Epidermal growth factor-regulated activation of Rac GTPase enhances CD44 cleavage by metalloproteinase disintegrin ADAM10

Biochemical Journal

Volumn 395, Issue 1, 2006, Pages 65-71

  Murai, Toshiyuki ^a   Miyauchi, Takayuki ^b   Yanagida, Toshio ^b   Sako, Yasushi ^b  

^a OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b OSAKA UNIVERSITY   (Japan)

Author keywords

A disintegrin and metalloproteinase (ADAM); CD44; Cell surface adhesion molecule; Epidermal growth factor (EGF); Rac GTPase; Shedding

Indexed keywords

ACTIVATION ENERGY; CELLS; EPIDEMIOLOGY; GROWTH KINETICS; RNA; TUMORS;

A DISINTEGRIN AND METALLOPROTEINASE (ADAM); CD44; CELL-SURFACE ADHESION MOLECULE; EPIDERMAL GROWTH FACTOR (EGF); RAC GTPASE; SHEDDING;

ENZYMES;

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; A DISINTEGRIN AND METALLOPROTEINASE 10; CELL ADHESION MOLECULE; DISINTEGRIN; EPIDERMAL GROWTH FACTOR; GUANOSINE TRIPHOSPHATASE; HERMES ANTIGEN; METALLOPROTEINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; RAC GUANOSINE TRIPHOSPHATASE; RAC PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CANCER CELL; CANCER INVASION; CELL MIGRATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; GLIOMA; HUMAN; HUMAN CELL; METASTASIS; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; RNA INTERFERENCE;

ADAM PROTEINS; AMYLOID PRECURSOR PROTEIN SECRETASES; ANTIGENS, CD44; CELL LINE, TUMOR; CELL MOVEMENT; CELL SURFACE EXTENSIONS; DISINTEGRINS; ENZYME ACTIVATION; EPIDERMAL GROWTH FACTOR; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HUMANS; MEMBRANE PROTEINS; MITOGEN-ACTIVATED PROTEIN KINASES; PSEUDOPODIA; RAC1 GTP-BINDING PROTEIN; TUMOR CELLS, CULTURED;

EID: 33645575688     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20050582     Document Type: Article

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