Expression of pigment epithelium-derived factor and vascular endothelial growth factor in fibrovascular membranes from patients with proliferative diabetic retinopathy

Japanese Journal of Ophthalmology

Volumn 50, Issue 2, 2006, Pages 116-120

  Matsuoka, Masato ^a   Ogata, Nahoko ^a   Minamino, Keizo ^a   Matsumura, Miyo ^a  

^a KANSAI MEDICAL UNIVERSITY   (Japan)

Author keywords

Diabetic mellitus; Diabetic retinopathy; Pigment epithelium derived factor; Proliferative diabetic retinopathy; Vascular endothelial growth factor

Indexed keywords

PIGMENT EPITHELIUM DERIVED FACTOR; VASCULOTROPIN;

ADULT; ANGIOGENESIS; ARTICLE; CLINICAL ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; DIABETIC PATIENT; DIABETIC RETINOPATHY; ENDOTHELIUM CELL; EXTRACELLULAR MATRIX; EYE; FEMALE; FIBER; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MALE; MEMBRANE; MODULATION; OCULAR BLOOD VESSEL; PRIORITY JOURNAL; PROTEIN EXPRESSION; TISSUE; VITRECTOMY;

ADULT; BIOLOGICAL MARKERS; DIABETIC RETINOPATHY; EYE PROTEINS; FEMALE; FIBROSIS; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MEMBRANES; MIDDLE AGED; NERVE GROWTH FACTORS; RETINAL NEOVASCULARIZATION; SERPINS; SEVERITY OF ILLNESS INDEX; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 33645704228     PISSN: 00215155     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10384-005-0294-9     Document Type: Article

References (15)

1. AP Adamis JW Miller MT Bernal 1994 Increased vascular endothelial growth factor levels in the vitreous of eyes with proliferative diabetic retinopathy Am J Ophthalmol 118 445 450
2. LP Aiello RL Avery PG Arrigg 1994 Vascular endothelial growth factor in ocular fluid of patients with proliferative diabetic retinopathy and ocular retinal disorders N Engl J Med 331 1480 1487
3. YS Chen SF Hackett CL Scholenfeld MA Vinores SA Vinores PA Campochiaro 1997 Localization of vascular endothelial growth factor and its receptors to cells of vascular and avascular epiretinal membranes Br J Ophthalmol 81 919 926
4. M Boulton D Foreman G Williams D Mcleod 1998 VEGF localization in diabetic retinopathy Br J Ophthalmol 82 562 568
5. DW Dawson OV Volpert P Gillis 1999 Pigment epithelium-derived factor: a potent inhibitor of angiogenesis Science 285 245 248
6. J Spranger M Osterhoff M Reimann 2001 Loss of antiangiogenic pigment epithelium-derived factor in patients with angiogenic eye diseases Diabetes 50 2641 2645
7. N Ogata J Tombran-Tink M Nishikawa 2001 Pigment epithelium derived factor in the vitreous is low in diabetic retinopathy and high in rhegmatogenous retinal detachment Am J Ophthalmol 132 378 382
8. N Ogata M Nishikawa T Nishimura Y Mitsuma M Matsumura 2002 Unbalanced vitreous levels of pigment epithelium-derived factor and vascular endothelial growth factor in diabetic retinopathy Am J Ophthalmol 134 348 353
9. G Gao Y Li D Zhang S Gee C Crosson J-X Ma 2001 Unbalanced expression of VEGF and PEDF in ischemia-induced retinal neovascularizarion FEBS Lett 489 270 276
10. SY Kim C Mocanu DS Mcleod 2003 Expression of pigment epithelium-derived factor (PEDF) and vascular endothelial growth factor (VEGF) in sickle cell retina and choroids Exp Eye Res 77 433 445
11. N Ogata M Wada T Otsuji N Jo J Tombran-Tink M Matsumura 2002 Expression of pigment epithelium-derived factor in normal adult rat eye and experimental choroidal neovascularization Invest Ophthalmol Vis Sci 43 1168 1175
12. M Matsuoka N Ogata T Otsuji T Nishimura K Takahashi M Matsumura 2004 Expression of pigment epithelium-derived factor and vascular endothelial growth factor in choroidal neovascular membranes and polypoidal choroidal vasculopathy Br J Ophthalmol 88 809 815
13. EJ Duh HS Yang I Suzuma 2002 Pigment epithelium-derived factor suppresses ischemia-induced retinal neovascularization and VEGF-induced migration and growth Invest Ophthalmol Vis Sci 43 821 829
14. E Alberdi CC Hyde SP Becerra 1998 Pigment epithelium-derived factor (PEDF) binds to glycosaminoglycans: analysis of the binding site Biochemistry 37 10643 10652
15. N Yasui T Mori O Morito 2003 Dual-site recognition of different extracellular matrix components by anti-angiogenic/neurotrophic serpin, PEDF Biochemistry 42 3160 3167