ERK/MAPK regulates the Kv4.2 potassium channel by direct phosphorylation of the pore-forming subunit

American Journal of Physiology - Cell Physiology

Volumn 290, Issue 3, 2006, Pages

  Schrader, Laura A ^a,b   Birnbaum, Shari G ^a   Nadin, Brian M ^a   Ren, Yajun ^a   Bui, Duy ^a   Anderson, Anne E ^a   Sweatt, J David ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b Tulane University   (United States)

Author keywords

A type current; K+ channel interacting protein; Kinase; Neurons

Indexed keywords

ASPARTIC ACID; MITOGEN ACTIVATED PROTEIN KINASE; POTASSIUM CHANNEL; POTASSIUM CHANNEL INTERACTING PROTEIN 3; POTASSIUM CHANNEL KV4.2; SERINE; THREONINE; UNCLASSIFIED DRUG; MITOGEN ACTIVATED PROTEIN KINASE KINASE; PROTEIN SUBUNIT; SHAL POTASSIUM CHANNEL;

ANIMAL CELL; ARTICLE; CHANNEL GATING; CONTROLLED STUDY; ELECTROPHYSIOLOGY; NERVE CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SITE DIRECTED MUTAGENESIS; WILD TYPE; AMINO ACID SUBSTITUTION; ANIMAL; CELL STRAIN COS1; CERCOPITHECUS; CHEMISTRY; GENETICS; METABOLISM; MUTATION; OOCYTE; PHOSPHORYLATION; XENOPUS LAEVIS;

ANIMALIA;

AMINO ACID SUBSTITUTION; ANIMALS; CERCOPITHECUS AETHIOPS; COS CELLS; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; MUTAGENESIS, SITE-DIRECTED; MUTATION; OOCYTES; PHOSPHORYLATION; PROTEIN SUBUNITS; SHAL POTASSIUM CHANNELS; XENOPUS LAEVIS;

EID: 33645460750     PISSN: 03636143     EISSN: 15221563     Source Type: Journal    
DOI: 10.1152/ajpcell.00358.2005     Document Type: Article

References (51)

