메뉴 건너뛰기




Volumn 26, Issue 2, 2006, Pages 162-168

The cytotoxic effect of anthrax lethal toxin on human lung cells in vitro and the protective action of bovine antibodies to PA and LF

Author keywords

Anthrax; Bovine antibodies; Cytotoxicity; Exotoxins; Human lung epithelial cells; Human lung microvascular endothelial cells; Lethal factor; Lungs; Protective antigen

Indexed keywords

ANTHRAX LETHAL FACTOR; ANTHRAX TOXIN; ANTIBODY; BOVINE ANTIBODY; EXOTOXIN; RECEPTOR; TOXIN PROTECTIVE ANTIGEN; UNCLASSIFIED DRUG;

EID: 33645276822     PISSN: 0260437X     EISSN: 10991263     Source Type: Journal    
DOI: 10.1002/jat.1119     Document Type: Article
Times cited : (9)

References (45)
  • 5
    • 5344228698 scopus 로고    scopus 로고
    • The use of a model of in vivo macrophage depletion to study the role of macrophages during infection with Bacillus arthracis spores
    • Cote CK, Rea KM, Norris SL, van Rooijen N, Welkos SL. 2004. The use of a model of in vivo macrophage depletion to study the role of macrophages during infection with Bacillus arthracis spores. Microb. Pathog. 37: 169-175.
    • (2004) Microb. Pathog. , vol.37 , pp. 169-175
    • Cote, C.K.1    Rea, K.M.2    Norris, S.L.3    Van Rooijen, N.4    Welkos, S.L.5
  • 7
    • 0034524336 scopus 로고    scopus 로고
    • Early Bacillus anthracis-macrophage interactions: Intracellular survival and escape
    • Dixon TC, Fadl AA, Koehler TM, Swanson JA, Hanna PC. 2000. Early Bacillus anthracis-macrophage interactions: intracellular survival and escape. Cell. Microbiol. 2: 453-463.
    • (2000) Cell. Microbiol. , vol.2 , pp. 453-463
    • Dixon, T.C.1    Fadl, A.A.2    Koehler, T.M.3    Swanson, J.A.4    Hanna, P.C.5
  • 8
    • 0002997739 scopus 로고    scopus 로고
    • Permeability of the blood-gas barrier
    • Crystal RG, West JB, Weibel ER, Barnes PJ (eds), 2nd edn. Lippincott-Raven: New York
    • Effros RM. 1997. Permeability of the blood-gas barrier. In The Lung: Scientific Foundations, Crystal RG, West JB, Weibel ER, Barnes PJ (eds), 2nd edn. Lippincott-Raven: New York; 1567-1580.
    • (1997) The Lung: Scientific Foundations , pp. 1567-1580
    • Effros, R.M.1
  • 9
    • 0035142005 scopus 로고    scopus 로고
    • Macrophage-derived cell lines do not express proinflammatory cytokines after exposure to Bacillus anthracis lethal toxin
    • Erwin JL, DaSilva LM, Bavari S, Little SF, Friedlander AM, Chanh TC. 2001. Macrophage-derived cell lines do not express proinflammatory cytokines after exposure to Bacillus anthracis lethal toxin. Infect. Immun. 69: 1175-1177.
    • (2001) Infect. Immun. , vol.69 , pp. 1175-1177
    • Erwin, J.L.1    DaSilva, L.M.2    Bavari, S.3    Little, S.F.4    Friedlander, A.M.5    Chanh, T.C.6
  • 10
  • 11
    • 0022891493 scopus 로고
    • Macrophages are sensitive to anthrax lethal toxin through an acid-dependent process
    • Friedlander AM. 1986. Macrophages are sensitive to anthrax lethal toxin through an acid-dependent process. J. Biol. Chem. 261: 7123-7126.
    • (1986) J. Biol. Chem. , vol.261 , pp. 7123-7126
    • Friedlander, A.M.1
  • 12
  • 14
    • 0036667336 scopus 로고    scopus 로고
    • Inhalational anthrax: Gross autopsy findings
