Treatment of endometriosis and chronic pelvic pain with letrozole and norethindrone acetate: A pilot study

Fertility and Sterility

Volumn 81, Issue 2, 2004, Pages 290-296

  Ailawadi, Radhika K ^a   Jobanputra, Smeeta ^a   Kataria, Meera ^a   Gurates, Bilgin ^a   Bulun, Serdar E ^a,b  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^b NORTHWESTERN UNIVERSITY   (United States)

Author keywords

Aromatase inhibitor; Bone density; DEXA; Endometriosis; Estrogen; Laparoscopy; Letrozole; Norethindrone acetate

Indexed keywords

CITRATE CALCIUM; CONTRACEPTIVE AGENT; DANAZOL; ESTRONE; FOLLITROPIN; GONADOTROPIN; LETROZOLE; LEUPRORELIN; LUTEINIZING HORMONE; NORETHISTERONE; VITAMIN D;

ADULT; ARTICLE; BONE BIOPSY; BONE DENSITY; BONE SCINTISCANNING; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG DOSE REGIMEN; ENDOMETRIOSIS; ENDOMETRIUM ABLATION; ENDOMETRIUM BIOPSY; ESTRONE BLOOD LEVEL; FEMALE; FOLLITROPIN BLOOD LEVEL; GONADOTROPIN BLOOD LEVEL; HISTOLOGY; HUMAN; LAPAROSCOPY; LUTEINIZING HORMONE BLOOD LEVEL; NEURECTOMY; OUTPATIENT; PAIN ASSESSMENT; PELVIS PAIN SYNDROME; PHASE 2 CLINICAL TRIAL; PRIORITY JOURNAL; VISUAL ANALOG SCALE; VITAMIN SUPPLEMENTATION;

EID: 1242306539     PISSN: 00150282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fertnstert.2003.09.029     Document Type: Article

References (22)

1. Littman B.A., Smotrich D.B., Stillman R.J. Endometriosis. Becker K.L. Principles and practice of endocrinology and metabolism. 2d ed. 1995;906-909 J.B. Lippincott Company, Philadelphia.
2. Surrey E.S., Hornstein M.D. Prolonged GnRH agonist and add-back therapy for symptomatic endometriosis long-term follow-up . Obstet Gynecol. 99:2002;709-709.
3. Pierce S.J., Gazvani M.R., Farquharson R.G. Long-term use of gonadotropin-releasing hormone analogs and hormone replacement therapy in the management of endometriosis a randomized trial with a 6-year follow-up . Fertil Steril. 74:2000;964-968.
4. Franke H.R., van de Weijer P.H., Pennings T.M., van der Mooren M.J. Gonadotropin-releasing hormone agonist plus "add-back" hormone replacement therapy for treatment of endometriosis a prospective, randomized, placebo-controlled, double-blind trial . Fertil Steril. 74:2000;534-539.
5. Vercellini P., Cortesi I., Crosignani P. Progestins for symptomatic endometriosis a critical analysis of the evidence . Fertil Steril. 68:1997;393-401.
6. Farquhar C., Sutton C. The evidence for the management of endometriosis. Curr Opin Obstet Gynecol. 10:1998;321-332.
7. Zeitoun K.M., Bulun S.E. Aromatase a key molecule in the pathophysiology of endometriosis and a therapeutic target . Fertil Steril. 72:1999;961-969.
8. Bulun S.E., Zeitoun K., Takayama K., Noble L., Michael D., Simpson E., et al. Estrogen production in endometriosis and use of aromatase inhibitors to treat endometriosis. Endo Rel Cancer. 6:1999;293-301.
9. Meinhardt U., Mullis P.E. The essential role of the aromatase/p450arom. Semin Reprod Med. 20:2002;277-284.
10. Goss P.E., Strasser K. Aromatase inhibitors in the treatment and prevention of breast cancer. J Clin Oncol. 19:2001;881-894.
11. Takayama K., Zeitoun K., Gunby R.T., Sasano H., Carr B.R., Bulun S.E. Treatment of severe postmenopausal endometriosis with an aromatase inhibitor. Fertil Steril. 69:1998;709-713.
12. Revised American Society for Reproductive Medicine classification of endometriosis 1996 . Fertil Steril. 67:1997;817-821.
13. Lin S.Y., Lee R.K., Hwu Y.M., Lin M.H. Reproducibility of the revised American Fertility Society classification of endometriosis using laparoscopy or laparotomy. Int J Gynaecol Obstet. 60:1998;265-269.
14. Abbott J.A., Hawe J., Clayton R.D., Garry R. The effects and effectiveness of laparoscopic excision of endometriosis a prospective study with 2-5 year follow-up . Hum Reprod. 18:2003;1922-1927.
15. Cosson M., Querleu D., Donnez J., Madelenat P., Konincks P., Audebert A., et al. Dienogest is as effective as triptorelin in the treatment of endometriosis after laparoscopic surgery results of a prospective, multicenter, randomized study . Fertil Steril. 77:2002;684-692.
16. Barcz E., Kaminski P., Marianowski L. Role of cytokines in pathogenesis of endometriosis. Med Sci Monit. 6:2000;1042-1046.
17. Sidell N., Han S.W., Parthasarathy S. Regulation and modulation of abnormal immune responses in endometriosis. Ann NY Acad Sci. 955:2002;159-173.
18. Lebovic D.I., Mueller M.D., Taylor R.N. Immunobiology of endometriosis. Fertil Steril. 75:2001;1-10.
19. Muneyyirci-Delale O., Karacan M. Effect of norethindrone acetate in the treatment of symptomatic endometriosis. Int J Fertil Womens Med. 43:1998;24-27.
20. Aygestin prescribing information. Physicians' desk reference, 57th ed. Montvale, N.J.: Thomson PDR, 2003.
21. Mitwally M.F., Casper R.F. Use of an aromatase inhibitor for induction of ovulation in patients with an inadequate response to clomiphene citrate. Fertil Steril. 75:2001;305-309.
22. Mitwally M.F., Casper R.F. Aromatase inhibitors for the treatment of infertility. Expert Opin Investig Drugs. 12:2003;353-371.