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Volumn 78, Issue 1, 1998, Pages 17-27

Chemopreventive activity of oltipraz

Author keywords

Animal models; Chemoprevention; Clinical trials; Detoxification enzyme inducer; Oltipraz

Indexed keywords

OLTIPRAZ;

EID: 0031969218     PISSN: 01637258     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0163-7258(97)00164-2     Document Type: Review
Times cited : (79)

References (59)
  • 2
    • 0029113654 scopus 로고
    • Effects of oltipraz and related chemoprevention compounds on gene expression in rat liver
    • Anderson L., Steele V. K., Kelloff G. J., Sharma S. Effects of oltipraz and related chemoprevention compounds on gene expression in rat liver. J. Cell. Biochem. 22(Suppl.):1995;108-116.
    • (1995) J. Cell. Biochem. , vol.22 , Issue.SUPPL. , pp. 108-116
    • Anderson, L.1    Steele, V.K.2    Kelloff, G.J.3    Sharma, S.4
  • 3
    • 0011474846 scopus 로고
    • Oltipraz - Definitely withdrawn
    • Anonymous Oltipraz - Definitely withdrawn. Parasitol. Today. 1:1985;100.
    • (1985) Parasitol. Today , vol.1 , pp. 100
    • Anonymous1
  • 4
    • 0021082001 scopus 로고
    • Chemoprotective effects of two dithiolthiones and of butylhydroxyanisole against carbon tetrachloride and acetaminophen toxicity
    • Ansher S. S., Dolan P., Bueding E. Chemoprotective effects of two dithiolthiones and of butylhydroxyanisole against carbon tetrachloride and acetaminophen toxicity. Hepatology. 3:1983;932-935.
    • (1983) Hepatology , vol.3 , pp. 932-935
    • Ansher, S.S.1    Dolan, P.2    Bueding, E.3
  • 6
    • 0001140597 scopus 로고
    • Phase I study of 4-methyl-5-(2-pyrazinyl)-1,2-dithiol-3-thione (oltipraz, RP 35972) in male patients (pts) with previously resected colon polyps and first degree relatives of breast cancer pts
    • Benson A. B., Mobarhan S., Ratain M., Sheehan T., Berezin F., Giovannozzi-Bannon S., Ford C., Rademaker A. Phase I study of 4-methyl-5-(2-pyrazinyl)-1,2-dithiol-3-thione (oltipraz, RP 35972) in male patients (pts) with previously resected colon polyps and first degree relatives of breast cancer pts. Proc. Am. Soc. Clin. Oncol. 11:1992;145.
    • (1992) Proc. Am. Soc. Clin. Oncol. , vol.11 , pp. 145
    • Benson, A.B.1    Mobarhan, S.2    Ratain, M.3    Sheehan, T.4    Berezin, F.5    Giovannozzi-Bannon, S.6    Ford, C.7    Rademaker, A.8
  • 8
    • 0026553196 scopus 로고
    • Screening for chemopreventive (anticarcinogenic) compounds in rodents
    • Boone C. W., Steele V. E., Kelloff G. J. Screening for chemopreventive (anticarcinogenic) compounds in rodents. Mutat. Res. 267:1992;251-255.
    • (1992) Mutat. Res. , vol.267 , pp. 251-255
    • Boone, C.W.1    Steele, V.E.2    Kelloff, G.J.3
  • 10
    • 0028856209 scopus 로고
    • Induction of phase I and phase II drug-metabolizing enzyme mRNA, protein, and activity by BHA, ethoxyquin, and oltipraz
    • Buetler T. M., Gallagher E. P., Wang C., Stahl D. L., Hayes J. D., Eaton D. L. Induction of phase I and phase II drug-metabolizing enzyme mRNA, protein, and activity by BHA, ethoxyquin, and oltipraz. Toxicol. Appl. Pharmacol. 135:1995;45-47.
    • (1995) Toxicol. Appl. Pharmacol. , vol.135 , pp. 45-47
    • Buetler, T.M.1    Gallagher, E.P.2    Wang, C.3    Stahl, D.L.4    Hayes, J.D.5    Eaton, D.L.6
  • 11
    • 0029883290 scopus 로고    scopus 로고
    • Oltipraz-mediated changes in aflatoxin B(1) biotransformation in rat liver: Implications for human chemointervention
    • Buetler T. M., Bammler T. K., Hayes J. D., Eaton D. L. Oltipraz-mediated changes in aflatoxin B(1) biotransformation in rat liver. implications for human chemointervention Cancer Res. 56:1996;2306-2313.
