) Nature Clinical Practice Nephrology
    • Nakagawa, T.1    Tuttle, K.R.2    Short, R.A.3    Johnson, R.J.4
  • 7
    • 0027326867 scopus 로고
    • Gout and mechanisms of crystal-induced inflammation
    • Terkeltaub RA. Gout and mechanisms of crystal-induced inflammation. Curr Opin Rheumatol 1993; 5:510-516.
    • (1993) Curr Opin Rheumatol , vol.5 , pp. 510-516
    • Terkeltaub, R.A.1
  • 8
    • 0033005975 scopus 로고    scopus 로고
    • Reappraisal of the pathogenesis and consequences of hyperuricemia in hypertension, cardiovascular disease, and renal disease
    • Johnson RJ, Kivlighn SD, Kim Y-G, et al. Reappraisal of the pathogenesis and consequences of hyperuricemia in hypertension, cardiovascular disease, and renal disease. Am J Kidney Dis 1999; 33:225-234.
    • (1999) Am J Kidney Dis , vol.33 , pp. 225-234
    • Johnson, R.J.1    Kivlighn, S.D.2    Kim, Y.-G.3
  • 9
    • 0019787519 scopus 로고
    • Uric acid provides an antioxidant defense in humans against oxidant- and radical-causing aging and cancer: A hypothesis
    • U S A
    • Ames BN, Cathcart R, Schwiers E, et al. Uric acid provides an antioxidant defense in humans against oxidant- and radical-causing aging and cancer: a hypothesis. Proc Natl Acad Sci U S A 1981; 78:6853-6862.
    • (1981) Proc Natl Acad Sci , vol.78 , pp. 6853-6862
    • Ames, B.N.1    Cathcart, R.2    Schwiers, E.3
  • 10
    • 1042290474 scopus 로고    scopus 로고
    • Triuret: A novel product of peroxynitrite-mediated oxidation of urate
    • Robinson KM, Morre JT, Beckman JS. Triuret: a novel product of peroxynitrite-mediated oxidation of urate. Arch Biochem Biophys 2004; 423:213-217.
    • (2004) Arch Biochem Biophys , vol.423 , pp. 213-217
    • Robinson, K.M.1    Morre, J.T.2    Beckman, J.S.3
  • 11
    • 21344461736 scopus 로고    scopus 로고
    • Interactions of peroxynitrite with uric acid in the presence of ascorbate and thiols: Implications for uncoupling endothelial nitric oxide synthase
    • Kuzkaya N, Weissmann N, Harrison DG, Dikalov S. Interactions of peroxynitrite with uric acid in the presence of ascorbate and thiols: implications for uncoupling endothelial nitric oxide synthase. Biochem Pharmacol 2005; 70:343-354.
    • (2005) Biochem Pharmacol , vol.70 , pp. 343-354
    • Kuzkaya, N.1    Weissmann, N.2    Harrison, D.G.3    Dikalov, S.4
  • 12
    • 0036736747 scopus 로고    scopus 로고
    • Peroxidase properties of extracellular superoxide dismutase: Role of uric acid in modulating in vivo activity
    • Hink HU, Santanam N, Dikalov S, et al. Peroxidase properties of extracellular superoxide dismutase: role of uric acid in modulating in vivo activity. Arterioscler Thromb Vasc Biol 2002; 22:1402-1408.
    • (2002) Arterioscler Thromb Vasc Biol , vol.22 , pp. 1402-1408
    • Hink, H.U.1    Santanam, N.2    Dikalov, S.3
  • 13
    • 0035116154 scopus 로고    scopus 로고
    • Prospects for the treatment of multiple sclerosis by raising serum levels of uric acid, a scavenger of peroxynitrite
    • Koprowski H, Spitsin SV, Hooper DC. Prospects for the treatment of multiple sclerosis by raising serum levels of uric acid, a scavenger of peroxynitrite. Ann Neurol 2001; 49:139.
    • (2001) Ann Neurol , vol.49 , pp. 139
    • Koprowski, H.1    Spitsin, S.V.2    Hooper, D.C.3
  • 14
    • 0000116599 scopus 로고
    • The origin of man
    • Orowan E. The origin of man. Nature 1955; 175:683-684.
    • (1955) Nature , vol.175 , pp. 683-684
    • Orowan, E.1
  • 15
    • 0021678153 scopus 로고
    • Blood uric acid level and IQ: A study in twin families
    • Roma
    • Inouye E, Park KS, Asaka A. Blood uric acid level and IQ: a study in twin families. Acta Genet Med Gemellol (Roma) 1984; 33:237-242.