1. Adams JP, Anderson AE, Varga AW, Dineley KT, Cook RG, Pfaffinger PJ, and Sweatt JD. The A-type potassium channel Kv4.2 is a substrate for the mitogen-activated protein kinase ERK. J Neurochem 75: 2277-2287, 2000.
2. An WF, Bowlby MR, Betty M, Cao J, Ling HP, Mendoza G, Hinson JW, Mattsson KI, Strassle BW, Trimmer JS, and Rhodes KJ. Modulation of A-type potassium channels by a family of calcium sensors. Nature 403: 553-556, 2000.
3. Atkins CM, Selcher JC, Petraitis JJ, Trzaskos JM, and Sweatt JD. The MAPK cascade is required for mammalian associative learning. Nat Neurosci 1: 602-609, 1998.
4. Bahring R, Dannenberg J, Peters HC, Leicher T, Pongs O, and Isbrandt D. Conserved N-terminal Kv4 domain critical for effects of Kv channel-interacting protein 2.2 on channel expression and gating. J Biol Chem 276: 23888-23894, 2001.
5. Beck EJ, Bowlby M, An WF, Rhodes KJ, and Covarrubias M. Remodelling inactivation gating of Kv4 channels by KChIP1, a small-molecular-weight calcium-binding protein. J Physiol 538: 691-706, 2002.
6. + channel. Insights into the molecular mechanism of protein kinase C action. J Gen Physiol 112: 71-84, 1998.
7. Bernard C, Anderson A, Becker A, Poolos NP, Beck H, and Johnston D. Acquired dendritic channelopathy in temporal lobe epilepsy. Science 305: 532-535, 2004.
8. + channel cloned from the rat cardiovascular system. FEBS Lett 295: 211-213, 1991.
9. Bozon B, Kelly A, Josselyn SA, Silva AJ, Davis S, and Laroche S. MAPK, CREB and zif268 are all required for the consolidation of recognition memory. Philos Trans R Soc Lond B Biol Sci 358: 805-814, 2003.
10. Chen Z, Gibson TB, Robinson F, Silvestro L, Pearson G, Xu B, Wright A, Vanderbilt C, and Cobb MH. MAP kinases. Chem Rev 101: 2449-2476, 2001.
11. Covarrubias M, Wei A, Salkoff L, and Vyas TB. Elimination of rapid potassium channel inactivation by phosphorylation of the inactivation gate. Neuron 13: 1403-1412, 1994.
12. Dourado MM and Dryer SE. Regulation of A-currents by cell-cell interactions and neurotrophic factors in developing chick parasympathetic neurones. J Physiol 474: 367-377, 1994.
13. English JD and Sweatt JD. Activation of p42 mitogen-activated protein kinase in hippocampal long term potentiation. J Biol Chem 271: 24329-24332, 1996.
14. English JD and Sweatt JD. A requirement for the mitogen-activated protein kinase cascade in hippocampal long-term potentiation. J Biol Chem 272: 19103-19106, 1997.
15. Frick A, Magee J, and Johnston D. LTP is accompanied by an enhanced local excitability of pyramidal neuron dendrites. Nat Neurosci 7: 126-135, 2004.
16. Gebauer M, Isbrandt D, Sauter K, Callsen B, Nolting A, Pongs O, and Bahring R. N-type inactivation features of Kv4.2 channel gating. Biophys J 86: 210-223, 2004.
17. + currents. Circ Res 90: 586-593, 2002.
18. + currents in the mammalian myocardium by neuronal calcium sensor-1. J Biol Chem 277: 26436-26443, 2002.
19. + current diversity in mouse ventricular myocytes. J Physiol 521: 587-599, 1999.
20. Hakes DJ and Dixon JE. New vectors for high level expression of recombinant proteins in bacteria. Anal Biochem 202: 293-298, 1992.
21. + channels in dendrites of hippocampal CA1 pyramidal neurons by activation of PKA and PKC. J Neurosci 18: 3521-3528, 1998.
22. Hoffman DA and Johnston D. Neurotransmitter modulation of dendritic action potentials. J Neurophysiol 81: 408-411, 1999.
23. + channel regulation of signal propagation in dendrites of hippocampal pyramidal neurons. Nature 387: 869-875, 1997.
24. Holmqvist MH, Cao J, Knoppers MH, Jurman ME, Distefano PS, Rhodes KJ, Xie Y, and An WF. Kinetic modulation of Kv4-mediated A-current by arachidonic acid is dependent on potassium channel interacting proteins. J Neurosci 21: 4154-4161, 2001.
25. + currents. J Neurophysiol 90: 1671-1679, 2003.
26. Jerng HH, Kunjilwar K, and Pfaffinger PJ. Multiprotein assembly of Kv4.2, KChIP3, and DPP10 produces ternary channel complexes with ISA-like properties. J Physiol 568: 767-788, 2005.
27. Jerng HH, Qian Y, and Pfaffinger PJ. Modulation of Kv4.2 channel expression and gating by dipeptidyl peptidase 10 (DPP10). Biophys J 87: 2380-2396, 2004.
