Pharmacokinetics of oltipraz in rat models of diabetes mellitus induced by alloxan or streptozotocin

Life Sciences

Volumn 78, Issue 20, 2006, Pages 2287-2294

  Bae, Soo Kyung ^a   Kim, Ji Young ^a   Yang, Si Hyung ^a   Kim, Jin Wan ^b   Kim, Taekrho ^b   Lee, Myung Gull ^a  

^a Seoul National University   (South Korea)

^b CJ Corporation   (South Korea)

Author keywords

Alloxan or streptozotocin; Diabetes mellitus; Oltipraz; Pharmacokinetics; Rats

Indexed keywords

ALLOXAN; CYTOCHROME P450 1A1; CYTOCHROME P450 1A2; CYTOCHROME P450 2B1; CYTOCHROME P450 2B2; CYTOCHROME P450 2C11; CYTOCHROME P450 2D1; CYTOCHROME P450 3A1; CYTOCHROME P450 3A2; MESSENGER RNA; OLTIPRAZ; STREPTOZOCIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; AREA UNDER THE CURVE; ARTICLE; BLOOD FLOW VELOCITY; DIABETES MELLITUS; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG METABOLISM; LIVER BLOOD FLOW; MALE; MICROSOME; NEWBORN; NONHUMAN; PROTEIN EXPRESSION; RAT;

ADMINISTRATION, ORAL; ALLOXAN; ANIMALS; BLOOD PROTEINS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DIABETES MELLITUS, EXPERIMENTAL; HALF-LIFE; INJECTIONS, INTRAVENOUS; MALE; MICROSOMES, LIVER; PROTEIN BINDING; PYRAZINES; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; STREPTOZOCIN;

ANIMALIA;

EID: 33645405077     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lfs.2005.09.031     Document Type: Article

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