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Volumn 15, Issue 4, 2006, Pages 399-407

Investigational drugs for endometriosis

Author keywords

Angiogenesis; Aromatase; Endometriosis; Estrogen receptor agonist; Gonadotropin releasing hormone antagonists; Immune; Matrix metalloprotease; Pelvic pain; Selective progesterone receptor modulator

Indexed keywords

ANASTROZOLE; ANGIOGENESIS INHIBITOR; ANTIGESTAGEN; AROMATASE INHIBITOR; ASOPRISNIL; CETRORELIX; ESTRADIOL; ESTROGEN RECEPTOR BETA; ETHINYLESTRADIOL PLUS LEVONORGESTREL; GONADORELIN AGONIST; GONADORELIN ANTAGONIST; HORMONE RECEPTOR STIMULATING AGENT; IMMUNOMODULATING AGENT; J 1042; J 912; J 956; LETROZOLE; MATRIX METALLOPROTEINASE INHIBITOR; MEDROXYPROGESTERONE ACETATE; MESOPROGESTIN DERIVATIVE; MIFEPRISTONE; NEW DRUG; NORETHISTERONE ACETATE; ONAPRISTONE; PROGESTERONE; PROGESTERONE RECEPTOR MODULATOR; THALIDOMIDE; UNCLASSIFIED DRUG; UNINDEXED DRUG; ZK 135695; ZK 137316;

EID: 33645723454     PISSN: 13543784     EISSN: None     Source Type: Journal    
DOI: 10.1517/13543784.15.4.399     Document Type: Review
Times cited : (7)

References (61)
  • 1
    • 1542619801 scopus 로고    scopus 로고
    • Optimizing gonadotropin-releasing hormone agonist therapy in women with endometriosis
    • OLIVE DL: Optimizing gonadotropin-releasing hormone agonist therapy in women with endometriosis. Treat. Endocrinol. (2004) 3(2):83-89.
    • (2004) Treat. Endocrinol. , vol.3 , Issue.2 , pp. 83-89
    • Olive, D.L.1
  • 2
    • 33645726892 scopus 로고
    • Efficacy and safety considerations in women with uterine leiomyomas treated with gonadotropin-releasing hormone agonists: The estrogen threshold hypothesis
    • FRIEDMAN AJ, LOBEL SM, REIN MS, BARBIERI RL: Efficacy and safety considerations in women with uterine leiomyomas treated with gonadotropin-releasing hormone agonists: the estrogen threshold hypothesis. Am. J. Obstet. Gynecol. (1990) 78:943.
    • (1990) Am. J. Obstet. Gynecol. , vol.78 , pp. 943
    • Friedman, A.J.1    Lobel, S.M.2    Rein, M.S.3    Barbieri, R.L.4
  • 3
    • 0023131202 scopus 로고
    • The effect of a luteinizing hormone-releasing hormone antagonist on experimental endometriosis in the rat
    • JONES RC: The effect of a luteinizing hormone-releasing hormone antagonist on experimental endometriosis in the rat. Acta Endocrinol. (1987) 114:370-382.
    • (1987) Acta Endocrinol. , vol.114 , pp. 370-382
    • Jones, R.C.1
  • 4
    • 33645725060 scopus 로고    scopus 로고
    • Initial safety profile and hormonal dose response characteristics of the pure GnRH antagonist, Abarelix-depot, in women with endometriosis
    • San Diego, USA (24 - 27 February 2005) (Poster)
    • MARTHA PM, GRAY ME, CAMPION M et al: Initial safety profile and hormonal dose response characteristics of the pure GnRH antagonist, Abarelix-depot, in women with endometriosis. VIII World Congress on Endometriosis, San Diego, USA (24 - 27 February 2005) (Poster).
    • VIII World Congress on Endometriosis
    • Martha, P.M.1    Gray, M.E.2    Campion, M.3
  • 6
    • 0033815518 scopus 로고    scopus 로고
    • Molecular basis for treating endometriosis with aromatase inhibitors
    • BULUN SE, ZEITOUN KM, TAKAYAMA K et al.: Molecular basis for treating endometriosis with aromatase inhibitors. Hum. Reprod. Update (2000) 6:413-418.