    • (1996) Cancer Res. , vol.56 , pp. 2306-2313
    • Buetler, T.M.1    Bammler, T.K.2    Hayes, J.D.3    Eaton, D.L.4
  • 12
    • 0028844175 scopus 로고
    • Inactivation of human immunodeficiency virus Type 1 reverse transcriptase by oltipraz: Evidence for the formation of a stable adduct
    • Chavan S. J., Bornmann W. G., Flexner C., Prochaska H. J. Inactivation of human immunodeficiency virus Type 1 reverse transcriptase by oltipraz. evidence for the formation of a stable adduct Arch. Biochem. Biophys. 324:1995;143-152.
    • (1995) Arch. Biochem. Biophys. , vol.324 , pp. 143-152
    • Chavan, S.J.1    Bornmann, W.G.2    Flexner, C.3    Prochaska, H.J.4
  • 13
    • 0028212905 scopus 로고
    • Coordinate induction of glutathione S-transferase α, μ, and π expression in murine liver after a single administration of oltipraz
    • Clapper M. L., Everley L. C., Strobel L. A., Townsend A. J., Engstrom P. F. Coordinate induction of glutathione S-transferase α, μ, and π expression in murine liver after a single administration of oltipraz. Mol. Pharmacol. 45:1994;469-474.
    • (1994) Mol. Pharmacol. , vol.45 , pp. 469-474
    • Clapper, M.L.1    Everley, L.C.2    Strobel, L.A.3    Townsend, A.J.4    Engstrom, P.F.5
  • 14
    • 0029133232 scopus 로고
    • Chemopreventive activity of oltipraz against N-nitrosobis(2-oxopropyl)amine (BOP)-induced ductal pancreatic carcinoma development and effects on survival of Syrian golden hamsters
    • Clapper M. L., Wood M., Leahy K., Lang D., Miknyoczki S., Ruggeri B. A. Chemopreventive activity of oltipraz against N-nitrosobis(2-oxopropyl)amine (BOP)-induced ductal pancreatic carcinoma development and effects on survival of Syrian golden hamsters. Carcinogenesis. 16:1995;2159-2165.
    • (1995) Carcinogenesis , vol.16 , pp. 2159-2165
    • Clapper, M.L.1    Wood, M.2    Leahy, K.3    Lang, D.4    Miknyoczki, S.5    Ruggeri, B.A.6
  • 16
    • 0025238457 scopus 로고
    • Transcriptional control of glutathione S-transferase gene expression by the chemoprotective agent 5-(2-pyrazinyl)-4-methyl-1, 2-dithiole-3-thione (Oltipraz) in rat liver
    • Davidson N. E., Egner P. A., Kensler T. W. Transcriptional control of glutathione S-transferase gene expression by the chemoprotective agent 5-(2-pyrazinyl)-4-methyl-1, 2-dithiole-3-thione (Oltipraz) in rat liver. Cancer Res. 50:1990;2251-2255.
    • (1990) Cancer Res. , vol.50 , pp. 2251-2255
    • Davidson, N.E.1    Egner, P.A.2    Kensler, T.W.3
  • 17
    • 0023122773 scopus 로고
    • Dithiolthione-induced alterations in hepatic glutathione and related enzymes in male mice
    • Davies M. H., Blacker A. M., Schnell R. C. Dithiolthione-induced alterations in hepatic glutathione and related enzymes in male mice. Biochem. Pharmacol. 36:1987;568-570.
    • (1987) Biochem. Pharmacol. , vol.36 , pp. 568-570
    • Davies, M.H.1    Blacker, A.M.2    Schnell, R.C.3
  • 18
    • 0022739951 scopus 로고
    • 1,2-Dithiol-3-thione analogs: Effects of NAD(P)H: Quinone oxidoreductase and glutathione levels in murine hepatoma cells
    • DeLong M. J., Dolan P., Santamaria A. B., Bueding E. 1,2-Dithiol-3-thione analogs. effects of NAD(P)H: quinone oxidoreductase and glutathione levels in murine hepatoma cells Carcinogenesis. 7:1986;977-980.
