Discrimination of cognate and noncognate substrates at the active site of class I Lysyl-tRNA synthetase

Biochemistry

Volumn 45, Issue 11, 2006, Pages 3646-3652

  Wang, Shiming ^a   Prætorius Ibba, Mette ^a   Ataide, Sandra F ^a   Roy, Hervé ^a   Ibba, Michael ^a  

^a OHIO STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACYLATION; AMINO ACIDS; CATALYSIS; HYDROGEN BONDS; HYDROPHOBICITY; RNA;

AMINOACYLATION; HOMOLOGY; PYROCOCCUS HORIKOSHII; STRUCTURAL CLASSES;

ENZYMES;

AMINO ACID TRANSFER RNA LIGASE; LYSINE; LYSINE TRANSFER RNA; LYSINE TRANSFER RNA LIGASE; LYSINE TRANSFER RNA LIGASE 1; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; AMINOACYLATION; ARTICLE; BORRELIA BURGDORFERI; COMPLEX FORMATION; ELECTRICITY; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME SPECIFICITY; ENZYME STRUCTURE; ENZYME SUBSTRATE; HYDROGEN BOND; HYDROPHOBICITY; NONHUMAN; PRIORITY JOURNAL; PYROCOCCUS HORIKOSHII; STEADY STATE; STRUCTURE ANALYSIS; WILD TYPE;

AMINO ACID SEQUENCE; AMINOACYLATION; BACTERIAL PROTEINS; BINDING SITES; BORRELIA BURGDORFERI; CATALYSIS; HYDROGEN BONDING; HYDROPHOBICITY; LYSINE; LYSINE-TRNA LIGASE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; POINT MUTATION; SEQUENCE ALIGNMENT; SUBSTRATE SPECIFICITY;

BORRELIA BURGDORFERI; PYROCOCCUS HORIKOSHII;

EID: 33645229971     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi0523005     Document Type: Article

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