    • (2000) Hum. Reprod. Update , vol.6 , pp. 413-418
    • Bulun, S.E.1    Zeitoun, K.M.2    Takayama, K.3
  • 7
    • 26444450506 scopus 로고    scopus 로고
    • Aromatase inhibitors and cylooxygenase-2 (COX-2) inhibitors in endometriosis: New questions-old answers?
    • EBERT AD, BARTLEY J, DAVID M: Aromatase inhibitors and cylooxygenase-2 (COX-2) inhibitors in endometriosis: new questions-old answers? Eur. J. Obstet. Gynecol. Reprod. Biol. (2005) 122:144-150.
    • (2005) Eur. J. Obstet. Gynecol. Reprod. Biol. , vol.122 , pp. 144-150
    • Ebert, A.D.1    Bartley, J.2    David, M.3
  • 8
    • 23744453611 scopus 로고    scopus 로고
    • Effects of aromatase inhibitors on proliferation and apoptosis in eutopic endometrial cell cultures from patients with endometriosis
    • MERSEMAN GF, BILOTAS M, ABELLO V et al: Effects of aromatase inhibitors on proliferation and apoptosis in eutopic endometrial cell cultures from patients with endometriosis. Fertil. Steril. (2005) 84(2):459-463.
    • (2005) Fertil. Steril. , vol.84 , Issue.2 , pp. 459-463
    • Merseman, G.F.1    Bilotas, M.2    Abello, V.3
  • 9
    • 0029869714 scopus 로고    scopus 로고
    • Studies on the effect of the new non-steroidal aromatase inhibitor fadrozole hydrochloride in an endometriosis model in rats
    • YANO S, IKEGAMI Y, NAKAO K: Studies on the effect of the new non-steroidal aromatase inhibitor fadrozole hydrochloride in an endometriosis model in rats. Arzneimitelforschung (1996) 46(2):192-195.
    • (1996) Arzneimitelforschung , vol.46 , Issue.2 , pp. 192-195
    • Yano, S.1    Ikegami, Y.2    Nakao, K.3
  • 10
    • 0031443052 scopus 로고    scopus 로고
    • Inhibitory effects of a novel aromatase inhibitor, YM511, on growth of endometrial explants and insulin-like growth factor-I gene expression in rats with experimental endometriosis
    • KUDOH M, SUSAKI Y, IDEYAMA Y, NANYA T, MORI M, SHIKAMA H: Inhibitory effects of a novel aromatase inhibitor, YM511, on growth of endometrial explants and insulin-like growth factor-I gene expression in rats with experimental endometriosis. J. Steroid Biochem. Mol. Bio. (1997) 63(1-3):75-80.
    • (1997) J. Steroid Biochem. Mol. Bio. , vol.63 , Issue.1-3 , pp. 75-80
    • Kudoh, M.1    Susaki, Y.2    Ideyama, Y.3    Nanya, T.4    Mori, M.5    Shikama, H.6
  • 11
    • 0442291985 scopus 로고    scopus 로고
    • Treatment of severe endometriosis with an aromatase inhibitor in a young ovariectomized woman
    • RAZZI S, FAVA A, SARTINI A, DE SIMONE S, COBELLIS L, PETRAGLIA F: Treatment of severe endometriosis with an aromatase inhibitor in a young ovariectomized woman. BJOG (2004) 111:182-184.
    • (2004) BJOG , vol.111 , pp. 182-184
    • Razzi, S.1    Fava, A.2    Sartini, A.3    De Simone, S.4    Cobellis, L.5    Petraglia, F.6
  • 13
    • 28844453666 scopus 로고    scopus 로고
    • Successful treatment of an aggressive recurrent post-menopausal endometriosis with an aromatase inhibitor
    • FATEMI HM, AL-TURKI HA, PAPANIKOLAOU E, KOSMAS L, DE SUTTER P, DEVROEY P: Successful treatment of an aggressive recurrent post-menopausal endometriosis with an aromatase inhibitor. Reprod. Biomed. Online (2005) 11(4):455-457.