    • (1986) Carcinogenesis , vol.7 , pp. 977-980
    • Delong, M.J.1    Dolan, P.2    Santamaria, A.B.3    Bueding, E.4
  • 22
    • 0029935829 scopus 로고    scopus 로고
    • Regulation of carbonyl-reducing enzymes in rat liver by chemoprotectors
    • Ellis E. M., Judah D. J., Neal G. E., O'Connor T., Hayes J. D. Regulation of carbonyl-reducing enzymes in rat liver by chemoprotectors. Cancer Res. 56:1996;2758-2766.
    • (1996) Cancer Res. , vol.56 , pp. 2758-2766
    • Ellis, E.M.1    Judah, D.J.2    Neal, G.E.3    O'Connor, T.4    Hayes, J.D.5
  • 23
    • 0019134347 scopus 로고
    • Assessment of RP 35972 (oltipraz), a new antischistosomal drug against schistosoma hematobium, schistosoma mansoni and schistosoma intercalatum
    • Gentilini M., Duflo B., Richard-Lenoble D., Brucker G., Danis M., Niel G., Meunier Y. Assessment of RP 35972 (oltipraz), a new antischistosomal drug against schistosoma hematobium, schistosoma mansoni and schistosoma intercalatum. Acta Trop. 37:1980;271-274.
    • (1980) Acta Trop. , vol.37 , pp. 271-274
    • Gentilini, M.1    Duflo, B.2    Richard-Lenoble, D.3    Brucker, G.4    Danis, M.5    Niel, G.6    Meunier, Y.7
  • 25
    • 0344743866 scopus 로고
    • Induction of detoxicating enzyme expression by metabolites of 4-methyl-5-(2-pyrazinyl)-1, 2-dithiole-3-thione (oltipraz)
    • Halbherr T., Yao K.-S., Myers C., Glusker J. P., Clayton M., O'Dwyer P. J. Induction of detoxicating enzyme expression by metabolites of 4-methyl-5-(2-pyrazinyl)-1, 2-dithiole-3-thione (oltipraz). Proc. Am. Assoc. Cancer Res. 36:1995;591.
    • (1995) Proc. Am. Assoc. Cancer Res. , vol.36 , pp. 591
    • Halbherr, T.1    Yao, K.-S.2    Myers, C.3    Glusker, J.P.4    Clayton, M.5    O'Dwyer, P.J.6
  • 28
    • 0020472320 scopus 로고
    • Dose-ranging clinical trial with oltipraz in schistosomiasis mansoni
    • Katz N., Rocha R. S., Chaves A. Dose-ranging clinical trial with oltipraz in schistosomiasis mansoni. Rev. Inst. Med. Trop. Sao Paolo. 24:1982;40-48.
    • (1982) Rev. Inst. Med. Trop. Sao Paolo , vol.24 , pp. 40-48
    • Katz, N.1    Rocha, R.S.2    Chaves, A.3
  • 29
    • 0021164385 scopus 로고
    • Assessment of oltipraz in schistosomiasis mansoni: Clinical trial
    • Katz N., Rocha R. S., Chaves A. Assessment of oltipraz in schistosomiasis mansoni. clinical trial Rev. Inst. Med. Trop. Sao Paolo. 26:1984;147-151.
    • (1984) Rev. Inst. Med. Trop. Sao Paolo , vol.26 , pp. 147-151
    • Katz, N.1    Rocha, R.S.2    Chaves, A.3
  • 32
    • 0023204238 scopus 로고
    • Mechanism of protection against aflatoxin tumorigenicity in rats fed 5-(2-pyrazinyl)-4-methyl-1, 2-dithiol-3-thione (oltipraz) and related 1,2-dithiol-3-thiones and 1,2-dithiol-3-ones
    • Kensler T. W., Egner P. A., Dolan P. M., Groopman J. D., Roebuck B. D. Mechanism of protection against aflatoxin tumorigenicity in rats fed 5-(2-pyrazinyl)-4-methyl-1, 2-dithiol-3-thione (oltipraz) and related 1,2-dithiol-3-thiones and 1,2-dithiol-3-ones. Cancer Res. 47:1987;4271-4277.
