Expression of pigment epithelium derived factor and vascular endothelial growth factor in choroidal neovascular neovascular membranes and polypoidal choroidal vasculopathy

British Journal of Ophthalmology

Volumn 88, Issue 6, 2004, Pages 809-815

  Matsuoka, M ^a   Ogata, N ^a   Otsuji, T ^a   Nishimura, T ^a   Takahashi, K ^a   Matsumura, M ^a  

^a KANSAI MEDICAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

PIGMENT EPITHELIUM DERIVED FACTOR; VASCULOTROPIN;

ADULT; AGED; ANGIOGENESIS; ARTICLE; CHOROID DISEASE; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE ASSOCIATION; DISEASE COURSE; ENDOTHELIUM CELL; FEMALE; FIBROSIS; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MALE; POLYPOIDAL CHOROIDAL VASCULOPATHY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RETINA MACULA AGE RELATED DEGENERATION; VASCULAR DISEASE; VASCULAR ENDOTHELIUM;

AGED; AGED, 80 AND OVER; CHOROID; CHOROID DISEASES; CHOROIDAL NEOVASCULARIZATION; EYE PROTEINS; FEMALE; FUNDUS OCULI; HISTOCYTOCHEMISTRY; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE AGED; NERVE GROWTH FACTORS; PROTEINS; SERPINS; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 2642566913     PISSN: 00071161     EISSN: None     Source Type: Journal    
DOI: 10.1136/bjo.2003.032466     Document Type: Article

References (42)