28. Lewis TS, Shapiro PS, and Ahn NG. Signal transduction through MAP kinase cascades. Adv Cancer Res 74: 49-139, 1998.
29. + channel polypeptides in rat hippocampal neurons developing in situ and in vitro. J Neurosci 15: 3840-3851, 1995.
30. Martin KC, Michael D, Rose JC, Barad M, Casadio A, Zhu H, and Kandel ER. MAP kinase translocates into the nucleus of the presynaptic cell and is required for long-term facilitation in Aplysia. Neuron 18: 899-912, 1997.
31. + channels. Neuron 37: 449-461, 2003.
32. Rhodes KJ, Carroll KI, Sung MA, Doliveira LC, Monaghan MM, Burke SL, Strassle BW, Buchwalder L, Menegola M, Cao J, An WF, and Trimmer JS. KChIPs and Kv4 α subunits as integral components of A-type potassium channels in mammalian brain. J Neurosci 24: 7903-7915, 2004.
33. Schrader LA, Anderson AE, Mayne A, Pfaffinger PJ, and Sweatt JD. PKA modulation of Kv4.2-encoded A-type potassium channels requires formation of a supramolecular complex. J Neurosci 22: 10123-10133, 2002.
34. Serodio P, Kentros C, and Rudy B. Identification of molecular components of A-type channels activating at subthreshold potentials. J Neurophysiol 72: 1516-1529, 1994.
35. + (A-type) currents in rat brain. J Neurophysiol 79: 1081-1091, 1998.
36. + channels operating at subthreshold potentials with unique expression in heart and brain. J Neurophysiol 75: 2174-2179, 1996.
37. + channel proteins in rat central neurons. Neuron 9: 271-284, 1992.
38. Shibata R, Misonou H, Campomanes CR, Anderson AE, Schrader LA, Doliveira LC, Carroll KI, Sweatt JD, Rhodes KJ, and Trimmer JS. A fundamental role for KChIPs in determining the molecular properties and trafficking of Kv4.2 potassium channels. J Biol Chem 278: 36445-36454, 2003.
39. Song WJ, Tkatch T, Baranauskas G, Ichinohe N, Kitai ST, and Surmeier DJ. Somatodendritic depolarization-activated potassium currents in rat neostriatal cholinergic interneurons are predominantly of the A type and attributable to coexpression of Kv4.2 and Kv4.1 subunits. J Neurosci 18: 3124-3137, 1998.
40. Thomas MJ, Watabe AM, Moody TD, Makhinson M, and O'Dell TJ. Postsynaptic complex spike bursting enables the induction of LTP by theta frequency synaptic stimulation. J Neurosci 18: 7118-7126, 1998.
41. + current amplitude are linearly related in basal ganglia and basal forebrain neurons. J Neurosci 20: 579-588, 2000.
42. + channel α subunit. FEBS Lett 400: 215-220, 1997.
43. + channel mRNAs in the rat brain and downregulation in the hippocampus following seizures. Neuron 8: 1055-1067, 1992.
44. Varga AW, Anderson AE, Adams JP, Vogel H, and Sweatt JD. Input-specific immunolocalization of differentially phosphorylated Kv4.2 in the mouse brain. Learn Mem 7: 321-332, 2000.
45. Varga AW, Yuan LL, Anderson AE, Schrader LA, Wu GY, Gatchel JR, Johnston D, and Sweatt JD. Calcium-calmodulin-dependent kinase II modulates Kv4.2 channel expression and upregulates neuronal A-type potassium currents. J Neurosci 24: 3643-3654, 2004.
46. Watabe AM, Zaki PA, and O'Dell TJ. Coactivation of -adrenergic and cholinergic receptors enhances the induction of long-term potentiation and synergistically activates mitogen-activated protein kinase in the hippocampal CA1 region. J Neurosci 20: 5924-5931, 2000.
47. + channels contribute to spike-timing dependent long-term potentiation in hippocampal pyramidal neurons. Proc Natl Acad Sci USA 99: 8366-8371, 2002.
48. Winder DG, Martin KC, Muzzio IA, Rohrer D, Chruscinski A, Kobilka B, and Kandel ER. ERK plays a regulatory role in induction of LTP by theta frequency stimulation and its modulation by β-adrenergic receptors. Neuron 24: 715-726, 1999.
49. + channels in midbrain dopaminergic neurons. Nat Neurosci 4: 1071-1078, 2001.
50. A in hippocampal CA1 pyramidal neurons. Program No. 810.12. 2003 Abstract Viewer/Itinerary Planner. Washington, DC: Society for Neuroscience, 2003 (online).
51. + channels in hippocampus involves a mitogen-activated protein kinase pathway. J Neurosci 22: 4860-4868, 2002.