    • (1987) Cancer Res. , vol.47 , pp. 4271-4277
    • Kensler, T.W.1    Egner, P.A.2    Dolan, P.M.3    Groopman, J.D.4    Roebuck, B.D.5
  • 34
    • 0029155418 scopus 로고
    • Regional chemoprevention of carcinogen-induced tumors in rat colon
    • Liu T., Mokuolu A. O., Rao C. V., Reddy B. S., Holt P. R. Regional chemoprevention of carcinogen-induced tumors in rat colon. Gastroenterology. 109:1995;1167-1172.
    • (1995) Gastroenterology , vol.109 , pp. 1167-1172
    • Liu, T.1    Mokuolu, A.O.2    Rao, C.V.3    Reddy, B.S.4    Holt, P.R.5
  • 37
    • 0025741216 scopus 로고
    • Characterization of effective chemopreventive agents in mammary gland in vitro using an initiation-promotion protocol
    • Mehta R. G., Moon R. C. Characterization of effective chemopreventive agents in mammary gland in vitro using an initiation-promotion protocol. Anticancer Res. 11:1991;593-596.
    • (1991) Anticancer Res. , vol.11 , pp. 593-596
    • Mehta, R.G.1    Moon, R.C.2
  • 38
    • 0027212969 scopus 로고
    • Quantitation of tissue- And sex-specific induction of rat GSH transferase subunits by dietary 1,2-dithiole-3-thiones
    • Meyer D. J., Harris J. M., Gilmore K. S., Coles B., Kensler T. W., Ketterer B. Quantitation of tissue- and sex-specific induction of rat GSH transferase subunits by dietary 1,2-dithiole-3-thiones. Carcinogenesis. 14:1993;567-572.
    • (1993) Carcinogenesis , vol.14 , pp. 567-572
    • Meyer, D.J.1    Harris, J.M.2    Gilmore, K.S.3    Coles, B.4    Kensler, T.W.5    Ketterer, B.6
  • 39
    • 0028179948 scopus 로고
    • Chemoprevention of OH-BBN-induced bladder cancer in mice by oltipraz, alone and in combination with 4-HPR and DFMO
    • a
    • Moon R. C., Kelloff G. J., Detrisac C. J., Steele V. E., Thomas C. F., Sigman C. C. Chemoprevention of OH-BBN-induced bladder cancer in mice by oltipraz, alone and in combination with 4-HPR and DFMO. Anticancer Res. 14:1994;5-12. a.
    • (1994) Anticancer Res. , vol.14 , pp. 5-12
    • Moon, R.C.1    Kelloff, G.J.2    Detrisac, C.J.3    Steele, V.E.4    Thomas, C.F.5    Sigman, C.C.6
  • 40
    • 0028295163 scopus 로고
    • Chemoprevention of respiratory tract neoplasia in the hamster by oltipraz, alone and in combination
    • b
    • Moon R. C., Rao K. V. N., Detrisac C. J., Kelloff G. J., Steele V. E., Doody L. A. Chemoprevention of respiratory tract neoplasia in the hamster by oltipraz, alone and in combination. Int. J. Oncol. 4:1994;661-667. b.
    • (1994) Int. J. Oncol. , vol.4 , pp. 661-667
    • Moon, R.C.1    Rao, K.V.N.2    Detrisac, C.J.3    Kelloff, G.J.4    Steele, V.E.5    Doody, L.A.6
  • 42
    • 0027497708 scopus 로고
    • Preferential increase of glutathione S-transferase class α transcripts in cultured human hepatocytes by phenobarbital, 3-methylcholanthrene, and dithiolethiones
    • Morel F., Fardel O., Meyer D. J., Langouet S., Gilmore K. S., Meunier B., Tu C.-P. D., Kensler T. W., Ketterer B., Guillouzo A. Preferential increase of glutathione S-transferase class α transcripts in cultured human hepatocytes by phenobarbital, 3-methylcholanthrene, and dithiolethiones. Cancer Res. 53:1993;231-234.
    • (1993) Cancer Res. , vol.53 , pp. 231-234
    • Morel, F.1    Fardel, O.2    Meyer, D.J.3    Langouet, S.4    Gilmore, K.S.5    Meunier, B.6    Tu C.-P., D.7    Kensler, T.W.8    Ketterer, B.9    Guillouzo, A.10
  • 43
    • 0029032689 scopus 로고
    • Failure of dietary oltipraz to inhibit benzo[a]pyrene-induced lung tumorigenesis in strain A mice
    • Morse M. A., Zu H., Kresty L. A., Stoner G. D. Failure of dietary oltipraz to inhibit benzo[a]pyrene-induced lung tumorigenesis in strain A mice. Cancer Lett. 91:1995;133-138.
