Ab-induced ectodomain shedding mediates hepatocytes growth factor receptor down-regulation and hampers biological activity

Proceedings of the National Academy of Sciences of the United States of America

Volumn 103, Issue 13, 2006, Pages 5090-5095

  Petrelli, Annalisa ^a   Circosta, Paola ^a   Granziero, Luisa ^a   Mazzone, Massimiliano ^a   Pisacane, Alberto ^a   Fenoglio, Silvia ^a   Comoglio, Paolo M ^a,b   Giordano, Silvia ^a,b  

^a UNIVERSITY OF TURIN   (Italy)

^b CANDIOLO CANCER INSTITUTE   (Italy)

Author keywords

Ab; Metastasis; Proteolytic cleavage; Receptor degradation; Tyrosine kinase

Indexed keywords

ANTIBODY; BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; CONCANAMYCIN A; LACTACYSTIN; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY DN30; PROTEASOME; SCATTER FACTOR RECEPTOR; TYROSINE KINASE RECEPTOR; UNCLASSIFIED DRUG;

ANCHORAGE INDEPENDENT GROWTH; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIOLOGICAL ACTIVITY; CANCER INVASION; CANCER THERAPY; CANCER TRANSPLANTATION; CARCINOMA CELL; CONTROLLED STUDY; DRUG MECHANISM; FEMALE; HUMAN; HUMAN CELL; LUNG; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; RECEPTOR DOWN REGULATION; SIGNAL TRANSDUCTION; TUMOR CELL;

ANIMALS; ANTIBODIES, MONOCLONAL; CELL LINE, TUMOR; CELL PROLIFERATION; CELL TRANSFORMATION, NEOPLASTIC; DISEASE PROGRESSION; DOWN-REGULATION; FEMALE; HUMANS; MICE; NEOPLASMS; PHENOTYPE; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTO-ONCOGENE PROTEINS C-MET; SIGNAL TRANSDUCTION;

ANIMALIA;

EID: 33645518840     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0508156103     Document Type: Article

References (48)

