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Volumn 188, Issue 7, 2006, Pages 2674-2680

Molecular and physiological effects of mycobacterial oxyR inactivation

Author keywords

[No Author keywords available]

Indexed keywords

ALKYLHYDROPEROXIDE REDUCTASE; BACTERIAL DNA; CATALASE; CUMENE HYDROPEROXIDE; HYDROGEN PEROXIDE; ISONIAZID; OXIDOREDUCTASE; TUBERCULOSTATIC AGENT; UNCLASSIFIED DRUG;

EID: 33645221138     PISSN: 00219193     EISSN: None     Source Type: Journal    
DOI: 10.1128/JB.188.7.2674-2680.2006     Document Type: Article
Times cited : (27)

References (44)
  • 1
    • 0031656741 scopus 로고    scopus 로고
    • The identification of Mycobacterium marinum genes differentially expressed in macrophage phagosomes using promoter fusions to green fluorescent protein
    • Barker, L. P., D. M. Brooks, and P. L. Small. 1998. The identification of Mycobacterium marinum genes differentially expressed in macrophage phagosomes using promoter fusions to green fluorescent protein. Mol. Microbiol. 29:1167-1177.
    • (1998) Mol. Microbiol. , vol.29 , pp. 1167-1177
    • Barker, L.P.1    Brooks, D.M.2    Small, P.L.3
  • 2
    • 0035179747 scopus 로고    scopus 로고
    • Dynamic nature of host-pathogen interactions in Mycobacterium marinum granulomas
    • Bouley, D. M., N. Ghori, K. L. Mercer, S. Falkow, and L. Ramakrishnan. 2001. Dynamic nature of host-pathogen interactions in Mycobacterium marinum granulomas. Infect. Immun. 69:7820-7831.
    • (2001) Infect. Immun. , vol.69 , pp. 7820-7831
    • Bouley, D.M.1    Ghori, N.2    Mercer, K.L.3    Falkow, S.4    Ramakrishnan, L.5
  • 4
    • 0032060482 scopus 로고    scopus 로고
    • Alkyl hydroperoxide reductase subunit C (AhpC) protects bacterial and human cells against reactive nitrogen intermediates
    • Chen, L., Q. W. Xie, and C. Nathan. 1998. Alkyl hydroperoxide reductase subunit C (AhpC) protects bacterial and human cells against reactive nitrogen intermediates. Mol. Cell 1:795-805.
    • (1998) Mol. Cell , vol.1 , pp. 795-805
    • Chen, L.1    Xie, Q.W.2    Nathan, C.3
  • 5
    • 0035815274 scopus 로고    scopus 로고
    • Structural basis of the redox switch in the OxyR transcription factor
    • Choi, H., S. Kim, P. Mukhopadhyay, S. Cho, J. Woo, G. Storz, and S. Ryu. 2001. Structural basis of the redox switch in the OxyR transcription factor. Cell 105:103-113.
    • (2001) Cell , vol.105 , pp. 103-113
    • Choi, H.1    Kim, S.2    Mukhopadhyay, P.3    Cho, S.4    Woo, J.5    Storz, G.6    Ryu, S.7
  • 6
    • 0000539718 scopus 로고
    • Effect of environmental temperatures on infection with Mycobacterium marinum (balnei) of mice and a number of poikilothermic species
    • Clark, H. F., and C. C. Shepard. 1963. Effect of environmental temperatures on infection with Mycobacterium marinum (balnei) of mice and a number of poikilothermic species. J. Bacteriol. 86:1057-1069.
    • (1963) J. Bacteriol. , vol.86 , pp. 1057-1069
    • Clark, H.F.1    Shepard, C.C.2
  • 8
    • 0028076783 scopus 로고
    • Gene expression in mycobacteria: Transcriptional fusions based on xylE and analysis of the promoter region of the response regulator mtrA from Mycobacterium tuberculosis
    • Curcic, R., S. Dhandayuthapani, and V. Deretic. 1994. Gene expression in mycobacteria: transcriptional fusions based on xylE and analysis of the promoter region of the response regulator mtrA from Mycobacterium tuberculosis. Mol. Microbiol. 13:1057-1064.
    • (1994) Mol. Microbiol. , vol.13 , pp. 1057-1064
    • Curcic, R.1    Dhandayuthapani, S.2    Deretic, V.3
  • 9
    • 0029959745 scopus 로고    scopus 로고
    • The extreme sensitivity of Mycobacterium tuberculosis to the front-line antituberculosis drug isoniazid
    • Deretic, V., E. Pagan-Ramos, Y. Zhang, S. Dhandayuthapani, and L. E. Via. 1996. The extreme sensitivity of Mycobacterium tuberculosis to the front-line antituberculosis drug isoniazid. Nat. Biotechnol. 14:1557-1561.