    • (1995) Cancer Lett. , vol.91 , pp. 133-138
    • Morse, M.A.1    Zu, H.2    Kresty, L.A.3    Stoner, G.D.4
  • 46
    • 0026604162 scopus 로고
    • Effects of sulindac and oltipraz on the tumorigenicity of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in A/J mouse lung
    • Pepin P., Bouchard L., Nicole P., Castonguay A. Effects of sulindac and oltipraz on the tumorigenicity of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in A/J mouse lung. Carcinogenesis. 13:1992;341-348.
    • (1992) Carcinogenesis , vol.13 , pp. 341-348
    • Pepin, P.1    Bouchard, L.2    Nicole, P.3    Castonguay, A.4
  • 47
    • 0029048396 scopus 로고
    • Intermittent dosing with oltipraz-relationship between chemoprevention of aflatoxin-induced tumorigenesis and induction of glutathione S-transferases
    • Primiano T., Egner P. A., Sutter T. R., Kelloff G. J., Roebuck B. D., Kensler T. W. Intermittent dosing with oltipraz-relationship between chemoprevention of aflatoxin-induced tumorigenesis and induction of glutathione S-transferases. Cancer Res. 55:1995;4319-4324.
    • (1995) Cancer Res. , vol.55 , pp. 4319-4324
    • Primiano, T.1    Egner, P.A.2    Sutter, T.R.3    Kelloff, G.J.4    Roebuck, B.D.5    Kensler, T.W.6
  • 48
    • 0023777834 scopus 로고
    • Regulatory mechanisms of monofunctional and bifunctional anticarcinogenic enzyme inducers in murine liver
    • Prochaska H. J., Talalay P. Regulatory mechanisms of monofunctional and bifunctional anticarcinogenic enzyme inducers in murine liver. Cancer Res. 48:1988;4776-4782.
    • (1988) Cancer Res. , vol.48 , pp. 4776-4782
    • Prochaska, H.J.1    Talalay, P.2
  • 49
    • 0029153008 scopus 로고
    • Inhibition of human immunodeficiency virus Type I replication by 7-methyl-6,8-bis(methylthio)pyrrolo[1,2-a]pyrazine, an in vivo metabolite of oltipraz
    • Prochaska H. J., Bornmann W. G., Baron P., Polsky B. Inhibition of human immunodeficiency virus Type I replication by 7-methyl-6,8-bis(methylthio)pyrrolo[1,2-a]pyrazine, an in vivo metabolite of oltipraz. Mol. Pharmacol. 48:1995;15-20.
    • (1995) Mol. Pharmacol. , vol.48 , pp. 15-20
    • Prochaska, H.J.1    Bornmann, W.G.2    Baron, P.3    Polsky, B.4
  • 50
    • 0030001461 scopus 로고    scopus 로고
    • Inhibition of human immunodeficiency virus type 1 long terminal repeat-driven transcription by an in vivo metabolite of oltipraz: Implications for antiretroviral therapy
    • Prochaska H. J., Pernandes C. L., Pantoja R. M., Chavan S. J. Inhibition of human immunodeficiency virus type 1 long terminal repeat-driven transcription by an in vivo metabolite of oltipraz. implications for antiretroviral therapy Biochem. Biophys. Res. Commun. 221:1996;548-553.
    • (1996) Biochem. Biophys. Res. Commun. , vol.221 , pp. 548-553
    • Prochaska, H.J.1    Pernandes, C.L.2    Pantoja, R.M.3    Chavan, S.J.4
  • 51
    • 0025811288 scopus 로고
    • Effect of oltipraz [5-(2-pyrazinyl)-4-methyl-1,2-dithiol-3-thione] on azoxymethane-induced biochemical changes related to early colon carcinogenesis in male F344 rats
    • a
    • Rao C. V., Nayini J., Reddy B. S. Effect of oltipraz [5-(2-pyrazinyl)-4-methyl-1,2-dithiol-3-thione] on azoxymethane-induced biochemical changes related to early colon carcinogenesis in male F344 rats. Proc. Soc. Exp. Biol. Med. 197:1991;77-84. a.