    • (2005) Reprod. Biomed. Online , vol.11 , Issue.4 , pp. 455-457
    • Fatemi, H.M.1    Al-Turki, H.A.2    Papanikolaou, E.3    Kosmas, L.4    Desutter, P.5    Devroey, P.6
  • 14
    • 2342628482 scopus 로고    scopus 로고
    • Successful treatment of severe endometriosis in two premenopausal women with an aromatase inhibitor
    • SHIPPEN ER, WEST WJ Jr: Successful treatment of severe endometriosis in two premenopausal women with an aromatase inhibitor. Fertil. Steril. (2004) 81(5):1395-1398.
    • (2004) Fertil. Steril. , vol.81 , Issue.5 , pp. 1395-1398
    • Shippen, E.R.1    West Jr., W.J.2
  • 15
    • 0347287105 scopus 로고    scopus 로고
    • The effects of post-surgical administration of goserelin plus anastrozole compared to goserelin alone in patients with severe endometriosis: A prospective randomized trial
    • SOYSAL S, SOYSAL ME, OZER S, GUL N, GEZGIN T: The effects of post-surgical administration of goserelin plus anastrozole compared to goserelin alone in patients with severe endometriosis: a prospective randomized trial. Hum. Reprod. (2004) 19(1):160-167.
    • (2004) Hum. Reprod. , vol.19 , Issue.1 , pp. 160-167
    • Soysal, S.1    Soysal, M.E.2    Ozer, S.3    Gul, N.4    Gezgin, T.5
  • 16
    • 1242306539 scopus 로고    scopus 로고
    • Treatment of endometriosis and chronic pelvic pain with letrozole and norethindrone acetate: A pilot study
    • AILAWADI RK, JOBANPUTRA S, KATARIA M, GURATES B, BULUN SE: Treatment of endometriosis and chronic pelvic pain with letrozole and norethindrone acetate: a pilot study. Fertil. Steril. (2004) 81(2)-290-296.
    • (2004) Fertil. Steril. , vol.81 , Issue.2 , pp. 290-296
    • Ailawadi, R.K.1    Jobanputra, S.2    Kataria, M.3    Gurates, B.4    Bulun, S.E.5
  • 18
    • 0033645919 scopus 로고    scopus 로고
    • Antiproliferative effects of progesterone antagonists and progesterone receptor modulators on the endometrium
    • CHWALISZ K, BRENNER RM, FUHRMANN UU et al.: Antiproliferative effects of progesterone antagonists and progesterone receptor modulators on the endometrium. Steroids (2000) 65(10-11):741-751.
    • (2000) Steroids , vol.65 , Issue.10-11 , pp. 741-751
    • Chwalisz, K.1    Brenner, R.M.2    Fuhrmann, U.U.3
  • 19
    • 0002708343 scopus 로고
    • RU38486: An original multifaceted antihormone in vivo
    • Agarwal M (Ed.), Walter de Gruy and Co., Berlin, Germany
    • PHILIBERT D: RU38486: an original multifaceted antihormone in vivo. In: Adrenal steroid antagonism, Agarwal M (Ed.), Walter de Gruy and Co., Berlin, Germany (1984):77-101.
    • (1984) Adrenal Steroid Antagonism , pp. 77-101
    • Philibert, D.1
  • 20
    • 0347627644 scopus 로고    scopus 로고
    • Progesterone receptor transcription and non-transcription signaling mechanisms
    • LEONHARDT SA, BOONYARATANAKORNKIT V, EDWARDS DP: Progesterone receptor transcription and non-transcription signaling mechanisms. Steroids (2003) 68(10-13):761-770.
