Mixed-micellar proliposomal systems for enhanced oral delivery of progesterone

Drug Delivery: Journal of Delivery and Targeting of Therapeutic Agents

Volumn 13, Issue 3, 2006, Pages 227-232

  Potluri, Praveen ^a   Betageri, Guru V ^a  

^a WESTERN UNIVERSITY OF HEALTH SCIENCES   (United States)

Author keywords

Dissolution; Mixed Micelle; Oral Bioavailability Progesterone; Proliposomes

Indexed keywords

DIMYRISTOYLPHOSPHATIDYLCHOLINE; LIPID; LIPOSOME; MICROCRYSTALLINE CELLULOSE; PHOSPHATIDYLCHOLINE; POLYSORBATE 80; PROGESTERONE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL STRAIN CACO 2; COMPARATIVE STUDY; CONTROLLED STUDY; DRUG ADMINISTRATION ROUTE; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG SOLUBILITY; DRUG TRANSPORT; HUMAN; HUMAN CELL; INTESTINE; MEMBRANE TRANSPORT; MICELLIZATION; NONHUMAN; PRIORITY JOURNAL; RAT;

ADMINISTRATION, ORAL; ANIMALS; BIOLOGICAL AVAILABILITY; BIOLOGICAL TRANSPORT; CACO-2 CELLS; CALORIMETRY, DIFFERENTIAL SCANNING; CELLULOSE; DIMYRISTOYLPHOSPHATIDYLCHOLINE; DRUG CARRIERS; EXCIPIENTS; HUMANS; INTESTINES; LIPOSOMES; MICELLES; PARTICLE SIZE; PHOSPHATIDYLCHOLINES; POLYSORBATES; PROGESTERONE; RATS; RATS, SPRAGUE-DAWLEY;

EID: 33645306276     PISSN: 10717544     EISSN: 15210464     Source Type: Journal    
DOI: 10.1080/10717540500395007     Document Type: Article

References (23)

1. Ali, S., Minchey, S., Janoff, A., and Mayhew, E. 2000. A differential scanning calorimetry study of phosphocholines mixed with paclitaxel and its bromoacylates taxanes. Biophys. J. 78:246-256.
2. Allen Jr., L. V., Levinson, R. S., Robinson, C., and Lau, A. 1981. Effect of surfactant on tetracycline absorption across everted rat intestine. J. Pharm. Sci. 70:269-271.
3. Amidon, G. L., Lennernas, H., Shah, V. P., and Crison, J. R. 1995. A theoretical basis for a biopharmaceutic drug classification: the correlation of in vitro drug product dissolution and in vivo bioavailability. Pharm. Res. 12:413-420.
4. Betageri, G. V. 2004. Enteric-coated proliposomal formulations for poorly water soluble drugs. U.S. Patent. No. 6,759,058.
5. Betageri, G. V. 2005. Proliposomal drug delivery system. U.S. Patent. No. 6,849,269.
6. Brocks, D. R., and Betageri, G. V. 2002. Enhanced oral absorption of halofantrine enantiomers after encapsulation in a proliposomal formulation. J. Pharm. Pharmacol. 54:1049-1053.
7. Charman, W. N. 2000. Lipids, lipophilic drugs, and oral drag delivery - some emerging concepts. J. Pharm. Sci. 89:967-978.
8. Chen, H., Torchilin, V., and Langer, R. 1996. Lectin-bearing polymerized liposomes as potential oral vaccine carriers. Pharm. Res. 13:1378-1383.
9. Chung, S. 1999. Future drug delivery research in South Korea. J. Control. Rel. 62:73-79.
10. Jung, B. H., Chung, B. C., and Chung, S. J., et al. 2000. Prolonged delivery of nicotine in rats via nasal administration of proliposomes. J. Control. Rel. 66:73-79.
11. Karpf, D. M., Holm, R., Kristensen, H. G., and Mullertz, A. 2004. Influence of the type of surfactant and the degree of dispersion on the lymphatic transport of halofantrine in conscious rats. Pharm. Res. 21:1413-1418.
12. Kumar, R., Gupta, R. B., and Betageri, G. V. 2001. Formulation, characterization, and in vitro release of glyburide from proliposomal beads. Drug. Del. 8:25-27.
13. Nerurkar, M. M., Burton, P. S., and Borchardt, R. T. 1996. The use of surfactants to enhance the permeability of peptides through caco-2 cells by inhibition of an apically polarized efflux system. Pharm. Res. 13:528-534.
14. Ottosson, U. B., Carlstorm, K., Damber, J. E., and Von Shultz, B. 1984. Proliposomal formulation of progesterone. Br. J. Obstet. Gynaecol. 91:1111-1119.
15. Pavelic, Z., Skalko-Basnet, N., and Schubert, R. 2001. Liposomal gels for vaginal delivery. Int. J. Pharm. 219:139-149.
16. Payne, N. I., Timmins, P., and Ambrose, C. V., et al. 1986. Proliposomes: a novel solution to an old problem. J. Pharm. Sci. 75:325-329.
17. Porter, C. J. H., and Charman, W. N. 2001. Intestinal lymphatic drug transport: an update. Adv. Drug Deliv. Rev. 50:21-14.
18. Ravis, W. R., and Feldman, S. 1978. Effect of enzyme-inducing and enzyme-inhibiting agents on drug absorption 1: 3-O-methyl glucose transport in rats. J. Pharm. Sci 67:245-248.
19. Rogers, J. A., and Anderson, J. E. 1998. The potential of liposomes in oral drug delivery. Crit. Rev. Ther. Drug Carrier. Syst. 15:421-480.
20. Sarbolouki, M. N., Parsaee, S., and Kosary, P. 2000. Mixed micelle proliposomes for preparation of liposomes containing amphotericin B, in-vitro and ex-vivo studies. PDA. J. Sci. Technol. 54:240-246.
21. Seeballuck, F., Lawless, E., Ashford, M. B., and O'Driscoll, C. M. 2004. Stimulation of triglyceride-rich lipoprotein secretion by polysorbate 80: in vitro and in vivo correlation using caco-2 cells and a cannulated rat intestinal lymphatic model. Pharm. Res. 21:2320-2326.
22. Supersaxo, A., Hein, W. R., and Steffen, H. 1991. Mixed micelles as a proliposomal, lymphotropic drug carrier. Pharm. Res. 8:1286-1291.
23. Thomas, T., Rhodin, J. L., Clark, L., and Garces, A. 2003. Progestins initiate adverse events of menopausal estrogen therapy. Climacteric. 6:265-267.