Determination of acid-base dissociation constants of amino- and guanidinopurine nucleotide analogs and related compounds by capillary zone electrophoresis

Electrophoresis

Volumn 27, Issue 5-6, 2006, Pages 1006-1019

  Šolínová, Veronika ^a   Kašička, Václav ^a   Koval, Dušan ^a   Česnek, Michal ^a   Holý, Antonín ^a  

^a INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY   (Czech Republic)

Author keywords

Acyclic nucleoside phosphonates; Aminopurine nucleosides; Capillary electrophoresis; Dissociation constant (pKa); Guanidinopurine nucleosides

Indexed keywords

DISSOCIATION; ELECTROPHORETIC MOBILITY; IONIC STRENGTH; NITROGEN; NUCLEOTIDES; ORGANIC ACIDS; PROTONATION; REGRESSION ANALYSIS;

ACID BASE; ACYCLIC NUCLEOSIDE PHOSPHONATE; AMINOPURINE; AMINOPURINE NUCLEOSIDE; DISSOCIATION CONSTANT; DISSOCIATION CONSTANT (PKA); GUANIDINOPURINE NUCLEOSIDE; NUCLEOTIDE ANALOGUES; PHOSPHONATES; RELATED COMPOUNDS;

CAPILLARY ELECTROPHORESIS;

2 AMINO 6 GUANIDINO 9 ISOPROPYL 9H PURINE; 2 AMINO 6 GUANIDINO 9 [2 (PHOSPHONOMETHOXY)ETHYL] 9H PURINE; 2 AMINO 9 [2 (PHOSPHONOMETHOXY)ETHYL] 9H PURINE; 2 GUANIDINO 9 ISOPROPYL 9H PURINE; 2 GUANIDINO 9 [2 (PHOSPHONOMETHOXY)ETHYL] 9H PURINE; 2,6 DIAMINO 9 [2 (PHOSPHONOMETHOXY)ETHYL] 9H PURINE; 6 AMINO 2 GUANIDINE 9 [2 (PHOSPHONOMETHOXY)ETHYL] 9H PURINE; 6 AMINO 2 GUANIDINO 9 ISOPROPYL 9H PURINE; 6 AMINO 9 [2 [(DIISOPROPYLOXY)PHOSPHORYLMETHOXY]ETHYL] 2 GUANIDINO 9H PURINE; 6 GUANIDINO 9 METHYL 9H PURINE; 6 GUANIDINO 9 [2 (PHOSPHONOMETHOXY)ETHYL] 9H PURINE; 9 [2 (PHOSPHONOMETHOXY)ETHYL]GUANINE; 9 [2 [(DIISOPROPYLOXY)PHOSPHORYLMETHOXY]ETHYL] 2 GUANIDINO 9H PURINE; ACYCLIC NUCLEOSIDE; ACYCLIC NUCLEOSIDE PHOSPHONATE; ACYCLIC NUCLEOSIDE PHOSPHONATE DIESTER; AMINOGUANIDINO 9 ALKYLPURINE; AMINOGUANIDINOPURINE NUCLEOTIDE; GUANIDINOPURINE NUCLEOTIDE; NITROGEN; NUCLEOTIDE DERIVATIVE; PHOSPHONIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

ACID BASE BALANCE; ANTIVIRAL ACTIVITY; ARTICLE; CAPILLARY ZONE ELECTROPHORESIS; CONTROLLED STUDY; CYTOSTASIS; DRUG STRUCTURE; DRUG SYNTHESIS; ELECTROPHORETIC MOBILITY; IONIC STRENGTH; NONLINEAR REGRESSION ANALYSIS; PH; PHARMACOPHORE; PROTON TRANSPORT; STRUCTURE ANALYSIS; TEMPERATURE DEPENDENCE;

EID: 33645473124     PISSN: 01730835     EISSN: 15222683     Source Type: Journal    
DOI: 10.1002/elps.200500815     Document Type: Article

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