    • (1984) Acta Genet Med Gemellol , vol.33 , pp. 237-242
    • Inouye, E.1    Park, K.S.2    Asaka, A.3
  • 16
    • 0038119701 scopus 로고    scopus 로고
    • Is there a pathogenetic role for uric acid in hypertension and cardiovascular and renal disease?
    • Johnson RJ, Kang D-HH., Feig D, et al. Is there a pathogenetic role for uric acid in hypertension and cardiovascular and renal disease? Hypertension 2003; 41:1183-1190.
    • (2003) Hypertension , vol.41 , pp. 1183-1190
    • Johnson, R.J.1    Kang, D.-H.H.2    Feig, D.3
  • 17
    • 11244253742 scopus 로고    scopus 로고
    • Resurrection of uric acid as a causal risk factor for essential hypertension
    • Johnson RJ, Feig DI, Kang DH, Herrera-Acosta J. Resurrection of uric acid as a causal risk factor for essential hypertension. Hypertension 2005; 45:18-20.
    • (2005) Hypertension , vol.45 , pp. 18-20
    • Johnson, R.J.1    Feig, D.I.2    Kang, D.H.3    Herrera-Acosta, J.4
  • 18
    • 11244264034 scopus 로고    scopus 로고
    • Relations of serum uric acid to longitudinal blood pressure tracking and hypertension incidence
    • Sündstrom J, Sullivan L, D'Agostino RB, et al. Relations of serum uric acid to longitudinal blood pressure tracking and hypertension incidence. Hypertension 2005; 45:28-33. The authors showed that serum uric acid level was an independent predictor of hypertension incidence and longitudinal blood pressure progression at short-term follow-up in a community-based sample.
    • (2005) Hypertension , vol.45 , pp. 28-33
    • Sündstrom, J.1    Sullivan, L.2    D'Agostino, R.B.3
  • 19
    • 11244331349 scopus 로고    scopus 로고
    • Childhood uric acid predicts adult blood pressure: The Bogalusa Heart Study
    • Alper AB, Chen W, Yau L, et al. Childhood uric acid predicts adult blood pressure: the Bogalusa Heart Study. Hypertension 2005; 45:34-38. This 12-year follow-up study suggests that early elevations in serum uric acid levels may play a key role in the development of human hypertension.
    • (2005) Hypertension , vol.45 , pp. 34-38
    • Alper, A.B.1    Chen, W.2    Yau, L.3
  • 20
    • 0041803243 scopus 로고    scopus 로고
    • Serum uric acid and risk for development of hypertension and impaired fasting glucose or type II diabetes in Japanese male office workers
    • Nakanishi N, Okamato M, Yoshida H, et al. Serum uric acid and risk for development of hypertension and impaired fasting glucose or type II diabetes in Japanese male office workers. Eur J Epidemiol 2003; 18:523-530.
    • (2003) Eur J Epidemiol , vol.18 , pp. 523-530
    • Nakanishi, N.1    Okamato, M.2    Yoshida, H.3
  • 21
    • 0141962657 scopus 로고    scopus 로고
    • Serum uric acid and plasma norepinephrine concentrations predict subsequent weight gain and blood pressure elevation
    • Masuo K, Kawaguchi H, Mikami H, et al. Serum uric acid and plasma norepinephrine concentrations predict subsequent weight gain and blood pressure elevation. Hypertension 2003; 42:474-480.
    • (2003) Hypertension , vol.42 , pp. 474-480
    • Masuo, K.1    Kawaguchi, H.2    Mikami, H.3
  • 22
    • 0042334471 scopus 로고    scopus 로고
    • Hyperuricemia in childhood essential hypertension
    • Feig DI, Johnson RJ. Hyperuricemia in childhood essential hypertension. Hypertension 2003; 42:247-252.
    • (2003) Hypertension , vol.42 , pp. 247-252
    • Feig, D.I.1    Johnson, R.J.2
  • 23
    • 3042769305 scopus 로고    scopus 로고
    • Uric acid, nephron number, and the pathogenesis of essential hypertension
    • Feig DI, Nakagawa T, Karumanchi SA, et al. Uric acid, nephron number, and the pathogenesis of essential hypertension. Kidney International 2004; 66:281-287.
    • (2004) Kidney International , vol.66 , pp. 281-287
    • Feig, D.I.1    Nakagawa, T.2    Karumanchi, S.A.3
  • 24
    • 0035723995 scopus 로고    scopus 로고
    • Elevated uric acid increases blood pressure in the rat by a novel crystal-independent mechanism
    • Mazzali M, Hughes J, Kim YG, et al. Elevated uric acid increases blood pressure in the rat by a novel crystal-independent mechanism. Hypertension 2001; 38:1101-1106.
