Molecularly imprinted nanoreactors for regioselective Huisgen 1,3-dipolar cycloaddition reaction

Journal of the American Chemical Society

Volumn 128, Issue 13, 2006, Pages 4178-4179

  Zhang, Huiqi ^a   Piacham, Theeraphon ^a   Drew, Mark ^b   Patek, Marcel ^b   Mosbach, Klaus ^a   Ye, Lei ^a  

^a LUND UNIVERSITY   (Sweden)

^b Aventis Combinatorial Technol Ctr   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALKYNE; AZIDE;

ARTICLE; BIOLOGICAL ACTIVITY; CHEMICAL REACTION KINETICS; CHEMICAL STRUCTURE; CLONING; CYCLOADDITION; DIPOLE; MOLECULAR IMPRINTING; MOLECULAR INTERACTION; NANOPARTICLE; STEREOCHEMISTRY;

ACETYLENE; AZIDES; CYCLIZATION; DRUG DESIGN; NANOSTRUCTURES; POLYMERS;

EID: 33645463533     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja057781u     Document Type: Article

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25. The yield of 3a from the reaction involving MIP(3a) has been corrected by subtracting the template leakage (Supporting Information).
26. An even higher anti-isomer ratio (97%) was observed in the MIP(Sa)-bound product. The polymer-bound product was recovered by methanol: acetic acid wash.