    • (1996) Nat. Biotechnol. , vol.14 , pp. 1557-1561
    • Deretic, V.1    Pagan-Ramos, E.2    Zhang, Y.3    Dhandayuthapani, S.4    Via, L.E.5
  • 10
    • 0028882958 scopus 로고
    • Mycobacterium tuberculosis is a natural mutant with an inactivated oxidative-stress regulatory gene: Implications for sensitivity to isoniazid
    • Deretic, V., W. Philipp, S. Dhandayuthapani, M. H. Mudd, R. Curcic, T. Garbe, B. Heym, L. E. Via, and S. T. Cole. 1995. Mycobacterium tuberculosis is a natural mutant with an inactivated oxidative-stress regulatory gene: implications for sensitivity to isoniazid. Mol. Microbiol. 17:889-900.
    • (1995) Mol. Microbiol. , vol.17 , pp. 889-900
    • Deretic, V.1    Philipp, W.2    Dhandayuthapani, S.3    Mudd, M.H.4    Curcic, R.5    Garbe, T.6    Heym, B.7    Via, L.E.8    Cole, S.T.9
  • 11
  • 12
    • 0030910666 scopus 로고    scopus 로고
    • Interactions of OxyR with the promoter region of the oxyR and ahpC genes from Mycobacterium leprae and Mycobacterium tuberculosis
    • Dhandayuthapani, S., M. Mudd, and V. Deretic. 1997. Interactions of OxyR with the promoter region of the oxyR and ahpC genes from Mycobacterium leprae and Mycobacterium tuberculosis. J. Bacteriol. 179:2401-2409.
    • (1997) J. Bacteriol. , vol.179 , pp. 2401-2409
    • Dhandayuthapani, S.1    Mudd, M.2    Deretic, V.3
  • 13
    • 0029888258 scopus 로고    scopus 로고
    • Oxidative stress response and its role in sensitivity to isoniazid in mycobacteria: Characterization and inducibility of ahpC by peroxides in Mycobacterium smegmatis and lack of expression in M. aurum and M. tuberculosis
    • Dhandayuthapani, S., Y. Zhang, M. H. Mudd, and V. Deretic. 1996. Oxidative stress response and its role in sensitivity to isoniazid in mycobacteria: characterization and inducibility of ahpC by peroxides in Mycobacterium smegmatis and lack of expression in M. aurum and M. tuberculosis. J. Bacteriol. 178:3641-3649.
    • (1996) J. Bacteriol. , vol.178 , pp. 3641-3649
    • Dhandayuthapani, S.1    Zhang, Y.2    Mudd, M.H.3    Deretic, V.4
  • 14
    • 0035380710 scopus 로고    scopus 로고
    • Entry mechanisms of mycobacteria
    • El Etr, S. H., and J. D. Cirillo. 2001. Entry mechanisms of mycobacteria. Front. Biosci. 6:D737-D747.
    • (2001) Front. Biosci. , vol.6
    • El Etr, S.H.1    Cirillo, J.D.2
  • 15
    • 0037306244 scopus 로고    scopus 로고
    • Transposon mutagenesis of Mycobacterium marinum identifies a locus linking pigmentation and intracellular survival
    • Gao, L. Y., R. Groger, J. S. Cox, S. M. Beverley, E. H. Lawson, and E. J. Brown. 2003. Transposon mutagenesis of Mycobacterium marinum identifies a locus linking pigmentation and intracellular survival. Infect. Immun. 71:922-929.
    • (2003) Infect. Immun. , vol.71 , pp. 922-929
    • Gao, L.Y.1    Groger, R.2    Cox, J.S.3    Beverley, S.M.4    Lawson, E.H.5    Brown, E.J.6
  • 16
    • 12244289618 scopus 로고    scopus 로고
    • Genome-wide analysis of synonymous single nucleotide polymorphisms in Mycobacterium tuberculosis complex organisms: Resolution of genetic relationships among closely related microbial strains
    • Gutacker, M. M., J. C. Smoot, C. A. Migliaccio, S. M. Ricklefs, S. Hua, D. V. Cousins, E. A. Graviss, E. Shashkina, B. N. Kreiswirth, and J. M. Musser. 2002. Genome-wide analysis of synonymous single nucleotide polymorphisms in Mycobacterium tuberculosis complex organisms: resolution of genetic relationships among closely related microbial strains. Genetics 162:1533-1543.