    • (2001) Hypertension , vol.38 , pp. 1101-1106
    • Mazzali, M.1    Hughes, J.2    Kim, Y.G.3
  • 25
    • 0036713048 scopus 로고    scopus 로고
    • Uric acid, hominoid evolution and the pathogenesis salt-sensitivity
    • Watanabe S, Kang DH, Feng L, et al. Uric acid, hominoid evolution and the pathogenesis salt-sensitivity. Hypertension 2002; 40:355-360.
    • (2002) Hypertension , vol.40 , pp. 355-360
    • Watanabe, S.1    Kang, D.H.2    Feng, L.3
  • 26
    • 0036083844 scopus 로고    scopus 로고
    • Hyperuricemia induces a primary arteriolopathy in rats by a blood pressure-independent mechanism
    • Mazzali M, Kanellis J, Han L, et al. Hyperuricemia induces a primary arteriolopathy in rats by a blood pressure-independent mechanism. Am J Physiol Renal Physiol 2002; 282:F991-F997.
    • (2002) Am J Physiol Renal Physiol , vol.282
    • Mazzali, M.1    Kanellis, J.2    Han, L.3
  • 27
    • 0037210124 scopus 로고    scopus 로고
    • Hyperuricemia causes glomerular hypertrophy in the rat
    • Nakagawa T, Mazzali M, Kang DH, et al. Hyperuricemia causes glomerular hypertrophy in the rat. Am J Nephrol 2003; 23:2-7.
    • (2003) Am J Nephrol , vol.23 , pp. 2-7
    • Nakagawa, T.1    Mazzali, M.2    Kang, D.H.3
  • 28
    • 0036892614 scopus 로고    scopus 로고
    • A role for uric acid in renal progression
    • Kang D, Nakagawa T, Feng L, et al. A role for uric acid in renal progression. J Am Soc Nephrol 2002; 13:2888-2897.
    • (2002) J Am Soc Nephrol , vol.13 , pp. 2888-2897
    • Kang, D.1    Nakagawa, T.2    Feng, L.3
  • 29
    • 26444494858 scopus 로고    scopus 로고
    • Uric acid causes vascular smooth muscle cell proliferation by entering cells via a functional urate transporter
    • Kang DH, Han L, Ouyang X, et al. Uric acid causes vascular smooth muscle cell proliferation by entering cells via a functional urate transporter. Am J Nephrol 2005; 25:425-433. This paper established that urate enters VSMC by both voltage-sensitive and an organic anionic transport system.
    • (2005) Am J Nephrol , vol.25 , pp. 425-433
    • Kang, D.H.1    Han, L.2    Ouyang, X.3
  • 30
    • 33645461474 scopus 로고    scopus 로고
    • Uric acid induced C-reactive protein (CRP) expression: Implication on cell proliferation and nitric oxide production in human vascular cells
    • in press
    • Kang D-H, Park SK, Lee IK, Johnson RJ. Uric acid induced C-reactive protein (CRP) expression: implication on cell proliferation and nitric oxide production in human vascular cells. J Am Soc Nephrol (in press).
    • J Am Soc Nephrol
    • Kang, D.-H.1    Park, S.K.2    Lee, I.K.3    Johnson, R.J.4
  • 31
    • 0025837540 scopus 로고
    • Uric acid stimulates vascular smooth muscle cell proliferation by increasing platelet-derived growth factor A-chain expression
    • Rao GN, Corson MA, Berk BC. Uric acid stimulates vascular smooth muscle cell proliferation by increasing platelet-derived growth factor A-chain expression. J Biol Chem 1991; 266:8604-8608.
    • (1991) J Biol Chem , vol.266 , pp. 8604-8608
    • Rao, G.N.1    Corson, M.A.2    Berk, B.C.3
  • 32
    • 0038579374 scopus 로고    scopus 로고
    • Uric acid stimulates monocyte chemoattractant protein-1 production in vascular smooth muscle cells via mitogen-activated protein kinase and cyclooxygenase-2
    • Kanellis J, Watanabe S, Li JH, et al. Uric acid stimulates monocyte chemoattractant protein-1 production in vascular smooth muscle cells via mitogen-activated protein kinase and cyclooxygenase-2. Hypertension 2003; 41:1287-1293.