    • Gill JR, Melinek J. 2002. Inhalational anthrax: Gross autopsy findings. Arch. Pathol. Lab. Med. 126: 993-994.
    • (2002) Arch. Pathol. Lab. Med. , vol.126 , pp. 993-994
    • Gill, J.R.1    Melinek, J.2
  • 16
    • 0035170561 scopus 로고    scopus 로고
    • Fate of germinated Bacillus anthracis spores in primary murine macrophages
    • Guidi-Rontani C, Levy M, Ohayon H, Mock M. 2001. Fate of germinated Bacillus anthracis spores in primary murine macrophages. Mol. Microbiol. 42: 931-938.
    • (2001) Mol. Microbiol. , vol.42 , pp. 931-938
    • Guidi-Rontani, C.1    Levy, M.2    Ohayon, H.3    Mock, M.4
  • 19
    • 0027097608 scopus 로고
    • Biochemical and physiological changes induced by anthrax lethal toxin in J774 macrophage-like cells
    • Hanna PC, Kochi S, Collier RJ. 1992. Biochemical and physiological changes induced by anthrax lethal toxin in J774 macrophage-like cells. Moll. Biol. Cell. 3: 1269-1277.
    • (1992) Moll. Biol. Cell. , vol.3 , pp. 1269-1277
    • Hanna, P.C.1    Kochi, S.2    Collier, R.J.3
  • 20
    • 0000823103 scopus 로고
    • The chemical basis of the virulence of Bacillus anthracis. III: The role of terminal bacteraemia in death of guinea pigs from anthrax
    • Keppie J, Smith H, Harris-Smith PW. 1955. The chemical basis of the virulence of Bacillus anthracis. III: The role of terminal bacteraemia in death of guinea pigs from anthrax. Br. J. Exp. Pathol. 36: 315-322.
    • (1955) Br. J. Exp. Pathol. , vol.36 , pp. 315-322
    • Keppie, J.1    Smith, H.2    Harris-Smith, P.W.3
  • 21
    • 0346251030 scopus 로고    scopus 로고
    • Anthrax lethal toxin induces human endothelial cell apoptosis
    • Kirby JE. 2004. Anthrax lethal toxin induces human endothelial cell apoptosis. Infect. Immun. 72: 430-439.
    • (2004) Infect. Immun. , vol.72 , pp. 430-439
    • Kirby, J.E.1
  • 22
    • 0036151173 scopus 로고    scopus 로고
    • Efficiency of protection of guinea pigs against infection with Bacillus anthracis spores by passive immunization
    • Kobiler D, Gozes Y, Rosenberg H, Marcus D, Reuveny S, Altboum Z. 2002. Efficiency of protection of guinea pigs against infection with Bacillus anthracis spores by passive immunization. Infect. Immun. 70: 544-550.
    • (2002) Infect. Immun. , vol.70 , pp. 544-550
    • Kobiler, D.1    Gozes, Y.2    Rosenberg, H.3    Marcus, D.4    Reuveny, S.5    Altboum, Z.6
  • 24
    • 0030785493 scopus 로고    scopus 로고
    • Passive protection by polyclonal antibodies against Bacillus anthracis infection in guinea pigs
    • Little SF, Ivins BE, Fellows PF, Friedlander AM. 1997. Passive protection by polyclonal antibodies against Bacillus anthracis infection in guinea pigs. Infect. Immun. 65: 5171-5175.
    • (1997) Infect. Immun. , vol.65 , pp. 5171-5175
    • Little, S.F.1    Ivins, B.E.2    Fellows, P.F.3    Friedlander, A.M.4
  • 25
    • 0025290784 scopus 로고
    • Production and characterization of monoclonal antibodies against the lethal factor component of Bacillus anthracis lethal toxin
    • Little SF, Leppla SH, Friedlander AM. 1990. Production and characterization of monoclonal antibodies against the lethal factor component of Bacillus anthracis lethal toxin. Infect. Immun. 58: 1606-1613.