    • (2003) Steroids , vol.68 , Issue.10-13 , pp. 761-770
    • Leonhardt, S.A.1    Boonyaratanakornkit, V.2    Edwards, D.P.3
  • 21
    • 0033651180 scopus 로고    scopus 로고
    • Progesterone receptor modulators and progesterone antagonists in women's health
    • SPITZ IM, CHWALISZ K: Progesterone receptor modulators and progesterone antagonists in women's health. Steroids (2000) 65(10-11):807-815.
    • (2000) Steroids , vol.65 , Issue.10-11 , pp. 807-815
    • Spitz, I.M.1    Chwalisz, K.2
  • 22
    • 0027530867 scopus 로고
    • Time-related effects of Mifepristone treatment in experimentally induced endometriosis in the rat
    • TJADEN B, GALETTO D, WOODRUFF JD, ROCK JA: Time-related effects of Mifepristone treatment in experimentally induced endometriosis in the rat. Fertil. Steril. (1993) 59(2):437-440.
    • (1993) Fertil. Steril. , vol.59 , Issue.2 , pp. 437-440
    • Tjaden, B.1    Galetto, D.2    Woodruff, J.D.3    Rock, J.A.4
  • 23
    • 0029940788 scopus 로고    scopus 로고
    • Antiprogestin and/or Gonadotropin-releasing hormone agonist for endometriosis treatment and bone maintenance: A 1-year primate study
    • GROW DR, WILLIAMS RF, HSIU JG, HODGEN GD: Antiprogestin and/or Gonadotropin-releasing hormone agonist for endometriosis treatment and bone maintenance: a 1-year primate study. J. Clin. Endocrinol. Metab. (1996) 81(5):1993-1999.
    • (1996) J. Clin. Endocrinol. Metab. , vol.81 , Issue.5 , pp. 1993-1999
    • Grow, D.R.1    Williams, R.F.2    Hsiu, J.G.3    Hodgen, G.D.4
  • 24
    • 0028272514 scopus 로고
    • Clinical efficacy of the antiprogesterone mifepristone in the treatment of endometriosis and uterine fibroids
    • KETTEL LM, MURPHY AA, MORALES AJ, YEN SS: Clinical efficacy of the antiprogesterone mifepristone in the treatment of endometriosis and uterine fibroids. Hum. Reprod. (1994) 9(Suppl. 1):116-120.
    • (1994) Hum. Reprod. , vol.9 , Issue.SUPPL. 1 , pp. 116-120
    • Kettel, L.M.1    Murphy, A.A.2    Morales, A.J.3    Yen, S.S.4
  • 26
    • 0031777147 scopus 로고    scopus 로고
    • Preliminary reports on the treatment of endometriosis with low-dose RU486 (mifepristone)
    • KETTEL LM, MURPHY AA, MORALES AJ, YEN SS: Preliminary reports on the treatment of endometriosis with low-dose RU486 (mifepristone). Am. J. Obstet. Gynecol, (1998) 178(6):1151-1156.
    • (1998) Am. J. Obstet. Gynecol. , vol.178 , Issue.6 , pp. 1151-1156
    • Kettel, L.M.1    Murphy, A.A.2    Morales, A.J.3    Yen, S.S.4
  • 27
    • 33645720690 scopus 로고    scopus 로고
    • Mifepristone following conservative surgery in the treatment of endometriosis
    • JIANG J, LU J, WU R: Mifepristone following conservative surgery in the treatment of endometriosis. Zhonghua Fu Chan Ke Za Zhi (2001) 36(12):717-720.
    • (2001) Zhonghua Fu Chan Ke Za Zhi , vol.36 , Issue.12 , pp. 717-720
    • Jiang, J.1    Lu, J.2    Wu, R.3
  • 28
    • 3042570806 scopus 로고    scopus 로고
    • Systematic review of Mifepristone for the treatment of uterine leioyomata
    • STEINAUER J, PRITTS EA, JACKSON R, JACOBY AF: Systematic review of Mifepristone for the treatment of uterine leioyomata. Obstet. Gynecol. (2004) 103(6)1331-1336.