1. Green WR, Key SD. Senile macular degeneration: a histopathologic study. Trans Am Ophthalmol Soc 1977;75:180-254.
2. Green WR, McDonnell PJ, Yeo JH. Pathologic features of senile macular degeneration. Ophthalmology 1985;92:615-27.
3. D'Amore PA. Mechanisms of retinal and choroidal neovascularization. Invest Ophthalmol Vis Sci 1994;35:3974-79.
4. Heriot WJ, Henkind P, Bellhorn RW, et al. Choroidal neovascularization can digest Bruch's membrane: a prior break is not essential. Ophthalmology 1984;91:1603-8.
5. Kvanta A, Algvere PV, Berglin L, et al. Subfoveal fibrovascular membranes in age-related macular degeneration express vascular endothelial growth factor. Invest Ophthalmol Vis Sci 1996;37:1929-34.
6. Reddy VM, Zamore RL, Kaplan HJ. Distribution of growth factors in subfoveal fibrovascular membranes in age-related macular degeneration and presumed ocular histoplasmosis syndrome. Am J Ophthalmol 1995;120:291-301.
7. Amin R, Puklin JE, Frank RN. Growth factor localization in choroidal neovascular membranes of age-related macular degeneration. Invest Ophthalmol Vis Sci 1994;35:3178-88.
8. Lopez PF, Sippy BD, Lamber HM, et al. Transdifferentiated retinal pigment epithelial cells are immunoreactive for vascular endothelial growth factor in surgically excised age-related macular degeneration-related choroidal neovascular menbranes. Invest Ophthalmol Vis Sci 1996;37:855-68.
9. Yi X, Ogata N, Komada M, et al. Vascular endothelial growth factor expression in choroidal neavascularization in rats. Graefes Arch Clin Exp Ophthalmol 1997;235:313-19.
10. Wada M, Ogata N, Otsuji T, et al. Expression of vascular endothelial growth factor and its receptor (KDR/flk-1) mRNA in experimental choroidal neovascularization. Curr Eye Res 1999;18:201-13.
11. Ogata N, Yamamoto C, Miyashiro M, et al. Expression of transforming growth factor-β mRNA in experimental choroidal neovascularizarion. Curr Eye Res 1997;16:9-18.
12. Amin RH, Frank RN, Eliot D, et al. Vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF) immunoreactivity in human choroidal neovascular membranes. Invest Opthalmol Vis Sci 1995;36:S2565.
13. Ogata N, Matsushima M, Takada Y, et al. Expression of basic fibroblast growth factor mRNA in developing choroidal neovascularization. Curr Eye Res 1996;15:1008-18.
14. Matsushima M, Ogata N, Takada Y, et al. Expression of fibroblast growth factor receptor 1 in experimental choroidal neovascularization with in situ hybridization. Jpn J Ophthalmol 1996;40:329-38.
15. Frank RN, Amin RH, Eliott D, et al. Basic fibroblast growth factor and vascular endothelial growth factor are present in epiretinal and choroidal neovascular membranes. Am J Ophthalmol 1996;122:393-403.
16. Yannuzzi LA. Idiopothic popypoidal choroidal vasculopathy. Presented at the 1982 Macula Society meeting.
17. Yannuzzi LA, Sorenson J, Spaide RF, et al. Idiopathic popypoidal choroidal vasculopathy (IPCV). Retina 1990;10:1-8.
18. Yannuzzi LA, Wong DW, Sforzolini BS, et al. Popypoidal choroidal vasculopathy and neovascularized age-related macular degeneration. Arch Ophthalmol 1999; 117:1503-10.
19. Uyama M, Matsubara T, Fukuchima I, et al. Idiopathic polypoidal choroidal vasculopathy in Japanese patients. Arch Ophthalmol 1999;117:1035-42.
20. Okubo A, Sameshima M, Uemura A, et al. Clinicopathological correlation of polypoidal choroidal vasculopathy revealed by ultrastructual study. Br J Ophthalmol 2002;86:1093-8.
21. Terasaki H, Miyake Y, Nakamura M, et al. Popypoidal choroidal vasculopathy treated with macular translocation: clinical pathological correlation. Br J Ophthalmol 2002;86:321-7.
22. Bouck N. Tumor angiogenesis: the role of oncogenes and tumor suppressor genes. Cancer Cells 1990;2:179-85.
23. Hanahan D, Folkman Y. Patterns and emerging mechanisms of angiogenic switch during tunorigenesis. Cell 1996;86:353-64.
24. Folkman J. Clinical applications of research on angiogenesis. N Engl J Med 1995;333:1757-63.
25. Dawson DW, Volpert OV, Gillis P, et al. Pigment epithelium-derived factor: a potent inhibitor of angiogenesis. Science 1999;285:245-8.
26. Stellmach V, Crawford SE, Zhou W, et al. Prevention of ischemia-induced retinopathy by the natural ocular antiangiogenic agent pigment epithelium-derived factor. Proc Natl Acad Soc USA 2001;98:2593-7.
27. Ogata N, Wada M, Otsuji T, et al. Expression of pigment epithelium-derived factor in normal adult rat eye and experimental choroidal neovascularization. Invest Ophthalmol Vis Sci 2002;43:1168-75.
28. Lambert HM, Capone A Jr, Aaberg TM, et al. Surgical excision of subfoveal neovascular membranes in age-related macular degeneration. Am J Ophthalmol 1992;113:257-62.
29. Ogata N, Tombran-Tink J, Nishikawa M, et al. Pigment epithelium-derived factor in the vitreous is low in diabetic retinopathy and high in rhegmatogenous retinal detachment. Am J Ophthalmol 2001;132:378-82.
30. Ogata N, Nishikawa M, Nishimura T, et al. Unbalanced vitreous levels of pigment epithelium-derived factor and vascular endothelial growth factor in diabetic retinopathy. Am J Ophthalmol 2002;134:348-53.
31. Gao G, Li Y, Zhang D, et al. Unbalanced expression of VEGF and PEDF in ischemia-induced retinal neovascularizarion. FEBS Lett 2001;489:270-6.
32. Duh EJ, Yang HS, Suzuma I, et al. Pigment epithelium-derived factor suppresses ischemia-induced retinal neovascularization and VEGF-induced migration and growth. Invest Ophthalmol Vis Sci 2002;43:821-9.
33. Gao G, Li Y, Gee S, et al. Down-regulation of VEGF and up-regulation of PEDF: a possible mechanism for the anti-angiogenic activity of plasminogen kringle 5. J Biol Chem 2002;277:9492-7.
34. Miyagishi D, Ohno MK, Amagasa T, et al. Regulation of the expression of pigment epithelium-derived factor in human oral squamous cell cartinoma cell line. Cancer Lett 2003;196:77-85.
35. Renno RZ, Youssri AI, Michaud N, et al. Expression of pigment epithelium-derived factor in experimental choroidal neovascularization. Invest Ophthalmol Vis Sci 2002;43:1574-80.
36. Holekamp NM, Bouck N, Volpert O. Pigment epithelium-derived factor is deficient in the vitreous of patients with choroidal neovascularization due to age-related macular degeneration (1). Am J Ophthalmol 2002;134:220-7.
37. Ogata N, Nishikawa M, Nishimura T, et al. Inverse levels of pigment epithelium-derived factor and vascular endothelial growth factor in the vitreous of eyes with rhegmatogenous retinal detachment and proliferative vitreoretinopathy. Am J Ophthalmol 2002;133:851-2.
38. Ohono-Matsui K, Morita I, Tombran-Tink J, et al. Novel mechanism for age-related macular degeneration: an equilibrium shift between the angiogenesis factors VEGF and PEDF. J Cell Physiol 2001;189:323-33.
39. Ohono-Matsui K, Yoshida T, et al. Vascular endothelial growth factor upregulates pigment epithelium-derived factor expression via VEGFR-1 in human retinal pigment epithelial cells. Biochem Biophy Res Comm 2003;303:962-7.
40. Adamis AP, Shima DT, Yeo KT, et al. Synthesis and secretion of vascular permeability factor/vascular endothelial growth factor by human retinal pigment epithelial cells. Biochem Biophys Res Comm 1993;193:631-8.
41. Yi X, Mai LC, Uyama M, et al. Time-course expression of vascular endothelial growth factor as related to the development of the retinochoroidal vasculature in rats. Exp Brain Res 1998;193:155-60.
42. Ogata N, Yamanaka R, Yamamoto C, et al. Expression of vascular endothelial growth factor and its receptor, KDR, following retinal ischemia-reperfusion injury in the rat. Curr Eye Res 1998;17:1087-96.