    • (2002) Genetics , vol.162 , pp. 1533-1543
    • Gutacker, M.M.1    Smoot, J.C.2    Migliaccio, C.A.3    Ricklefs, S.M.4    Hua, S.5    Cousins, D.V.6    Graviss, E.A.7    Shashkina, E.8    Kreiswirth, B.N.9    Musser, J.M.10
  • 17
    • 0014407087 scopus 로고
    • Mycobacterium tuberculosis in macrophages: Effect of certain surfactants and other membrane-active compounds
    • Hart, P. D. 1968. Mycobacterium tuberculosis in macrophages: effect of certain surfactants and other membrane-active compounds. Science 162:686-689.
    • (1968) Science , vol.162 , pp. 686-689
    • Hart, P.D.1
  • 18
    • 0030572708 scopus 로고    scopus 로고
    • Nitrosative stress: Activation of the transcription factor OxyR
    • Hausladen, A., C. T. Privalle, T. Keng, J. DeAngelo, and J. S. Stamler. 1996. Nitrosative stress: activation of the transcription factor OxyR. Cell 86:719-729.
    • (1996) Cell , vol.86 , pp. 719-729
    • Hausladen, A.1    Privalle, C.T.2    Keng, T.3    Deangelo, J.4    Stamler, J.S.5
  • 20
    • 0029907767 scopus 로고    scopus 로고
    • Lack of expression of the global regulator OxyR in Haemophilia influenzae has a profound effect on growth phenotype
    • Maciver, I., and E. J. Hansen. 1996. Lack of expression of the global regulator OxyR in Haemophilia influenzae has a profound effect on growth phenotype. Infect. Immun. 64:4618-4629.
    • (1996) Infect. Immun. , vol.64 , pp. 4618-4629
    • Maciver, I.1    Hansen, E.J.2
  • 21
    • 0034529994 scopus 로고    scopus 로고
    • Latent Mycobacterium tuberculosis-persistence, patience, and winning by waiting
    • Manabe, Y. C., and W. R. Bishai. 2000. Latent Mycobacterium tuberculosis-persistence, patience, and winning by waiting. Nat. Med. 6:1327-1329.
    • (2000) Nat. Med. , vol.6 , pp. 1327-1329
    • Manabe, Y.C.1    Bishai, W.R.2
  • 22
    • 0036772990 scopus 로고    scopus 로고
    • Oxidative stress response genes in Mycobacterium tuberculosis: Role of ahpC in resistance to peroxynitrite and stage-specific survival in macrophages
    • Master, S. S., B. Springer, P. Sander, E. C. Boettger, V. Deretic, and G. S. Timmins. 2002. Oxidative stress response genes in Mycobacterium tuberculosis: role of ahpC in resistance to peroxynitrite and stage-specific survival in macrophages. Microbiology 148:3139-3144.
    • (2002) Microbiology , vol.148 , pp. 3139-3144
    • Master, S.S.1    Springer, B.2    Sander, P.3    Boettger, E.C.4    Deretic, V.5    Timmins, G.S.6
  • 23
    • 2942538880 scopus 로고    scopus 로고
    • Role of KatG catalase-peroxidase in mycobacterial pathogenesis: Countering the phagocyte oxidative burst
    • Ng, V. H., J. S. Cox, A. O. Sousa, J. D. MacMicking, and J. D. McKinney. 2004. Role of KatG catalase-peroxidase in mycobacterial pathogenesis: countering the phagocyte oxidative burst. Mol. Microbiol. 52:1291-1302.
    • (2004) Mol. Microbiol. , vol.52 , pp. 1291-1302
    • Ng, V.H.1    Cox, J.S.2    Sousa, A.O.3    MacMicking, J.D.4    McKinney, J.D.5
  • 24
    • 0031660550 scopus 로고    scopus 로고
    • Oxidative stress response and characterization of the oxyR-ahpC and furA-katG loci in Mycobacterium marinum
    • Pagan-Ramos, E., J. Song, M. McFalone, M. H. Mudd, and V. Deretic. 1998. Oxidative stress response and characterization of the oxyR-ahpC and furA-katG loci in Mycobacterium marinum. J. Bacteriol. 180:4856-4864.
    • (1998) J. Bacteriol. , vol.180 , pp. 4856-4864
    • Pagan-Ramos, E.1    Song, J.2    McFalone, M.3    Mudd, M.H.4    Deretic, V.5
  • 25
    • 0034717008 scopus 로고    scopus 로고
    • Granuloma-specific expression of Mycobacterium virulence proteins from the glycine-rich PE-PGRS family
    • Ramakrishnan, L., N. A. Federspiel, and S. Falkow. 2000. Granuloma-specific expression of Mycobacterium virulence proteins from the glycine-rich PE-PGRS family. Science 288:1436-1439.
