Hepatic and intestinal first-pass effects of oltipraz in rats

Biopharmaceutics and Drug Disposition

Volumn 26, Issue 4, 2005, Pages 129-134

  Bae, Soo K ^a   Kim, Jin W ^b   Kim, Young H ^b   Kim, Yoon G ^c   Kim, Sang G ^a   Lee, Myung G ^a  

^a Seoul National University   (South Korea)

^b CJ Corporation   (South Korea)

^c Dankook University   (South Korea)

Author keywords

Hepatic and intestinal first pass effects; Oltipraz; Rats

Indexed keywords

OLTIPRAZ;

ANIMAL EXPERIMENT; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG ADMINISTRATION ROUTE; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG METABOLISM; FIRST PASS EFFECT; GASTROINTESTINAL ABSORPTION; GASTROINTESTINAL TRACT FUNCTION; LIVER METABOLISM; MALE; NONHUMAN; RAT;

ADMINISTRATION, ORAL; ANIMALS; BILE; BIOLOGICAL AVAILABILITY; DUODENUM; INJECTIONS, INTRAVENOUS; INTESTINES; LIVER; MALE; METABOLIC CLEARANCE RATE; PORTAL VEIN; PYRAZINES; RATS; RATS, SPRAGUE-DAWLEY; STOMACH; TISSUE DISTRIBUTION;

EID: 17144428360     PISSN: 01422782     EISSN: None     Source Type: Journal    
DOI: 10.1002/bdd.439     Document Type: Article

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