Specific sequence motifs direct the oxygenation and chlorination of tryptophan by myeloperoxidase

Biochemistry

Volumn 45, Issue 12, 2006, Pages 3961-3971

  Fu, Xiaoyun ^a   Wang, Yi ^a   Kao, Jeffery ^b   Irwin, Angela ^a   D'Avignon, André ^b   Mecham, Robert P ^b   Parks, William C ^a   Heinecke, Jay W ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; CATALYSIS; CHLORINATION; MASS SPECTROMETRY; NUCLEAR MAGNETIC RESONANCE; OXIDATION;

ACTIVATED NEUTROPHILS; CATALYTIC DOMAIN; PROTEIN OXIDATION; TANDEM MASS SPECTROMETRY;

PROTEINS;

ALANINE; AMIDE; AMINO ACID; CHLOROINDOLENINE DERIVATIVE; GLYCINE; HYPOCHLOROUS ACID; INDOLE; INDOLE DERIVATIVE; MATRILYSIN; MYELOPEROXIDASE; PEPTIDE LIBRARY; THREONINE; TRYPTOPHAN; UNCLASSIFIED DRUG; VALINE;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARTICLE; CHLORINATION; ELECTROSPRAY MASS SPECTROMETRY; ENZYME ACTIVITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; LIQUID CHROMATOGRAPHY; NEUTROPHIL; OXIDATION; OXYGENATION; PRIORITY JOURNAL; PROTEIN CROSS LINKING; PROTON NUCLEAR MAGNETIC RESONANCE; SEQUENCE ANALYSIS; TANDEM MASS SPECTROMETRY;

AMINO ACID MOTIFS; CHLORINE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HUMANS; HYDROGEN PEROXIDE; MASS SPECTROMETRY; OXYGEN; PEROXIDASE; SPECTROPHOTOMETRY, ULTRAVIOLET; TRYPTOPHAN;

EID: 33645449729     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi052339+     Document Type: Article

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