    • (2000) Science , vol.288 , pp. 1436-1439
    • Ramakrishnan, L.1    Federspiel, N.A.2    Falkow, S.3
  • 26
    • 0031018261 scopus 로고    scopus 로고
    • Mycobacterium marinum causes both long-term subclinical infection and acute disease in the leopard frog (Rana pipiens)
    • Ramakrishnan, L., R. H. Valdivia, J. H. McKerrow, and S. Falkow. 1997. Mycobacterium marinum causes both long-term subclinical infection and acute disease in the leopard frog (Rana pipiens). Infect. Immun. 65:767-773.
    • (1997) Infect. Immun. , vol.65 , pp. 767-773
    • Ramakrishnan, L.1    Valdivia, R.H.2    McKerrow, J.H.3    Falkow, S.4
  • 30
    • 0021963581 scopus 로고
    • Evidence for the generation of active oxygen by isoniazid treatment of extracts of Mycobacterium tuberculosis H37Ra
    • Shoeb, H. A., B. U. Bowman, Jr., A. C. Ottolenghi, and A. J. Merola. 1985. Evidence for the generation of active oxygen by isoniazid treatment of extracts of Mycobacterium tuberculosis H37Ra. Antimicrob. Agents Chemother. 27:404-407.
    • (1985) Antimicrob. Agents Chemother. , vol.27 , pp. 404-407
    • Shoeb, H.A.1    Bowman Jr., B.U.2    Ottolenghi, A.C.3    Merola, A.J.4
  • 31
    • 0034826633 scopus 로고    scopus 로고
    • Silencing of oxidative stress response in Mycobacterium tuberculosis: Expression patterns of ahpC in virulent and avirulent strains and effect of ahpC inactivation
    • Springer, B., S. Master, P. Sander, T. Zahrt, M. McFalone, J. Song, K. G. Papavinasasundaram, M. J. Colston, E. Boettger, and V. Deretic. 2001. Silencing of oxidative stress response in Mycobacterium tuberculosis: expression patterns of ahpC in virulent and avirulent strains and effect of ahpC inactivation. Infect. Immun. 69:5967-5973.
    • (2001) Infect. Immun. , vol.69 , pp. 5967-5973
    • Springer, B.1    Master, S.2    Sander, P.3    Zahrt, T.4    McFalone, M.5    Song, J.6    Papavinasasundaram, K.G.7    Colston, M.J.8    Boettger, E.9    Deretic, V.10
  • 33
    • 0025214474 scopus 로고
    • Transcriptional regulator of oxidative stress-inducible genes: Direct activation by oxidation
    • Storz, G., L. A. Tartaglia, and B. N. Ames. 1990. Transcriptional regulator of oxidative stress-inducible genes: direct activation by oxidation. Science 248:189-194.
    • (1990) Science , vol.248 , pp. 189-194
    • Storz, G.1    Tartaglia, L.A.2    Ames, B.N.3
  • 34
    • 0034133604 scopus 로고    scopus 로고
    • Transformation and transposition of the genome of Mycobacterium marinum
    • Talaat, A. M., and M. Trucksis. 2000. Transformation and transposition of the genome of Mycobacterium marinum. Am. J. Vet. Res. 61:125-128.
    • (2000) Am. J. Vet. Res. , vol.61 , pp. 125-128
    • Talaat, A.M.1    Trucksis, M.2
  • 35
    • 0031814102 scopus 로고    scopus 로고
    • The Salmonella typhimurium AhpC polypeptide is not essential for virulence in BALB/c mice but is recognized as an antigen during infection
    • Taylor, P. D., C. J. Inchley, and M. P. Gallagher. 1998. The Salmonella typhimurium AhpC polypeptide is not essential for virulence in BALB/c mice but is recognized as an antigen during infection. Infect. Immun. 66:3208-3217.
    • (1998) Infect. Immun. , vol.66 , pp. 3208-3217
    • Taylor, P.D.1    Inchley, C.J.2    Gallagher, M.P.3
  • 36
    • 3342880792 scopus 로고    scopus 로고
    • Nitric oxide generated from isoniazid activation by KatG: Source of nitric oxide and activity against Mycobacterium tuberculosis
    • Timmins, G. S., S. Master, F. Rusnak, and V. Deretic. 2004. Nitric oxide generated from isoniazid activation by KatG: source of nitric oxide and activity against Mycobacterium tuberculosis. Antimicrob. Agents Chemother. 48:3006-3009.