    • (2004) Obstet. Gynecol. , vol.103 , Issue.6 , pp. 1331-1336
    • Steinauer, J.1    Pritts, E.A.2    Jackson, R.3    Jacoby, A.F.4
  • 30
    • 33645703069 scopus 로고    scopus 로고
    • Medical therapy of endometriosis
    • Olive DL (Ed.), Taylor and Francis, New York, USA
    • OLIVE DL: Medical therapy of endometriosis. In: Endometriosis in clinical practice, Olive DL (Ed.), Taylor and Francis, New York, USA (2005):173-193.
    • (2005) Endometriosis in Clinical Practice , pp. 173-193
    • Olive, D.L.1
  • 31
    • 14844306692 scopus 로고    scopus 로고
    • Angiostatic agents prevent the development of endometriosis-like lesions in the chicken chorioallantoic membrane
    • NAP AW, DUNSELMAN GA, GRIFFIOEN AW, MAYO KH, EVERS JL, GROOTHUIS PG: Angiostatic agents prevent the development of endometriosis-like lesions in the chicken chorioallantoic membrane. Fertil. Steril. (2005) 83(3):793-795.
    • (2005) Fertil. Steril. , vol.83 , Issue.3 , pp. 793-795
    • Nap, A.W.1    Dunselman, G.A.2    Griffioen, A.W.3    Mayo, K.H.4    Evers, J.L.5    Groothuis, P.G.6
  • 34
    • 25844486122 scopus 로고    scopus 로고
    • Endostatin inhibits the growth of endometriosis lesions but does not affect fertility
    • BECKER CM, SAMPSON DA, RUPNICK MA et al: Endostatin inhibits the growth of endometriosis lesions but does not affect fertility. Fertil. Steril. (2005) 84(Suppl. 2):1144-1155.
    • (2005) Fertil. Steril. , vol.84 , Issue.SUPPL. 2 , pp. 1144-1155
    • Becker, C.M.1    Sampson, D.A.2    Rupnick, M.A.3
  • 35
  • 37
    • 0030317405 scopus 로고    scopus 로고
    • Matrix metalloproteinases in normal menstruation
    • SALAMONSEN LA, WOOLLEY DE: Matrix metalloproteinases in normal menstruation. Hum. Reprod. (1996) 11:124-133.
    • (1996) Hum. Reprod. , vol.11 , pp. 124-133
    • Salamonsen, L.A.1    Woolley, D.E.2
  • 38
    • 10744227350 scopus 로고    scopus 로고
    • Expression of several components of the plasminogen activator and matrix metalloproteinase systems in endometriosis
    • GILABERT-ESTELLES J, ESTELLS A, GILABERT J et al: Expression of several components of the plasminogen activator and matrix metalloproteinase systems in endometriosis. Hum. Reprod. (2003) 18(7):1516-1522.
    • (2003) Hum. Reprod. , vol.18 , Issue.7 , pp. 1516-1522
    • Gilabert-Estelles, J.1    Estells, A.2    Gilabert, J.3
  • 39
    • 0036813755 scopus 로고    scopus 로고
    • Gene expression of adhesion molecules and matrix metalloproteinases in endometriosis
    • UEDA M, YAMASHITA Y, TAKEHARA M et al.: Gene expression of adhesion molecules and matrix metalloproteinases in endometriosis. Gynecol. Endocrinol. (2002) 16:391-402.
    • (2002) Gynecol. Endocrinol. , vol.16 , pp. 391-402
    • Ueda, M.1    Yamashita, Y.2    Takehara, M.3
  • 40
    • 12144283018 scopus 로고    scopus 로고
    • Eutopic endometrium and peritoneal, ovarian and bowel endometriotic tissue express a different profile of matrix metalloproteinases-2, -3, and -11, and of tissue inhibitor metalloproteinases-1 and -2
    • UZAN C, CORTEZ A, FAUVET R, SIFFROI JP, DARAI E: Eutopic endometrium and peritoneal, ovarian and bowel endometriotic tissue express a different profile of matrix metalloproteinases-2, -3, and -11, and of tissue inhibitor metalloproteinases-1 and -2. Birchows Arch. (2004) 445(6):603-609.