    • (1990) Infect. Immun. , vol.58 , pp. 1606-1613
    • Little, S.F.1    Leppla, S.H.2    Friedlander, A.M.3
  • 27
    • 85047692288 scopus 로고    scopus 로고
    • Bacillus anthracis lethal toxin induces TNF-α-independent hypoxia-mediated toxicity in mice
    • Moayeri M, Haines D, Young HA, Leppla SH. 2003. Bacillus anthracis lethal toxin induces TNF-α-independent hypoxia-mediated toxicity in mice. J. Clin. Invest. 112: 670-682.
    • (2003) J. Clin. Invest. , vol.112 , pp. 670-682
    • Moayeri, M.1    Haines, D.2    Young, H.A.3    Leppla, S.H.4
  • 28
    • 3342965783 scopus 로고    scopus 로고
    • Mouse susceptibility to anthrax lethal toxin is influenced by genetic factors in addition to those controlling macrophage sensitivity
    • Moayeri M, Martinez NW, Wiggins J, Young HA, Leppla SH. 2004. Mouse susceptibility to anthrax lethal toxin is influenced by genetic factors in addition to those controlling macrophage sensitivity. Infect. Immun. 72: 4439-447.
    • (2004) Infect. Immun. , vol.72 , pp. 4439-4447
    • Moayeri, M.1    Martinez, N.W.2    Wiggins, J.3    Young, H.A.4    Leppla, S.H.5
  • 29
    • 19944432972 scopus 로고    scopus 로고
    • A high-affinity monoclonal antibody to anthrax protective antigen protects rabbits before and after Bacillus anthracis spore challenge
    • Mohamed N, Clagett M, Li J, Jones S, Pincus S, D'Alia G, Nardone L. Babin M, Spitalny G, Casey L. 2005. A high-affinity monoclonal antibody to anthrax protective antigen protects rabbits before and after Bacillus anthracis spore challenge. Infect. Immun. 73: 795-802.
    • (2005) Infect. Immun. , vol.73 , pp. 795-802
    • Mohamed, N.1    Clagett, M.2    Li, J.3    Jones, S.4    Pincus, S.5    D'Alia, G.6    Nardone, L.7    Babin, M.8    Spitalny, G.9    Casey, L.10
  • 30
    • 27144496222 scopus 로고    scopus 로고
    • Evaluation of the neutralizing activity of antibodies against ricin in a cytotoxicity assay utilizing human lung epithelial cells
    • DSTO-TR-1418
    • Paddle BM, Poretski M. 2003. Evaluation of the neutralizing activity of antibodies against ricin in a cytotoxicity assay utilizing human lung epithelial cells. Defence Science and Technology Organization. Australia, Technical Report DSTO-TR-1418.
    • (2003) Defence Science and Technology Organization. Australia, Technical Report
    • Paddle, B.M.1    Poretski, M.2
  • 31
    • 3242678060 scopus 로고    scopus 로고
    • Knock-on effect of anthrax lethal toxin on macrophages potentiates cytotoxicity to endothelial cells
    • Pandey J, Warburton D. 2004. Knock-on effect of anthrax lethal toxin on macrophages potentiates cytotoxicity to endothelial cells. Microbes Infect. 6: 835-843.
    • (2004) Microbes Infect. , vol.6 , pp. 835-843
    • Pandey, J.1    Warburton, D.2
  • 32
    • 0037144590 scopus 로고    scopus 로고
    • Macrophage apoptosis by anthrax lethal factor through p38 MAP kinase inhibition
    • Park JM, Greten FR, Li ZW, Karin M. 2002. Macrophage apoptosis by anthrax lethal factor through p38 MAP kinase inhibition. Science 297: 2048-2051.