    • (1991) Proc. Soc. Exp. Biol. Med. , vol.197 , pp. 77-84
    • Rao, C.V.1    Nayini, J.2    Reddy, B.S.3
  • 52
    • 0025783095 scopus 로고
    • Inhibition by dietary oltipraz of experimental intestinal carcinogenesis induced by azoxymethane in male F344 rats
    • b
    • Rao C. V., Tokomo K., Kelloff G., Reddy B. S. Inhibition by dietary oltipraz of experimental intestinal carcinogenesis induced by azoxymethane in male F344 rats. Carcinogenesis. 12:1991;1051-1055. b.
    • (1991) Carcinogenesis , vol.12 , pp. 1051-1055
    • Rao, C.V.1    Tokomo, K.2    Kelloff, G.3    Reddy, B.S.4
  • 53
    • 0027156962 scopus 로고
    • Chemopreventive effect of oltipraz during different stages of experimental colon carcinogenesis induced by azoxymethane in male F344 rats
    • Rao C. V., Rivenson A., Katiwalla M., Kelloff G. J., Reddy B. S. Chemopreventive effect of oltipraz during different stages of experimental colon carcinogenesis induced by azoxymethane in male F344 rats. Cancer Res. 53:1993;2502-2506.
    • (1993) Cancer Res. , vol.53 , pp. 2502-2506
    • Rao, C.V.1    Rivenson, A.2    Katiwalla, M.3    Kelloff, G.J.4    Reddy, B.S.5
  • 54
    • 0029682493 scopus 로고    scopus 로고
    • Inhibition of 2-amino-1-methyl-6-phenylimidazo[4,5-B]pyridine-induced lymphoma formation by oltipraz
    • Rao C. V., Rivenson A., Zang E., Steele V., Kelloff G., Reddy B. S. Inhibition of 2-amino-1-methyl-6-phenylimidazo[4,5-B]pyridine-induced lymphoma formation by oltipraz. Cancer Res. 56:1996;3395-3398.
    • (1996) Cancer Res. , vol.56 , pp. 3395-3398
    • Rao, C.V.1    Rivenson, A.2    Zang, E.3    Steele, V.4    Kelloff, G.5    Reddy, B.S.6
  • 55
    • 0006863388 scopus 로고    scopus 로고
    • Modulation of dibenz[a, l]pyrene-DNA adduction by chemopreventive agents in the human breast epithelial cell line
    • Smith W. A., Freeman J. W., Gupta R. C. Modulation of dibenz[a, l]pyrene-DNA adduction by chemopreventive agents in the human breast epithelial cell line. Proc. Am. Assoc. Cancer Res. 38:1997;362.
    • (1997) Proc. Am. Assoc. Cancer Res. , vol.38 , pp. 362
    • Smith, W.A.1    Freeman, J.W.2    Gupta, R.C.3
  • 58
    • 0022763396 scopus 로고
    • Inhibitory effects of 5-(2-pyrazinyl)-4-methyl-1,2-dithiol-3-thione (Oltipraz) on carcinogenesis induced by benzo[a]pyrene, diethylnitrosamine and uracil mustard
    • Wattenberg L. W., Bueding E. Inhibitory effects of 5-(2-pyrazinyl)-4-methyl-1,2-dithiol-3-thione (Oltipraz) on carcinogenesis induced by benzo[a]pyrene, diethylnitrosamine and uracil mustard. Carcinogenesis. 7:1986;1379-1381.
    • (1986) Carcinogenesis , vol.7 , pp. 1379-1381
    • Wattenberg, L.W.1    Bueding, E.2
  • 59
    • 0028978712 scopus 로고
    • Involvement of NF-κB in the induction of NAD(P)H:quinone oxidoreductase (DT-diaphorase) by hypoxia, oltipraz and mitomycin C
    • Yao K.-S., O'Dwyer P. J. Involvement of NF-κB in the induction of NAD(P)H:quinone oxidoreductase (DT-diaphorase) by hypoxia, oltipraz and mitomycin C. Biochem. Pharmacol. 49:1995;275-282.
    • (1995) Biochem. Pharmacol. , vol.49 , pp. 275-282
    • Yao, K.-S.1    O'Dwyer, P.J.2


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