    • (2004) Birchows Arch. , vol.445 , Issue.6 , pp. 603-609
    • Uzan, C.1    Cortez, A.2    Fauvet, R.3    Siffroi, J.P.4    Darai, E.5
  • 41
    • 25144506953 scopus 로고    scopus 로고
    • Matrix metalloproteinase-13 and membrane type-1 matrix metalloproteinase in peritoneal fluid of women with endometriosis
    • LAUDANSKI P, SZAMATOWICZ J, RAMEL P: Matrix metalloproteinase-13 and membrane type-1 matrix metalloproteinase in peritoneal fluid of women with endometriosis. Gynecol. Endocrinol. (2005) 21(2):106-110.
    • (2005) Gynecol. Endocrinol. , vol.21 , Issue.2 , pp. 106-110
    • Laudanski, P.1    Szamatowicz, J.2    Ramel, P.3
  • 42
    • 0035044623 scopus 로고    scopus 로고
    • Presence of estrogen receptor β in the human endometrium throughout the cycle: Expression in glandular, stromal, and vascular cells
    • LECCE G, MEDURI G, ANCELIN M, BERFERON C, PERROT-APPLANAT M: Presence of estrogen receptor β in the human endometrium throughout the cycle: expression in glandular, stromal, and vascular cells. J. Clin. Endocrinol. Metab. (2001) 86:1379-1386.
    • (2001) J. Clin. Endocrinol. Metab. , vol.86 , pp. 1379-1386
    • Lecce, G.1    Meduri, G.2    Ancelin, M.3    Berferon, C.4    Perrot-applanat, M.5
  • 43
    • 0032769954 scopus 로고    scopus 로고
    • Expression of estrogen receptor α and β in ovarian endometriomata
    • FUJIMOTO J, HIROSE R, SAKAGUCHI H, TAMAYA T: Expression of estrogen receptor α and β in ovarian endometriomata. Mol. Hum. Reprod. (1999) 5:742-747.
    • (1999) Mol. Hum. Reprod. , vol.5 , pp. 742-747
    • Fujimoto, J.1    Hirose, R.2    Sakaguchi, H.3    Tamaya, T.4
  • 44
    • 25844494494 scopus 로고    scopus 로고
    • Estrogen receptor β and matrix metalloproteinase-1 are coexpressed in uterine endometrium and endometriotic lesions of patients with endometriosiS
    • HUDELIST G, KECKSTEIN J, CZERWENKA K et al: Estrogen receptor β and matrix metalloproteinase-1 are coexpressed in uterine endometrium and endometriotic lesions of patients with endometriosiS. Fertil. Steril. (2005) 84(Suppl. 2):1249-1256.
    • (2005) Fertil. Steril. , vol.84 , Issue.SUPPL. 2 , pp. 1249-1256
    • Hudelist, G.1    Keckstein, J.2    Czerwenka, K.3
  • 45
    • 18744367571 scopus 로고    scopus 로고
    • A selective estrogen receptor-β agonist causes lesion regression in an experimentally induced model of endometriosis
    • HARRIS HA, BRUNER-TRAN KL, ZRANG X, OSTEEN KG, LYTTLE CR: A selective estrogen receptor-β agonist causes lesion regression in an experimentally induced model of endometriosis. Hum. Reprod. (2005) 20(4):936-941.
    • (2005) Hum. Reprod. , vol.20 , Issue.4 , pp. 936-941
    • Harris, H.A.1    Bruner-Tran, K.L.2    Zrang, X.3    Osteen, K.G.4    Lyttle, C.R.5
  • 46
    • 0036231813 scopus 로고    scopus 로고
    • Uterine chemokines in reproductive physiology and pathology
    • KAYISLI UA, MAHUTTE NG, ARICI A: Uterine chemokines in reproductive physiology and pathology. Am. J. Reprod. Immunol. (2002) 47(4):213-221.