1. Hudson, P. J. (1999) Curr. Opin. Immunol. 11, 548-557.
2. Hudson, P. J. & Souriau, C. (2003) Nat. Med. 9, 129-134.
3. Gschwind, A., Fischer, O. M. & Ullrich, A. (2004) Nat. Rev. Cancer 4, 361-370.
4. Cragg, M. S., French, R. R. & Glennie, M. J. (1999) Curr. Opin. Immunol. 11, 541-547.
5. Ferrara, N., Hillan, K. J., Gerber, H. P. & Novotny, W. (2004) Nat. Rev. Drug Discovery 3, 391-400.
6. Li, S., Schmitz, K. R., Jeffrey, P. D., Wiltzius, J. J., Kussie, P. & Ferguson, K. M. (2005) Cancer Cell 7, 301-311.
7. Hynes, N. E. & Lane, H. A. (2005) Nat. Rev. Cancer 5, 341-354.
8. Trusolino, L. & Comoglio, P. M. (2002) Nat. Rev. Cancer 2, 289-300.
9. Schmidt, L., Duh, F. M., Chen, F., Kishida, T., Glenn, G., Choyke, P., Scherer, S. W., Zhuang, Z., Lubensky, I., Dean, M., et al. (1997) Nat. Genet. 16, 68-73.
10. Kim, I. J., Park, J. H., Kang, H. C., Shin, Y., Lim, S. B., Ku, J. L., Yang, H. K., Lee, K. U. & Park, J. G. (2003) J. Med. Genet. 40, e97.
11. Di Renzo, M. F., Olivero, M., Giacomini, A., Porte, H., Chastre, E., Mirossay, L., Nordlinger, B., Bretti, S., Bottardi, S., Giordano, S., et al. (1995) Clin. Cancer Res. 1, 147-154.
12. Corso, S., Comoglio, P. M. & Giordano, S. (2005) Trends Mol. Med. 11, 284-292.
13. Prat, M., Crepaldi, T., Pennacchietti, S., Bussolino, F. & Comoglio, P. M. (1998) J. Cell Sci. 111, 237-247.
14. Giordano, S., Ponzetto, C., Di Renzo, M. F., Cooper, C. S. & Comoglio, P. M. (1989) Nature 339, 155-156.
15. Frisch, S. M. & Francis, H. (1994) J. Cell Biol. 124, 619-626.
16. Zeng, Q., Chen, S., You, Z., Yang, F., Carey, T. E., Saims, D. & Wang, C. Y. (2002) J. Biol. Chem. 277, 25203-25208.
17. Qiao, H., Hung, W., Tremblay, E., Wojcik, J., Gui, J., Ho, J., Klassen, J., Campling, B. & Elliott, B. (2002) J. Cell. Biochem. 86, 665-677.
18. Qiao, H., Saulnier, R., Patryzkat, A., Rahimi, N., Raptis, L., Rossiter, J., Tremblay, E. & Elliott, B. (2000) Cell Growth Differ. 11, 123-133.
19. Trusolino, L., Bertotti, A. & Comoglio, P. M. (2001) Cell 107, 643-654.
20. Bussolino, F., Di Renzo, M. F., Ziche, M., Bocchietto, E., Olivero, M., Naldini, L., Gaudino, G., Tamagnone, L., Coffer, A. & Comoglio, P. M. (1992) J. Cell Biol. 119, 629-641.
21. Sengupta, S., Gherardi, E., Sellers, L. A., Wood, J. M., Sasisekharan, R. & Fan, T. P. (2003) Arterioscler. Thromb. Vasc. Biol. 23, 69-75.
22. Worden, B., Yang, X. P., Lee, T. L., Bagain, L., Yeh, N. T., Cohen, J. G., Van, W. C. & Chen, Z. (2005) Cancer Res. 65, 7071-7080.
23. Zhang, Y. W., Su, Y., Volpert, O. V. & Vande Woude, G. F. (2003) Proc. Natl. Acad. Sci. USA 100, 12718-12723.
24. Waterman, H. & Yarden, Y. (2001) FEBS Lett. 490, 142-152.
25. Arribas, J. & Borroto, A. (2002) Chem. Rev. 102, 4627-4638.
26. Jeffers, M., Taylor, G. A., Weidner, K. M., Omura, S. & Vande Woude, G. F. (1997) Mol. Cell. Biol. 17, 799-808.
27. Prat, M., Crepaldi, T., Gandino, L., Giordano, S., Longati, P. & Comoglio, P. (1991) Mol. Cell. Biol. 11, 5954-5962.
28. Petrelli, A., Gilestro, G. F., Lanzardo, S., Comoglio, P. M., Migone, N. & Giordano, S. (2002) Nature 416, 187-190.
29. Peschard, P., Fournier, T. M., Lamorte, L., Naujokas, M. A., Band, H., Langdon, W. Y. & Park, M. (2001) Mol. Cell 8, 995-1004.
30. Ponzetto, C., Bardelli, A., Zhen, Z., Maina, F., Dalla, Z. P., Giordano, S., Graziani, A., Panayotou, G. & Comoglio, P. M. (1994) Cell 77, 261-271.
31. Giordano, S., Corso, S., Conrotto, P., Artigiani, S., Gilestro, G., Barberis, D., Tamagnone, L. & Comoglio, P. M. (2002) Nat. Cell Biol. 4, 720-724.
32. Michieli, P., Mazzone, M., Basilico, C., Cavassa, S., Sottile, A., Naldini, L. & Comoglio, P. M. (2004) Cancer Cell 6, 61-73.
33. Birchmeier, C., Birchmeier, W., Gherardi, E. & Vande Woude, G. F. (2003) Nat. Rev. Mol. Cell Biol. 4, 915-925.
34. Maulik, G., Shrikhande, A., Kijima, T., Ma, P. C., Morrison, P. T. & Salgia, R. (2002) Cytokine Growth Factor Rev. 13, 41-59.
35. Kong-Beltran, M., Stamos, J. & Wickramasinghe, D. (2004) Cancer Cell 6, 75-84.
36. Ivan, M., Bond, J. A., Prat, M., Comoglio, P. M. & Wynford-Thomas, D. (1997) Oncogene 14, 2417-2423.
37. Gambarotta, G., Boccaccio, C., Giordano, S., Ando, M., Stella, M. C. & Comoglio, P. M. (1996) Oncogene 13, 1911-1917.
38. Furge, K. A., Kiewlich, D., Le, P., Vo, M. N., Faure, M., Hewlett, A. R., Lipson, K. E., Woude, G. F. & Webb, C. P. (2001) Proc. Natl. Acad. Sci. USA 98, 10722-10727.
39. Sariola, H. & Saarma, M. (2003) J. Cell Sci. 116, 3855-3862.
40. Pennacchietti, S., Michieli, P., Galluzzo, M., Mazzone, M., Giordano, S. & Comoglio, P. M. (2003) Cancer Cell 3, 347-361.
41. Morotti, A., Mila, S., Accornero, P., Tagliabue, E. & Ponzetto, C. (2002) Oncogene 21, 4885-4893.
42. Christensen, J. G., Schreck, R., Burrows, J., Kuruganti, P., Chan, E., Le, P., Chen, J., Wang, X., Ruslim, L., Blake, R., et al. (2003) Cancer Res. 63, 7345-7355.
43. Berthou, S., Aebersold, D. M., Schmidt, L. S., Stroka, D., Heigl, C., Streit, B., Stalder, D., Gruber, G., Liang, C., Hewlett, A. R., et al. (2004) Oncogene 23, 5387-5393.
44. Arribas, J., Coodly, L., Vollmer, P., Kishimoto, T. K., Rose-John, S. & Massague, J. (1996) J. Biol. Chem. 271, 11376-11382.
45. Blobel, C. P. (2000) Curr. Opin. Cell Biol. 12, 606-612.
46. Di Fiore, P. P. & De, C. P. (2001) Cell 106, 1-4.
47. Sorkin, A. & Von, Z. M. (2002) Nat. Rev. Mol. Cell Biol. 3, 600-614.
48. Schaeffer, W. I. & Friend, K. (1976) Cancer Lett. 1, 259-262.