    • (2002) Science , vol.297 , pp. 2048-2051
    • Park, J.M.1    Greten, F.R.2    Li, Z.W.3    Karin, M.4
  • 33
    • 0032755353 scopus 로고    scopus 로고
    • Anthrax lethal factor cleaves MKK3 in macrophages and inhibits the LPS/IFN gamma-induced release of NO and TNF alpha
    • Pellizzari R, Guidi-Rontani C, Vitale G, Mock M, Montecucco C. 1999. Anthrax lethal factor cleaves MKK3 in macrophages and inhibits the LPS/IFN gamma-induced release of NO and TNF alpha. FEBS Lett. 462: 199-204.
    • (1999) FEBS Lett. , vol.462 , pp. 199-204
    • Pellizzari, R.1    Guidi-Rontani, C.2    Vitale, G.3    Mock, M.4    Montecucco, C.5
  • 34
    • 4243206315 scopus 로고
    • Morphology of the respiratory tract
    • McClellan RO, Henderson RF (eds), 2nd edn. Taylor and Francis: Washington
    • Phalen RF, Yeh HC, Prasad SB. 1995. Morphology of the respiratory tract. In Concepts in Inhalation Toxicology, McClellan RO, Henderson RF (eds), 2nd edn. Taylor and Francis: Washington; 129-149.
    • (1995) Concepts in Inhalation Toxicology , pp. 129-149
    • Phalen, R.F.1    Yeh, H.C.2    Prasad, S.B.3
  • 39
    • 0001663333 scopus 로고
    • Pathogenesis of anthrax following administration of spores by the respiratory route
    • Ross JM. 1957. Pathogenesis of anthrax following administration of spores by the respiratory route. J. Pathol. Bacteriol. 73: 485-494.
    • (1957) J. Pathol. Bacteriol. , vol.73 , pp. 485-494
    • Ross, J.M.1
  • 40
    • 1842450833 scopus 로고    scopus 로고
    • Time-lapse confocal imaging of developmemt of Bacillus anthracis in macrophages
    • Ruthel G, Ribot WJ, Bavari S. Hoover TA. 2004. Time-lapse confocal imaging of developmemt of Bacillus anthracis in macrophages. J. Infect. Dis. 189: 1313-1316.
    • (2004) J. Infect. Dis. , vol.189 , pp. 1313-1316
    • Ruthel, G.1    Ribot, W.J.2    Bavari, S.3    Hoover, T.A.4
  • 42
  • 43
    • 0036194289 scopus 로고    scopus 로고
    • Discovery of the anthrax toxin: The beginning of studies of virulence determinants regulated in vivo
    • Smith H. 2002. Discovery of the anthrax toxin: the beginning of studies of virulence determinants regulated in vivo. Int. J. Med. Microbiol. 291: 411-417.
    • (2002) Int. J. Med. Microbiol. , vol.291 , pp. 411-417
    • Smith, H.1
  • 44
    • 19544371576 scopus 로고    scopus 로고
    • Anthrax lethal toxin induces endothelial barrier dysfunction
    • Warfel JM, Steele AD, D'Agnillo F. 2005. Anthrax lethal toxin induces endothelial barrier dysfunction. Am. J. Pathol. 166: 1871-1881.
    • (2005) Am. J. Pathol. , vol.166 , pp. 1871-1881
    • Warfel, J.M.1    Steele, A.D.2    D'Agnillo, F.3
  • 45
    • 0000550971 scopus 로고    scopus 로고
    • Design and morphometry of the pulmonary gas exchanger
    • Crystal RG, West JB, Weibel ER, Barnes PJ (eds), 2nd edn. Lippincott-Raven: New York
    • Weibel ER. 1997. Design and morphometry of the pulmonary gas exchanger. In The Lung: Scientific Foundations, Crystal RG, West JB, Weibel ER, Barnes PJ (eds), 2nd edn. Lippincott-Raven: New York; 1147-1157.
    • (1997) The Lung: Scientific Foundations , pp. 1147-1157
    • Weibel, E.R.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.