    • (2002) Am. J. Reprod. Immunol. , vol.47 , Issue.4 , pp. 213-221
    • Kayisli, U.A.1    Mahutte, N.G.2    Arici, A.3
  • 48
    • 0036214978 scopus 로고    scopus 로고
    • Regulation and modulation of abnormal immune responses in endometriosis
    • SIDELL N, HAN SW, PARTHASARATHY S: Regulation and modulation of abnormal immune responses in endometriosis. Ann. NY Acad. Sci. (2002) 955:159-173.
    • (2002) Ann. NY Acad. Sci. , vol.955 , pp. 159-173
    • Sidell, N.1    Han, S.W.2    Parthasarathy, S.3
  • 49
    • 33645704980 scopus 로고    scopus 로고
    • Endometrial ability to implant in ectopic sites can be prevented by interleukin-12 in a murine model of endometriosis
    • SOMIGLIANA E, VIGANO P, ROSSI G, CARINELLI S, VIGNALI M, PANINA-BORDIGNON P: Endometrial ability to implant in ectopic sites can be prevented by interleukin-12 in a murine model of endometriosis. Hum. Reprod. (1999) 17:555-559.
    • (1999) Hum. Reprod. , vol.17 , pp. 555-559
    • Somigliana, E.1    Vigano, P.2    Rossi, G.3    Carinelli, S.4    Vignali, M.5    Panina-Bordignon, P.6
  • 50
    • 0033168742 scopus 로고    scopus 로고
    • Regression of endometrial explants in a rat model of endometriosis treated with the immune modulators loxoribine and levamisole
    • KEENAN JA, WILLIAMS-BOYCE PK, MASSEY PJ, CHEN TT, CLAUDLE MR, BUKOVSKY A: Regression of endometrial explants in a rat model of endometriosis treated with the immune modulators loxoribine and levamisole. Fertil. Seril. (1999) 72:135-141.
    • (1999) Fertil. Seril. , vol.72 , pp. 135-141
    • Keenan, J.A.1    Williams-Boyce, P.K.2    Massey, P.J.3    Chen, T.T.4    Claudle, M.R.5    Bukovsky, A.6
  • 51
    • 5044242957 scopus 로고    scopus 로고
    • Peroxisome proliferators-activated receptor-γ induces regression of endometrial explants in a rat model of endometriosis
    • LEBOVIC DI, KIR M, CASEY CL: Peroxisome proliferators-activated receptor-γ induces regression of endometrial explants in a rat model of endometriosis. Fertil. Steril. (2004) 82(Suppl. 3):1008-1013.
    • (2004) Fertil. Steril. , vol.82 , Issue.SUPPL. 3 , pp. 1008-1013
    • Lebovic, D.I.1    Kir, M.2    Casey, C.L.3
  • 54
    • 0036787872 scopus 로고    scopus 로고
    • 2β therapy after conservative surgery for endometriosis and postoperative medical treatment with depot gonadotropin-releasing hormone analog: A randomized clinical trial
    • 2β therapy after conservative surgery for endometriosis and postoperative medical treatment with depot gonadotropin-releasing hormone analog: a randomized clinical trial. Fertil. Steril. (2002) 78(4):705-711.
    • (2002) Fertil. Steril. , vol.78 , Issue.4 , pp. 705-711
    • Acien, P.1    Quereda, F.2    Campos, A.3    Gomez-Torres, M.J.4    Velasco, I.5    Gutierrez, M.6
  • 55
    • 0026085362 scopus 로고
    • Immunomodulation with pentoxifylline abrogates macrophage-mediated infertility in an in vivo model: A paradigm for a novel approach to the treatment of endometriosis-associated infertility
    • STEINLEITNER A, LAMBERT H, ROY S: Immunomodulation with pentoxifylline abrogates macrophage-mediated infertility in an in vivo model: a paradigm for a novel approach to the treatment of endometriosis-associated infertility. Fertil. Steril. (1991) 55:26-31.