    • (2003) Hypertension , vol.41 , pp. 1287-1293
    • Kanellis, J.1    Watanabe, S.2    Li, J.H.3
  • 33
    • 20244365646 scopus 로고    scopus 로고
    • Hyperuricemia induces endothelial dysfunction
    • Khosla UM, Zharikov S, Finch JL, et al. Hyperuricemia induces endothelial dysfunction. Kidney Int 2005; 67:1739-1742. This study demonstrates that uric acid can induce endothelial dysfunction both in vitro and in vivo.
    • (2005) Kidney Int , vol.67 , pp. 1739-1742
    • Khosla, U.M.1    Zharikov, S.2    Finch, J.L.3
  • 35
    • 10944243094 scopus 로고    scopus 로고
    • Mild hyperuricemia induces severe cortical vasoconstriction and perpetuates glomerular hypertension in normal rats and in experimental chronic renal failure
    • Sánchez-Lozada LG, Tapia E, Santamaria J, et al. Mild hyperuricemia induces severe cortical vasoconstriction and perpetuates glomerular hypertension in normal rats and in experimental chronic renal failure. Kidney Int 2005; 67:237-247.
    • (2005) Kidney Int , vol.67 , pp. 237-247
    • Sánchez-Lozada, L.G.1    Tapia, E.2    Santamaria, J.3
  • 36
    • 15744385092 scopus 로고    scopus 로고
    • A unifying pathway for essential hypertension
    • Johnson RJ, Rodriguez-Iturbe B, Kang DH, et al. A unifying pathway for essential hypertension. Am J Hypertens 2005; 18:431-440. This paper presents a novel theory that unites many of the previous hypotheses on the etiology of hypertension.
    • (2005) Am J Hypertens , vol.18 , pp. 431-440
    • Johnson, R.J.1    Rodriguez-Iturbe, B.2    Kang, D.H.3
  • 37
    • 0036601262 scopus 로고    scopus 로고
    • Restoration of glomerular haemodynamics and renal injury independent of arterial hypertension in rats with subtotal renal ablation
    • Herrera-Acosta J, Tapia E, Sánchez-Lozada LG, et al. Restoration of glomerular haemodynamics and renal injury independent of arterial hypertension in rats with subtotal renal ablation. J Hypertens Suppl 2002; 20:S29-S35.
    • (2002) J Hypertens Suppl , vol.20
    • Herrera-Acosta, J.1    Tapia, E.2    Sánchez-Lozada, L.G.3
  • 38
    • 27744608003 scopus 로고    scopus 로고
    • Essential hypertension, progressive renal disease and uric acid: A pathogenetic link?
    • Johnson RJ, Segal MS, Srinivas TR, et al. Essential hypertension, progressive renal disease and uric acid: a pathogenetic link? J Am Soc Nephrol 2005; 16:1909-1919. The authors hypothesize about the pathogenetic pathways mediating progressive renal damage in hypertensive subjects.
    • (2005) J Am Soc Nephrol , vol.16 , pp. 1909-1919
    • Johnson, R.J.1    Segal, M.S.2    Srinivas, T.R.3
  • 39
    • 13444254470 scopus 로고    scopus 로고
    • Uric acid correlates with the severity of histopathological parameters in IgA nephropathy
    • Myllymaki J, Honkanen T, Syrjanen J, et al. Uric acid correlates with the severity of histopathological parameters in IgA nephropathy. Nephrol Dial Transplant 2005; 20:89-95.
    • (2005) Nephrol Dial Transplant , vol.20 , pp. 89-95
    • Myllymaki, J.1    Honkanen, T.2    Syrjanen, J.3
  • 40
    • 17244373729 scopus 로고    scopus 로고
    • Uric acid, microalbuminuria, and cardiovascular events in high risk patients
    • Short RA, Johnson RJ, Tuttle KR. Uric acid, microalbuminuria, and cardiovascular events in high risk patients. Am J Nephrol 2005; 25:36-44.
    • (2005) Am J Nephrol , vol.25 , pp. 36-44
    • Short, R.A.1    Johnson, R.J.2    Tuttle, K.R.3
  • 41
    • 23744490953 scopus 로고    scopus 로고
    • Correlation of uric acid and urinary albumin excretion rate in patients with type 2 diabetes mellitus in Taiwan
    • Tseng CH. Correlation of uric acid and urinary albumin excretion rate in patients with type 2 diabetes mellitus in Taiwan. Kidney Int 2005; 68:796-801.
    • (2005) Kidney Int , vol.68 , pp. 796-801
    • Tseng, C.H.1


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