    • (2004) Antimicrob. Agents Chemother. , vol.48 , pp. 3006-3009
    • Timmins, G.S.1    Master, S.2    Rusnak, F.3    Deretic, V.4
  • 37
    • 3843139374 scopus 로고    scopus 로고
    • Requirements for nitric oxide generation from isoniazid activation in vitro and inhibition of mycobacterial respiration in vivo
    • Timmins, G. S., S. Master, F. Rusnak, and V. Deretic. 2004. Requirements for nitric oxide generation from isoniazid activation in vitro and inhibition of mycobacterial respiration in vivo. J. Bacteriol. 186:5427-5431.
    • (2004) J. Bacteriol. , vol.186 , pp. 5427-5431
    • Timmins, G.S.1    Master, S.2    Rusnak, F.3    Deretic, V.4
  • 38
    • 0031943169 scopus 로고    scopus 로고
    • Differentiation of Mycobacterium ulcerans, M. marinum, and M. haemophilum: Mapping of their relationships to M. tuberculosis by fatty acid profile analysis, DNA-DNA hybridization, and 16S rRNA gene sequence analysis
    • Tonjum, T., D. B. Welty, E. Jantzen, and P. L. Small. 1998. Differentiation of Mycobacterium ulcerans, M. marinum, and M. haemophilum: mapping of their relationships to M. tuberculosis by fatty acid profile analysis, DNA-DNA hybridization, and 16S rRNA gene sequence analysis. J. Clin. Microbiol. 36:918-925.
    • (1998) J. Clin. Microbiol. , vol.36 , pp. 918-925
    • Tonjum, T.1    Welty, D.B.2    Jantzen, E.3    Small, P.L.4
  • 40
    • 0020469062 scopus 로고
    • Disk diffusion testing with polymyxin and amikacin for differentiation of Mycobacterium fortuilum and Mycobacterium chelonei
    • Wallace, R. J., Jr., J. M. Swenson, V. A. Silcox, and R. C. Good. 1982. Disk diffusion testing with polymyxin and amikacin for differentiation of Mycobacterium fortuilum and Mycobacterium chelonei. J. Clin. Microbiol. 16:1003-1006.
    • (1982) J. Clin. Microbiol. , vol.16 , pp. 1003-1006
    • Wallace Jr., R.J.1    Swenson, J.M.2    Silcox, V.A.3    Good, R.C.4
  • 41
    • 0035979346 scopus 로고    scopus 로고
    • Evidence for isoniazid-dependent free radical generation catalyzed by Mycobacterium tuberculosis KatG and the isoniazid-resistant mutant KatG(S315T)
    • Wengenack, N. L., and F. Rusnak. 2001. Evidence for isoniazid-dependent free radical generation catalyzed by Mycobacterium tuberculosis KatG and the isoniazid-resistant mutant KatG(S315T). Biochemistry 40:8990-8996.
    • (2001) Biochemistry , vol.40 , pp. 8990-8996
    • Wengenack, N.L.1    Rusnak, F.2
  • 42
    • 0034130852 scopus 로고    scopus 로고
    • An essential two-component signal transduction system in Mycobacterium tuberculosis
    • Zahrt, T. C., and V. Deretic. 2000. An essential two-component signal transduction system in Mycobacterium tuberculosis. J. Bacteriol. 182:3832-3838.
    • (2000) J. Bacteriol. , vol.182 , pp. 3832-3838
    • Zahrt, T.C.1    Deretic, V.2
  • 43
    • 0035100597 scopus 로고    scopus 로고
    • Mycobacterial FurA is a negative regulator of catalase-peroxidase gene katG
    • Zahrt, T. C., J. Song, J. Siple, and V. Deretic. 2001. Mycobacterial FurA is a negative regulator of catalase-peroxidase gene katG. Mol. Microbiol. 39:1174-1185.
    • (2001) Mol. Microbiol. , vol.39 , pp. 1174-1185
    • Zahrt, T.C.1    Song, J.2    Siple, J.3    Deretic, V.4
  • 44
    • 0029830769 scopus 로고    scopus 로고
    • Molecular basis for the exquisite sensitivity of Mycobacterium tuberculosis to isoniazid
    • Zhang, Y., S. Dhandayuthapani, and V. Deretic. 1996. Molecular basis for the exquisite sensitivity of Mycobacterium tuberculosis to isoniazid. Proc. Natl. Acad. Sci. USA 93:13212-13216.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 13212-13216
    • Zhang, Y.1    Dhandayuthapani, S.2    Deretic, V.3


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