    • (1991) Fertil. Steril. , vol.55 , pp. 26-31
    • Steinleitner, A.1    Lambert, H.2    Roy, S.3
  • 56
    • 0030828629 scopus 로고    scopus 로고
    • Pentoxifylline versus placebo in the treatment of infertility associated with minimal or mild endometriosis: A pilot randomized clinical trial
    • BALASCHI J, CREUS M, FABREGUES F et al: Pentoxifylline versus placebo in the treatment of infertility associated with minimal or mild endometriosis: a pilot randomized clinical trial. Hum. Reprod. (1997) 12:2046-2050.
    • (1997) Hum. Reprod. , vol.12 , pp. 2046-2050
    • Balaschi, J.1    Creus, M.2    Fabregues, F.3
  • 57
    • 28144441055 scopus 로고    scopus 로고
    • Experimental intestinal endometriosis is characterized by increased levels of soluble TNFRSF1B and downregulation of TNFRSF1A and TNFRSF1B gene expression
    • ROJAS-CARTAGENA C, APPLEYARD CB, SANTIAGO OI, FLORES I: Experimental intestinal endometriosis is characterized by increased levels of soluble TNFRSF1B and downregulation of TNFRSF1A and TNFRSF1B gene expression. Biol. Reprod. (2005) 73(6):1211-1218.
    • (2005) Biol. Reprod. , vol.73 , Issue.6 , pp. 1211-1218
    • Rojas-cartagena, C.1    Appleyard, C.B.2    Santiago, O.I.3    Flores, I.4
  • 58
    • 0142058123 scopus 로고    scopus 로고
    • Effect of IL-I-β and TNF-α on the expression of monocyte chemotactic protein-1 in endometriotic cells
    • GAO Y, LUO L, HE F: Effect of IL-I-β and TNF-α on the expression of monocyte chemotactic protein-1 in endometriotic cells. J. Tongji Med. Univ. (1999) 19(3):212-214.
    • (1999) J. Tongji Med. Univ. , vol.19 , Issue.3 , pp. 212-214
    • Gao, Y.1    Luo, L.2    He, F.3
  • 59
    • 0033813717 scopus 로고    scopus 로고
    • Abilit of recombinant human TNF binding protein-1 (r-hTBP-1) to inhibit the development of experimentally-induced endometriosis in rats
    • D'ANTONIO M, MARTELLI F, PEANO S, PAPOIAN R, BORRELLI F: Abilit of recombinant human TNF binding protein-1 (r-hTBP-1) to inhibit the development of experimentally-induced endometriosis in rats. J. Reprod. Immunol. (2000) 48:81-98.
    • (2000) J. Reprod. Immunol. , vol.48 , pp. 81-98
    • D'antonio, M.1    Martelli, F.2    Peano, S.3    Papoian, R.4    Borrelli, F.5
  • 60
    • 1542723183 scopus 로고    scopus 로고
    • Efficacy of anti-tumor necrosis factor therapy in the treatment of spontaneous endometriosis baboons
    • BARRIER BE, BATES GW, LELAND MM, LEACH DA, ROBINSON RD, PROPST AM: Efficacy of anti-tumor necrosis factor therapy in the treatment of spontaneous endometriosis baboons. Fertil. Steril. (2004) 81(Suppl. 1):775-779.
    • (2004) Fertil. Steril. , vol.81 , Issue.SUPPL. 1 , pp. 775-779
    • Barrier, B.E.1    Bates, G.W.2    Leland, M.M.3    Leach, D.A.4    Robinson, R.D.5    Propst, A.M.6
  • 61
    • 0002092687 scopus 로고    scopus 로고
    • Recombinant human TNF binding protein-1 (r-hTBP-1) inhibits the development of endometriosis in baboons; a prospective, randomized, placebo and drug controlled study
    • D'HOOGHE TM, NUGENT NP, CUNEO S et al.: Recombinant human TNF binding protein-1 (r-hTBP-1) inhibits the development of endometriosis in baboons; a prospective, randomized, placebo and drug controlled study. Biol. Reprod. (2005):21.
    • (2005) Biol. Reprod. , pp. 2
    • D'Hooghe, T.M.1    Nugent, N.P.2    Cuneo, S.3


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